Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q26865486)
Watch
English
Factor XI as a target for antithrombotic therapy
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
PubMed
title
Factor XI as a target for antithrombotic therapy
(English)
1 reference
stated in
PubMed
author name string
Charles E. Bane
series ordinal
1
1 reference
stated in
Crossref
David Gailani
series ordinal
2
1 reference
stated in
Crossref
language of work or name
English
1 reference
stated in
PubMed
publication date
September 2014
1 reference
stated in
PubMed
published in
Drug Discovery Today
1 reference
stated in
PubMed
volume
19
1 reference
stated in
PubMed
issue
9
1 reference
stated in
PubMed
page(s)
1454-8
1 reference
stated in
PubMed
cites work
Defective thrombus formation in mice lacking coagulation factor XII
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
21 March 2017
Tetrahydroquinoline derivatives as potent and selective factor XIa inhibitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
21 March 2017
Clavatadine A, a natural product with selective recognition and irreversible inhibition of factor XIa
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
21 March 2017
Effects of factor IX or factor XI deficiency on ferric chloride-induced carotid artery occlusion in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
21 March 2017
A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
21 March 2017
Location of the disulfide bonds in human coagulation factor XI: the presence of tandem apple domains
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
21 March 2017
Factor XII inhibition reduces thrombus formation in a primate thrombosis model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
28 September 2017
Desmolaris, a novel factor XIa anticoagulant from the salivary gland of the vampire bat (Desmodus rotundus) inhibits inflammation and thrombosis in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
28 September 2017
Evidence for factor IX-independent roles for factor XIa in blood coagulation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
28 September 2017
Factor XI anion-binding sites are required for productive interactions with polyphosphate.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
28 September 2017
Novel oral anticoagulants: a review of new agents.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
28 September 2017
Congenital factor XI deficiency: an update.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
28 September 2017
Analysis of the factor XI variant Arg184Gly suggests a structural basis for factor IX binding to factor XIa
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
28 September 2017
Discovery of allosteric modulators of factor XIa by targeting hydrophobic domains adjacent to its heparin-binding site
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
28 September 2017
Sulfated pentagalloylglucoside is a potent, allosteric, and selective inhibitor of factor XIa
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
28 September 2017
A sequential mechanism for exosite-mediated factor IX activation by factor XIa
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
28 September 2017
Tissue factor pathway inhibitor: structure-function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
28 September 2017
Factor XI: hemostasis, thrombosis, and antithrombosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
28 September 2017
Activation of factor XI by products of prothrombin activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
28 September 2017
Coagulation factor XI as a novel target for antithrombotic treatment.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
28 September 2017
Structure and function of factor XI
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
28 September 2017
Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
28 September 2017
Role of the extrinsic pathway of blood coagulation in hemostasis and thrombosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
28 September 2017
Antithrombotic effect of antisense factor XI oligonucleotide treatment in primates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
31 May 2018
High levels of factor IX increase the risk of venous thrombosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
31 May 2018
Selective depletion of factor XI or factor XII with antisense oligonucleotides attenuates catheter thrombosis in rabbits.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
28 November 2018
Inhibition of the intrinsic coagulation pathway factor XI by antisense oligonucleotides: a novel antithrombotic strategy with lowered bleeding risk.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
28 November 2018
Levels of intrinsic coagulation factors and the risk of myocardial infarction among men: Opposite and synergistic effects of factors XI and XII.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
28 November 2018
Variable bleeding manifestations characterize different types of surgery in patients with severe factor XI deficiency enabling parsimonious use of replacement therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
28 November 2018
Synthesis, SAR exploration, and X-ray crystal structures of factor XIa inhibitors containing an alpha-ketothiazole arginine.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167190
retrieved
28 November 2018
High levels of coagulation factor XI as a risk factor for venous thrombosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24886766
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Elevated factor XI activity levels are associated with an increased odds ratio for cerebrovascular events
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24886766
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Synthesis and in vitro biological evaluation of aryl boronic acids as potential inhibitors of factor XIa
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24886766
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Reduced incidence of ischemic stroke in patients with severe factor XI deficiency
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24886766
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Patients with severe factor XI deficiency have a reduced incidence of deep-vein thrombosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24886766
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A small-molecule factor XIa inhibitor produces antithrombotic efficacy with minimal bleeding time prolongation in rabbits
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24886766
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.DRUDIS.2014.05.018
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2437848
OpenCitations bibliographic resource ID
2437848
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2437848
PMC publication ID
4167190
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2437848
PubMed publication ID
24886766
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2437848
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
