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Enhancer malfunction in cancer
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scholarly article
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PubMed
review article
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Europe PubMed Central
title
Enhancer malfunction in cancer
(English)
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stated in
PubMed
author
Ali Shilatifard
series ordinal
3
0 references
author name string
Hans-Martin Herz
series ordinal
1
1 reference
stated in
Crossref
Deqing Hu
series ordinal
2
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stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
20 March 2014
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stated in
PubMed
published in
Molecular Cell
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stated in
PubMed
volume
53
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stated in
PubMed
page(s)
859-66
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stated in
PubMed
issue
6
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PubMed
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The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers
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DNA methylation of distal regulatory sites characterizes dysregulation of cancer genes
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Cohesin at active genes: a unifying theme for cohesin and gene expression from model organisms to humans
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The Drosophila ortholog of MLL3 and MLL4, trithorax related, functions as a negative regulator of tissue growth
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Enhancer-associated H3K4 monomethylation by Trithorax-related, the Drosophila homolog of mammalian Mll3/Mll4
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dSet1 is the main H3K4 di- and tri-methyltransferase throughout Drosophila development
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Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity
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Drosophila Set1 is the major histone H3 lysine 4 trimethyltransferase with role in transcription.
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The role of chromatin accessibility in directing the widespread, overlapping patterns of Drosophila transcription factor binding
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28 September 2017
A cis-regulatory map of the Drosophila genome.
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Enhancer function: new insights into the regulation of tissue-specific gene expression
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Transcriptional enhancers in animal development and evolution
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28 September 2017
Genomics of long-range regulatory elements
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The H3K27me3 demethylase dUTX is a suppressor of Notch- and Rb-dependent tumors in Drosophila
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28 September 2017
Functional enhancers at the gene-poor 8q24 cancer-linked locus.
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A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4
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Histone replacement marks the boundaries of cis-regulatory domains
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Drosophila GAGA factor directs histone H3.3 replacement that prevents the heterochromatin spreading
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28 September 2017
Hotspots of transcription factor colocalization in the genome of Drosophila melanogaster
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Effects of sister chromatid cohesion proteins on cut gene expression during wing development in Drosophila
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Drosophila nipped-B protein supports sister chromatid cohesion and opposes the stromalin/Scc3 cohesion factor to facilitate long-range activation of the cut gene
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Distant liaisons: long-range enhancer-promoter interactions in Drosophila.
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28 September 2017
Nipped-B, a Drosophila homologue of chromosomal adherins, participates in activation by remote enhancers in the cut and Ultrabithorax genes.
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Sequences controlling in vitro transcription of SV40 promoters
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Transcriptional ‘enhancers’ from SV40 and polyoma virus show a cell type preference
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28 September 2017
Expression of a β-globin gene is enhanced by remote SV40 DNA sequences
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28 September 2017
The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants
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Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits
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31 May 2018
Enhancer dysfunction: how the main regulators of gene expression contribute to cancer
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31 May 2018
HOT regions function as patterned developmental enhancers and have a distinct cis-regulatory signature
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A transcription enhancer in the Herpesvirus saimiri genome
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DNA methylation of transcriptional enhancers and cancer predisposition.
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28 November 2018
Mice lacking a Myc enhancer that includes human SNP rs6983267 are resistant to intestinal tumors.
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28 November 2018
Molecular regulation of histone H3 trimethylation by COMPASS and the regulation of gene expression
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Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes
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Identification of a hot spot for microdeletions in patients with X- linked deafness type 3 (DFN3) 900 kb proximal to the DFN3 gene POU3F4
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Identifiers
DOI
10.1016/J.MOLCEL.2014.02.033
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
475981
OpenCitations bibliographic resource ID
475981
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
475981
PMCID
4049186
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
475981
PubMed ID
24656127
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
475981
ResearchGate publication ID
261032564
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