(Q30356303)

20 June 2017

The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design. (English)

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20 June 2017

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8

Steven J Gamblin

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20 June 2017

9

John J Skehel

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20 June 2017

Rupert J Russell

1

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20 June 2017

Lesley F Haire

2

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20 June 2017

David J Stevens

3

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20 June 2017

Patrick J Collins

4

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20 June 2017

Yi Pu Lin

5

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20 June 2017

G Michael Blackburn

6

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20 June 2017

Alan J Hay

7

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20 June 2017

language of work or name

English

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publication date

16 August 2006

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20 June 2017

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20 June 2017

443

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20 June 2017

45-49

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20 June 2017

7107

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Characterization of the surface proteins of influenza A (H5N1) viruses isolated from humans in 1997-1998.

20 June 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Evolution of H5N1 avian influenza viruses in Asia

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Rational design of potent sialidase-based inhibitors of influenza virus replication

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Structure of the influenza virus glycoprotein antigen neuraminidase at 2.9 A resolution

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Three-dimensional structure of neuraminidase of subtype N9 from an avian influenza virus.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

The 2.2 A resolution crystal structure of influenza B neuraminidase and its complex with sialic acid

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Selection of influenza virus mutants in experimentally infected volunteers treated with oseltamivir

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Influenza virus carrying neuraminidase with reduced sensitivity to oseltamivir carboxylate has altered properties in vitro and is compromised for infectivity and replicative ability in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Oseltamivir (Tamiflu) and its potential for use in the event of an influenza pandemic.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Pyrrolidinobenzoic acid inhibitors of influenza virus neuraminidase: modifications of essential pyrrolidinone ring substituents.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

H5N1 outbreaks and enzootic influenza

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Structure of the catalytic and antigenic sites in influenza virus neuraminidase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Three-dimensional structure of influenza A N9 neuraminidase and its complex with the inhibitor 2-deoxy 2,3-dehydro-N-acetyl neuraminic acid

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Influenza B virus neuraminidase can synthesize its own inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Inhibition of neuraminidase activity by derivatives of 2-deoxy-2,3-dehydro-N-acetylneuraminic acid

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

BCX-1812 (RWJ-270201): discovery of a novel, highly potent, orally active, and selective influenza neuraminidase inhibitor through structure-based drug design

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Susceptibilities of antiviral-resistant influenza viruses to novel neuraminidase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Mechanism by which mutations at his274 alter sensitivity of influenza a virus n1 neuraminidase to oseltamivir carboxylate and zanamivir

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Neuraminidase inhibitor-resistant influenza viruses may differ substantially in fitness and transmissibility

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Avian flu: isolation of drug-resistant H5N1 virus.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Resistant influenza A viruses in children treated with oseltamivir: descriptive study

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Oseltamivir resistance during treatment of influenza A (H5N1) infection

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Transmission of equine influenza virus to dogs

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

X-ray structures of H5 avian and H9 swine influenza virus hemagglutinins bound to avian and human receptor analogs

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

The CCP4 suite: programs for protein crystallography

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05114

7 January 2021

Identifiers

DOI

10.1038/NATURE05114

1 reference

Dimensions Publication ID

20 June 2017

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1 reference