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Recent progress in structure-based anti-influenza drug design
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Europe PubMed Central
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3459301
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22704956%20AND%20SRC:MED&resulttype=core&format=json
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5 February 2020
title
Recent progress in structure-based anti-influenza drug design
(English)
2 references
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PubMed
stated in
Europe PubMed Central
PMC publication ID
3459301
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22704956%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
author
Huan-Xiang Zhou
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3
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Europe PubMed Central
PMC publication ID
3459301
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22704956%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
author name string
Juan Du
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1
2 references
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Crossref
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Europe PubMed Central
PMC publication ID
3459301
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22704956%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
Timothy A Cross
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2
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Europe PubMed Central
PMC publication ID
3459301
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22704956%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
language of work or name
English
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publication date
13 June 2012
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Europe PubMed Central
PMC publication ID
3459301
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retrieved
5 February 2020
published in
Drug Discovery Today
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
3459301
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22704956%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
volume
17
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
3459301
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22704956%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
issue
19-20
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
3459301
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22704956%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
page(s)
1111-1120
1 reference
stated in
Europe PubMed Central
PMC publication ID
3459301
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22704956%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
cites work
M2 protein from influenza A: from multiple structures to biophysical and functional insights
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Antibody recognition of a highly conserved influenza virus epitope
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Structure and mechanism of the M2 proton channel of influenza A virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Insight into the Mechanism of the Influenza A Proton Channel from a Structure in a Lipid Bilayer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Structures of Receptor Complexes of a North American H7N2 Influenza Hemagglutinin with a Loop Deletion in the Receptor Binding Site
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Nucleoside Monophosphate Complex Structures of the Endonuclease Domain from the Influenza Virus Polymerase PA Subunit Reveal the Substrate Binding Site inside the Catalytic Center
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
The structure of a biologically active influenza virus ribonucleoprotein complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Structural insight into the essential PB1–PB2 subunit contact of the influenza virus RNA polymerase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Structural Basis of the Influenza A Virus RNA Polymerase PB2 RNA-binding Domain Containing the Pathogenicity-determinant Lysine 627 Residue
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Structural basis for dsRNA recognition by NS1 protein of influenza A virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Structural basis for suppression of a host antiviral response by influenza A virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
The structural basis for an essential subunit interaction in influenza virus RNA polymerase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Crystal structure of the polymerase PA(C)-PB1(N) complex from an avian influenza H5N1 virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Structure of the influenza virus A H5N1 nucleoprotein: implications for RNA binding, oligomerization, and vaccine design
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Viral membrane fusion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
The structural basis for cap binding by influenza virus polymerase subunit PB2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Structural basis for the function and inhibition of an influenza virus proton channel
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Backbone Structure of the Amantadine-Blocked Trans-Membrane Domain M2 Proton Channel from Influenza A Virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
The mechanism by which influenza A virus nucleoprotein forms oligomers and binds RNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
The structure and receptor binding properties of the 1918 influenza hemagglutinin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Crystal structure of the M1 protein-binding domain of the influenza A virus nuclear export protein (NEP/NS2)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
X-ray structures of H5 avian and H9 swine influenza virus hemagglutinins bound to avian and human receptor analogs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Combined results from solution studies on intact influenza virus M1 protein and from a new crystal form of its N-terminal domain show that M1 is an elongated monomer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Structure of a bifunctional membrane-RNA binding protein, influenza virus matrix protein M1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
A sialic acid-derived phosphonate analog inhibits different strains of influenza virus neuraminidase with different efficiencies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Nuclear traffic of influenza virus proteins and ribonucleoprotein complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
A novel influenza A virus mitochondrial protein that induces cell death.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Inhibition of influenza virus replication in tissue culture by 2-deoxy-2,3-dehydro-N-trifluoroacetylneuraminic acid (FANA): mechanism of action
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
The gate of the influenza virus M2 proton channel is formed by a single tryptophan residue
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
The multifunctional NS1 protein of influenza A viruses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
The war against influenza: discovery and development of sialidase inhibitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Large-scale sequencing of human influenza reveals the dynamic nature of viral genome evolution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Chemical rescue of histidine selectivity filter mutants of the M2 ion channel of influenza A virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Structure-based drug design of a new chemical class of small molecules active against influenza A nucleoprotein in vitro and in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Anti-influenza activity of marchantins, macrocyclic bisbibenzyls contained in liverworts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
21 March 2017
Rational design of potent sialidase-based inhibitors of influenza virus replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
7 April 2017
Structure and receptor specificity of the hemagglutinin from an H5N1 influenza virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
7 April 2017
E339...R416 salt bridge of nucleoprotein as a feasible target for influenza virus inhibitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Exploring organosilane amines as potent inhibitors and structural probes of influenza a virus M2 proton channel
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Mechanism of 150-cavity formation in influenza neuraminidase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Exploring the size limit of templates for inhibitors of the M2 ion channel of influenza A virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Influenza virus assembly and budding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Discovery of highly potent agents against influenza A virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
High-throughput identification of compounds targeting influenza RNA-dependent RNA polymerase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Structure-based design of NS2 mutants for attenuated influenza A virus vaccines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Identification of influenza A nucleoprotein as an antiviral target
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Discovery of novel 1-phenyl-cycloalkane carbamides as potent and selective influenza fusion inhibitors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Functional analysis of the influenza virus H5N1 nucleoprotein tail loop reveals amino acids that are crucial for oligomerization and ribonucleoprotein activities
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Analogs of zanamivir with modified C4-substituents as the inhibitors against the group-1 neuraminidases of influenza viruses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Potential drug-like inhibitors of Group 1 influenza neuraminidase identified through computer-aided drug design
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Identification of hits as matrix-2 protein inhibitors through the focused screening of a small primary amine library
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Structures of influenza A proteins and insights into antiviral drug targets.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Combinatorial design of avian influenza neuraminidase inhibitors containing pyrrolidine core with a reduced susceptibility to viral drug resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Design and pharmacological characterization of inhibitors of amantadine-resistant mutants of the M2 ion channel of influenza A virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Large-scale sequence analysis of M gene of influenza A viruses from different species: mechanisms for emergence and spread of amantadine resistance.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Discovery of spiro-piperidine inhibitors and their modulation of the dynamics of the M2 proton channel from influenza A virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Design of oseltamivir analogs inhibiting neuraminidase of avian influenza virus H5N1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Emerging antiviral targets for influenza A virus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
A novel small-molecule inhibitor of the avian influenza H5N1 virus determined through computational screening against the neuraminidase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Oseltamivir-resistant influenza virus A (H1N1), Europe, 2007-08 season
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
On the structure-based design of novel inhibitors of H5N1 influenza A virus neuraminidase (NA).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Novel influenza virus NS1 antagonists block replication and restore innate immune function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Design of multi-binding-site inhibitors, ligand efficiency, and consensus screening of avian influenza H5N1 wild-type neuraminidase and of the oseltamivir-resistant H274Y variant
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
The influenza virus M2 protein cytoplasmic tail interacts with the M1 protein and influences virus assembly at the site of virus budding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Ensemble-based virtual screening reveals potential novel antiviral compounds for avian influenza neuraminidase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
A secondary gate as a mechanism for inhibition of the M2 proton channel by amantadine.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Surveillance of resistance to adamantanes among influenza A(H3N2) and A(H1N1) viruses isolated worldwide
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Calculation of protein-ligand binding affinities.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Histidines, heart of the hydrogen ion channel from influenza A virus: toward an understanding of conductance and proton selectivity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
The CPSF30 binding site on the NS1A protein of influenza A virus is a potential antiviral target.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
High levels of adamantane resistance among influenza A (H3N2) viruses and interim guidelines for use of antiviral agents--United States, 2005-06 influenza season.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Susceptibilities of antiviral-resistant influenza viruses to novel neuraminidase inhibitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Neuraminidase inhibitor-resistant influenza viruses may differ substantially in fitness and transmissibility
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Restriction of viral replication by mutation of the influenza virus matrix protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
The influenza virus nucleoprotein: a multifunctional RNA-binding protein pivotal to virus replication.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
In vitro characterization of A-315675, a highly potent inhibitor of A and B strain influenza virus neuraminidases and influenza virus replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Selection of influenza virus mutants in experimentally infected volunteers treated with oseltamivir
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Influenza virus matrix protein is the major driving force in virus budding.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
BCX-1812 (RWJ-270201): discovery of a novel, highly potent, orally active, and selective influenza neuraminidase inhibitor through structure-based drug design
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Resistance of influenza viruses to neuraminidase inhibitors--a review.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Global epidemiology of influenza: past and present.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Influenza A and B viruses expressing altered NS1 proteins: A vaccine approach
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Inhibition of influenza virus hemagglutinin-mediated membrane fusion by a compound related to podocarpic acid
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Growth impairment resulting from expression of influenza virus M2 protein in Saccharomyces cerevisiae: identification of a novel inhibitor of influenza virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Variation of influenza A, B, and C viruses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
The molecular biology of influenza virus pathogenicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Comparison of complete amino acid sequences and receptor-binding properties among 13 serotypes of hemagglutinins of influenza A viruses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 September 2017
Molecular dynamics simulation directed rational design of inhibitors targeting drug-resistant mutants of influenza A virus M2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
31 May 2018
Exploring the Requirements for the Hydrophobic Scaffold and Polar Amine in inhibitors of M2 from Influenza A Virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
31 May 2018
Proposed lead molecules against Hemagglutinin of avian influenza virus (H5N1).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
31 May 2018
Peptide-mediated interference with influenza A virus polymerase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
31 May 2018
Inhibition of the fusion-inducing conformational change of influenza hemagglutinin by benzoquinones and hydroquinones
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
31 May 2018
Nuclear transport of influenza virus ribonucleoproteins: the viral matrix protein (M1) promotes export and inhibits import
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
31 May 2018
Are the 5' ends of influenza viral mRNAs synthesized in vivo donated by host mRNAs?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
31 May 2018
Three new powerful oseltamivir derivatives for inhibiting the neuraminidase of influenza virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 November 2018
Computational design of novel, high-affinity neuraminidase inhibitors for H5N1 avian influenza virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 November 2018
Rational design of Tamiflu derivatives targeting at the open conformation of neuraminidase subtype 1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 November 2018
Update: drug susceptibility of swine-origin influenza A (H1N1) viruses, April 2009.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 November 2018
Remarkable loop flexibility in avian influenza N1 and its implications for antiviral drug design.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 November 2018
Adamantane resistance among influenza A viruses isolated early during the 2005-2006 influenza season in the United States
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 November 2018
Highly potent and long-acting trimeric and tetrameric inhibitors of influenza virus neuraminidase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 November 2018
An approach to the identification of potent inhibitors of influenza virus fusion using parallel synthesis methodology
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459301
retrieved
28 November 2018
Identifiers
DOI
10.1016/J.DRUDIS.2012.06.002
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3831435
stated in
Europe PubMed Central
PMC publication ID
3459301
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22704956%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
Fatcat ID
release_zxi3lct6kvf2vipt6dwl6jispm
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/zxi3lct6kvf2vipt6dwl6jispm
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
OpenCitations bibliographic resource ID
3831435
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3831435
PMC publication ID
3459301
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3831435
stated in
Europe PubMed Central
PMC publication ID
3459301
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22704956%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
PubMed publication ID
22704956
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3831435
stated in
Europe PubMed Central
PMC publication ID
3459301
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22704956%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
ResearchGate publication ID
227168813
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