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Nucleic Acid aptamers: new methods for selection, stabilization, and application in biomedical science
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title
Nucleic Acid aptamers: new methods for selection, stabilization, and application in biomedical science
(English)
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main subject
biomedicine
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inferred from title
author name string
Hoon Young Kong
series ordinal
1
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Crossref
Jonghoe Byun
series ordinal
2
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Crossref
language of work or name
English
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PubMed
publication date
November 2013
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PubMed
published in
Biomolecules & therapeutics
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PubMed
volume
21
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PubMed
issue
6
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stated in
PubMed
page(s)
423-34
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PubMed
cites work
Nucleic acid aptamers: an emerging frontier in cancer therapy
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Intra-accumbens injection of a dopamine aptamer abates MK-801-induced cognitive dysfunction in a model of schizophrenia
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CS-SELEX Generates High-Affinity ssDNA Aptamers as Molecular Probes for Hepatitis C Virus Envelope Glycoprotein E2
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An aptamer-siRNA chimera silences the eukaryotic elongation factor 2 gene and induces apoptosis in cancers expressing αvβ3 integrin.
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Selection of DNA aptamers against epithelial cell adhesion molecule for cancer cell imaging and circulating tumor cell capture
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Functional in vivo delivery of multiplexed anti-HIV-1 siRNAs via a chemically synthesized aptamer with a sticky bridge
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Targeted quantum dots fluorescence probes functionalized with aptamer and peptide for transferrin receptor on tumor cells
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Synthesis and radiolabeling of chelator-RNA aptamer bioconjugates with copper-64 for targeted molecular imaging
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A smart magnetic resonance imaging contrast agent responsive to adenosine based on a DNA aptamer-conjugated gadolinium complex
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28 September 2017
A nucleolin-targeted multimodal nanoparticle imaging probe for tracking cancer cells using an aptamer
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28 September 2017
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28 September 2017
Inhibition of von Willebrand factor-mediated platelet activation and thrombosis by the anti-von Willebrand factor A1-domain aptamer ARC1779.
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28 September 2017
Selection and elution of aptamers using nanoporous sol-gel arrays with integrated microheaters
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28 September 2017
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28 September 2017
Generating aptamers for recognition of virus-infected cells
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28 September 2017
Micromagnetic selection of aptamers in microfluidic channels
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28 September 2017
Cell-specific induction of apoptosis by rationally designed bivalent aptamer-siRNA transcripts silencing eukaryotic elongation factor 2.
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28 September 2017
Selecting aptamers for a glycoprotein through the incorporation of the boronic acid moiety
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28 September 2017
Assembling OX40 aptamers on a molecular scaffold to create a receptor-activating aptamer
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28 September 2017
Systematic analysis of enzymatic DNA polymerization using oligo-DNA templates and triphosphate analogs involving 2',4'-bridged nucleosides
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28 September 2017
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28 September 2017
Competitive FRET-aptamer-based detection of methylphosphonic acid, a common nerve agent metabolite
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28 September 2017
Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice.
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28 September 2017
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28 September 2017
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28 September 2017
One-step selection of Vaccinia virus-binding DNA aptamers by MonoLEX
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28 September 2017
Modified DNA aptamer that binds the (R)-isomer of a thalidomide derivative with high enantioselectivity
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28 September 2017
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28 September 2017
Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras
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28 September 2017
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28 September 2017
Aptamer mediated siRNA delivery
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28 September 2017
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28 September 2017
Tumor targeting by an aptamer
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28 September 2017
A microfluidic SELEX prototype
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28 September 2017
In vitro selection of DNA aptamers binding ethanolamine
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28 September 2017
Capillary electrophoresis-SELEX selection of aptamers with affinity for HIV-1 reverse transcriptase
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28 September 2017
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28 September 2017
Nonequilibrium capillary electrophoresis of equilibrium mixtures: a universal tool for development of aptamers.
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28 September 2017
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28 September 2017
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 September 2017
Application of locked nucleic acids to improve aptamer in vivo stability and targeting function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 September 2017
Molecular imaging of proteolytic activity in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 September 2017
GnRH binding RNA and DNA Spiegelmers: a novel approach toward GnRH antagonism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 September 2017
Boron-containing aptamers to ATP.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 September 2017
Generation of species cross-reactive aptamers using "toggle" SELEX.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 September 2017
Systematic evolution of a DNA aptamer binding to rat brain tumor microvessels. selective targeting of endothelial regulatory protein pigpen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 September 2017
In vitro selection of aptamers that act with Zn2+.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 September 2017
Effect of oligodeoxynucleotide thrombin aptamer on thrombin inhibition by heparin cofactor II and antithrombin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 September 2017
Towards the selection of phosphorothioate aptamers optimizing in vitro selection steps with phosphorothioate nucleotides.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 September 2017
In vitro selection of novel RNA ligands that bind human cytomegalovirus and block viral infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 September 2017
Aptamers containing thymidine 3'-O-phosphorodithioates: synthesis and binding to nuclear factor-kappaB.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 September 2017
Aptamers: an emerging class of molecules that rival antibodies in diagnostics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 September 2017
2'-Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 September 2017
Mirror-design of L-oligonucleotide ligands binding to L-arginine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 September 2017
Mirror-image RNA that binds D-adenosine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 September 2017
Bioactive and nuclease-resistant L-DNA ligand of vasopressin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 September 2017
Construction and initial characterization of a mouse-human chimeric anti-TNF antibody
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 September 2017
DNA-like double helix formed by peptide nucleic acid
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 September 2017
High-affinity ssDNA inhibitors of the reverse transcriptase of type 1 human immunodeficiency virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 September 2017
The application of a modified nucleotide in aptamer selection: novel thrombin aptamers containing 5-(1-pentynyl)-2'-deoxyuridine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 September 2017
High-resolution molecular discrimination by RNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 September 2017
Novel approach to specific growth factor inhibition in vivo: antagonism of platelet-derived growth factor in glomerulonephritis by aptamers.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
31 May 2018
Effect of BAX499 aptamer on tissue factor pathway inhibitor function and thrombin generation in models of hemophilia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 November 2018
Inhibition of HIV-1 protease expression in T cells owing to DNA aptamer-mediated specific delivery of siRNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 November 2018
Preculture of PBMCs at high cell density increases sensitivity of T-cell responses, revealing cytokine release by CD28 superagonist TGN1412.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 November 2018
Quantum dot-aptamer nanoprobes for recognizing and labeling influenza A virus particles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 November 2018
Study on suitability of KOD DNA polymerase for enzymatic production of artificial nucleic acids using base/sugar modified nucleoside triphosphates.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 November 2018
Transcription and reverse transcription of artificial nucleic acids involving backbone modification by template-directed DNA polymerase reactions.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 November 2018
Locked nucleic acid aptamers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 November 2018
Efficient enzymatic synthesis of LNA-modified DNA duplexes using KOD DNA polymerase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 November 2018
Smart “Turn-on” Magnetic Resonance Contrast Agents Based on Aptamer-Functionalized Superparamagnetic Iron Oxide Nanoparticles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 November 2018
Improved sensitivity and physical properties of sol-gel protein chips using large-scale material screening and selection.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 November 2018
Substrate properties of C5-substituted pyrimidine 2'-deoxynucleoside 5'-triphosphates for thermostable DNA polymerases during PCR.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 November 2018
Preclinical and phase 1A clinical evaluation of an anti-VEGF pegylated aptamer (EYE001) for the treatment of exudative age-related macular degeneration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 November 2018
Automated RNA selection.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879913
retrieved
28 November 2018
An aptamer-doxorubicin physical conjugate as a novel targeted drug-delivery platform
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24404332
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Local tolerance and systemic safety of pegaptanib sodium in the dog and rabbit
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24404332
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Non-SELEX selection of aptamers
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24404332
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Synthesis of mixed ribo/deoxyribopolynucleotides by mutant T7 RNA polymerase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24404332
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
RNA aptamers that bind flavin and nicotinamide redox cofactors
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24404332
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.4062/BIOMOLTHER.2013.085
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1856419
Fatcat ID
release_cfxgulgrajbjtirjaaoc3m4wni
0 references
OpenCitations bibliographic resource ID
1856419
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1856419
PMCID
3879913
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1856419
PubMed ID
24404332
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1856419
ResearchGate publication ID
259632239
0 references
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