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A holistic approach to targeting disease with polymeric nanoparticles
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scholarly article
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PubMed
review article
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Europe PubMed Central
title
A holistic approach to targeting disease with polymeric nanoparticles
(English)
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PubMed
main subject
nanoparticle
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author name string
Christopher J. Cheng
series ordinal
1
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Crossref
Gregory T. Tietjen
series ordinal
2
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Crossref
Jennifer K. Saucier-Sawyer
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3
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W. Mark Saltzman
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4
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language of work or name
English
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publication date
April 2015
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PubMed
published in
Nature Reviews Drug Discovery
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PubMed
volume
14
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PubMed
issue
4
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PubMed
page(s)
239-47
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PubMed
cites work
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28 September 2017
Nanoparticle-delivered suicide gene therapy effectively reduces ovarian tumor burden in mice
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28 September 2017
Gold, poly(beta-amino ester) nanoparticles for small interfering RNA delivery
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28 September 2017
Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA
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28 September 2017
Convection-enhanced delivery of nanocarriers for the treatment of brain tumors
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 September 2017
Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 September 2017
Drug delivery: Stealth particles give mucus the slip
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 September 2017
Controlled surface modification with poly(ethylene)glycol enhances diffusion of PLGA nanoparticles in human cervical mucus
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 September 2017
Sustained intraspinal delivery of neurotrophic factor encapsulated in biodegradable nanoparticles following contusive spinal cord injury
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 September 2017
Biofunctional polymer nanoparticles for intra-articular targeting and retention in cartilage
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 September 2017
VivaGel (SPL7013 Gel): a candidate dendrimer--microbicide for the prevention of HIV and HSV infection
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 September 2017
New methods for direct delivery of chemotherapy for treating brain tumors.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 September 2017
Dilation and degradation of the brain extracellular matrix enhances penetration of infused polymer nanoparticles.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 September 2017
Multicenter phase II trial of Genexol-PM, a Cremophor-free, polymeric micelle formulation of paclitaxel, in patients with metastatic breast cancer.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 September 2017
Rapid transport of large polymeric nanoparticles in fresh undiluted human mucus
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 September 2017
RNAi therapeutics: a potential new class of pharmaceutical drugs
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 September 2017
Exploiting the enhanced permeability and retention effect for tumor targeting
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 September 2017
Enhancement of topical delivery from biodegradable nanoparticles.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 September 2017
Nanoscale technology of mucoadhesive interactions.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 September 2017
An overview of the pathogenesis of cystic fibrosis lung disease
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28 September 2017
Pharmacokinetics of the carmustine implant
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 September 2017
Biodegradable polymeric nanoparticles as drug delivery devices
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 September 2017
Lymph node localisation of biodegradable nanospheres surface modified with poloxamer and poloxamine block co-polymers
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 September 2017
Pharmacokinetic properties of several novel oligonucleotide analogs in mice
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 September 2017
Preclinical development and ocular biodistribution of gemini-DNA nanoparticles after intravitreal and topical administration: towards non-invasive glaucoma gene therapy.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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31 May 2018
Polymer-coated nanoparticles interacting with proteins and cells: focusing on the sign of the net charge
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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31 May 2018
Partial correction of cystic fibrosis defects with PLGA nanoparticles encapsulating curcumin
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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31 May 2018
Optimization of cell surface binding enhances efficiency and specificity of molecular conjugate gene delivery
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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31 May 2018
Advanced colloid-based systems for efficient delivery of drugs and diagnostic agents to the lymphatic tissues
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31 May 2018
Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: implications for therapy
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31 May 2018
Intranasal delivery of chitosan-siRNA nanoparticle formulation to the brain.
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28 November 2018
Biodistribution and pharmacokinetics of dapivirine-loaded nanoparticles after vaginal delivery in mice.
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28 November 2018
pH-sensitive nanoparticles of curcumin-celecoxib combination: evaluating drug synergy in ulcerative colitis model.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 November 2018
Selective nanovector mediated treatment of activated proinflammatory microglia/macrophages in spinal cord injury.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 November 2018
A window onto siRNA delivery.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 November 2018
Rapid lymph accumulation of polystyrene nanoparticles following pulmonary administration.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 November 2018
Nanoparticle-mediated delivery of pioglitazone enhances therapeutic neovascularization in a murine model of hindlimb ischemia.
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 November 2018
Goblet cell-targeting nanoparticles for oral insulin delivery and the influence of mucus on insulin transport
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 November 2018
Development of a mucoadhesive nanoparticulate drug delivery system for a targeted drug release in the bladder
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 November 2018
Chitosan-plasmid nanoparticle formulations for IM and SC delivery of recombinant FGF-2 and PDGF-BB or generation of antibodies
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 November 2018
Antisense oligonucleotide directed to human apolipoprotein B-100 reduces lipoprotein(a) levels and oxidized phospholipids on human apolipoprotein B-100 particles in lipoprotein(a) transgenic mice
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 November 2018
Mechanisms and optimization of in vivo delivery of lipophilic siRNAs.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 November 2018
Biodegradable polymeric microspheres and nanospheres for drug delivery in the peritoneum
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 November 2018
Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 November 2018
Enhanced tumour uptake of doxorubicin loaded poly(butyl cyanoacrylate) nanoparticles in mice bearing Dalton's lymphoma tumour
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451203
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28 November 2018
Widespread suppression of huntingtin with convection-enhanced delivery of siRNA
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31 March 2020
A PEDF N-terminal peptide protects the retina from ischemic injury when delivered in PLGA nanospheres
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Crossref
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https://api.crossref.org/works/10.1038%2FNRD4503
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31 March 2020
Subcutaneous and intravenous delivery of diagnostic agents to the lymphatic system: applications in lymphoscintigraphy and indirect lymphography
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Crossref
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31 March 2020
Distribution and elimination of poly(methyl methacrylate) nanoparticles after subcutaneous administration to rats
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Crossref
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https://api.crossref.org/works/10.1038%2FNRD4503
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31 March 2020
Biodistribution of (125)I-labeled polymeric vaccine carriers after subcutaneous injection
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Crossref
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https://api.crossref.org/works/10.1038%2FNRD4503
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31 March 2020
Surface engineered nanospheres with enhanced drainage into lymphatics and uptake by macrophages of the regional lymph nodes
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Crossref
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https://api.crossref.org/works/10.1038%2FNRD4503
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31 March 2020
Antibody Targeting of Long-Circulating Lipidic Nanoparticles Does Not Increase Tumor Localization but Does Increase Internalization in Animal Models
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Crossref
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https://api.crossref.org/works/10.1038%2FNRD4503
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31 March 2020
Does a targeting ligand influence nanoparticle tumor localization or uptake?
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Crossref
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https://api.crossref.org/works/10.1038%2FNRD4503
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31 March 2020
Breaking down the barriers: siRNA delivery and endosome escape
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Crossref
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https://api.crossref.org/works/10.1038%2FNRD4503
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31 March 2020
Anti-tumor efficacy and biodistribution of intravenous polymeric micellar paclitaxel
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Crossref
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https://api.crossref.org/works/10.1038%2FNRD4503
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31 March 2020
A new approach to the oral administration of insulin and other peptide drugs
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Crossref
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https://api.crossref.org/works/10.1038%2FNRD4503
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31 March 2020
Identifiers
DOI
10.1038/NRD4503
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
152083
Dimensions Publication ID
1041612413
0 references
OpenCitations bibliographic resource ID
152083
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
152083
PMCID
4451203
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
152083
PubMed ID
25598505
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
152083
ResearchGate publication ID
271139653
0 references
Springer Nature article ID
10.1038/nrd4503
0 references
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