(Q26863735)

English

IRAK signalling in cancer

scientific article

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scholarly article

1 reference

1 reference

8 February 2021

IRAK signalling in cancer (English)

1 reference

interleukin-1 receptor-associated kinases

1 reference

20 November 2019

signal transduction

1 reference

26 August 2020

1 reference

8 February 2021

author name string

G W Rhyasen

1

1 reference

D T Starczynowski

2

1 reference

language of work or name

1 reference

publication date

20 January 2015

6 references

3 April 2019

28 September 2019

20 November 2019

26 August 2020

8 February 2021

British Journal of Cancer

6 references

3 April 2019

28 September 2019

20 November 2019

26 August 2020

8 February 2021

112

1 reference

2

1 reference

232-7

1 reference

copyright license

Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported

5 references

Europe PubMed Central

3 April 2019

Europe PubMed Central

28 September 2019

Europe PubMed Central

20 November 2019

Europe PubMed Central

26 August 2020

Europe PubMed Central

8 February 2021

copyright status

0 references

on focus list of Wikimedia project

0 references

Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation

1 reference

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Functional analysis of human hematopoietic stem cell gene expression using zebrafish

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21 March 2017

Tumor cells deactivate human monocytes by up-regulating IL-1 receptor associated kinase-M expression via CD44 and TLR4

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21 March 2017

IRAK-M is a negative regulator of Toll-like receptor signaling

1 reference

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21 March 2017

Overexpression of an enzymically inactive interleukin-1-receptor-associated kinase activates nuclear factor-kappaB

1 reference

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21 March 2017

Discovery of Potent and Selective Covalent Inhibitors of JNK

1 reference

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21 March 2017

Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling

1 reference

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21 March 2017

IRAK-4 inhibitors. Part II: a structure-based assessment of imidazo[1,2-a]pyridine binding

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21 March 2017

Crystal structures of IRAK-4 kinase in complex with inhibitors: a serine/threonine kinase with tyrosine as a gatekeeper

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21 March 2017

MYD88 L265P somatic mutation in Waldenström's macroglobulinemia.

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21 March 2017

Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

1 reference

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21 March 2017

Augmentation of therapeutic responses in melanoma by inhibition of IRAK-1,-4

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21 March 2017

Oncogenically active MYD88 mutations in human lymphoma

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21 March 2017

Overexpression of an enzymically inactive interleukin-1-receptor-associated kinase activates nuclear factor-κB

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22 April 2017

Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression

1 reference

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7 April 2017

Ibrutinib and indolent B-cell lymphomas.

1 reference

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28 September 2017

Two phases of inflammatory mediator production defined by the study of IRAK2 and IRAK1 knock-in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4453441

28 September 2017

Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome

1 reference

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28 September 2017

Toll-like receptor alterations in myelodysplastic syndrome

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28 September 2017

Overexpression of IL-1 receptor accessory protein in stem and progenitor cells and outcome correlation in AML and MDS.

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28 September 2017

Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation

1 reference

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28 September 2017

Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype

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28 September 2017

Infectious agents and lymphoma development: molecular and clinical aspects

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28 September 2017

Differential regulation of interleukin-1 receptor associated kinase 1 (IRAK1) splice variants

1 reference

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28 September 2017

Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4.

1 reference

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28 September 2017

Cutting edge: expression of IL-1 receptor-associated kinase-4 (IRAK-4) proteins with mutations identified in a patient with recurrent bacterial infections alters normal IRAK-4 interaction with components of the IL-1 receptor complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4453441

28 September 2017

IRAK1 serves as a novel regulator essential for lipopolysaccharide-induced interleukin-10 gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4453441

28 September 2017

IRAK4 kinase activity is redundant for interleukin-1 (IL-1) receptor-associated kinase phosphorylation and IL-1 responsiveness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4453441

28 September 2017

Sequential autophosphorylation steps in the interleukin-1 receptor-associated kinase-1 regulate its availability as an adapter in interleukin-1 signaling

1 reference

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28 September 2017

IL-18 regulates IL-1beta-dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1.

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28 September 2017

A mutation in MYD88 (L265P) supports the survival of lymphoplasmacytic cells by activation of Bruton tyrosine kinase in Waldenström macroglobulinemia.

1 reference

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31 May 2018

Loss of the innate immunity negative regulator IRAK-M leads to enhanced host immune defense against tumor growth

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31 May 2018

Selective killing of candidate AML stem cells by antibody targeting of IL1RAP.

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https://api.crossref.org/works/10.1038%2FBJC.2014.513

21 January 2018

IRAK-4 inhibitors. Part III: a series of imidazo[1,2-a]pyridines.

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2014.513

21 January 2018

IRAK-4 inhibitors. Part 1: a series of amides

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2014.513

21 January 2018

The role of IL-1β in the early tumor cell-induced angiogenic response.

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2014.513

21 January 2018

Interleukin receptor-associated kinase (IRAK-4) deficiency associated with bacterial infections and failure to sustain antibody responses

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2014.513

21 January 2018

Ginsenoside Rb1 and its metabolite compound K inhibit IRAK-1 activation--the key step of inflammation.

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2014.513

21 January 2018

Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2.

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2014.513

21 January 2018

IRAK-4 kinase activity-dependent and -independent regulation of lipopolysaccharide-inducible genes

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2014.513

21 January 2018

The interleukin-1 receptor-associated kinase is degraded by proteasomes following its phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25290089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Understanding kinase selectivity through energetic analysis of binding site waters

1 reference

https://pubmed.ncbi.nlm.nih.gov/25290089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/BJC.2014.513

1 reference

Consolidated OpenCitations Corpus – April 2017

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0 references

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

0 references

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