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The genomic stability of induced pluripotent stem cells
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PubMed
title
The genomic stability of induced pluripotent stem cells
(English)
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author name string
Zhao Chen
series ordinal
1
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stated in
Crossref
Tongbiao Zhao
series ordinal
2
1 reference
stated in
Crossref
Yang Xu
series ordinal
3
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stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
April 2012
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stated in
PubMed
published in
Protein & Cell
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stated in
PubMed
volume
3
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stated in
PubMed
issue
4
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stated in
PubMed
page(s)
271-7
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stated in
PubMed
cites work
Modelling schizophrenia using human induced pluripotent stem cells
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LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress
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21 March 2017
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
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21 March 2017
Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients
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21 March 2017
Direct cell reprogramming is a stochastic process amenable to acceleration
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Disease-specific induced pluripotent stem cells
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Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing
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Selective blockade of microRNA processing by Lin28
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Core transcriptional regulatory circuitry in human embryonic stem cells
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Induction of pluripotent stem cells from adult human fibroblasts by defined factors
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21 March 2017
Induced pluripotent stem cell lines derived from human somatic cells
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21 March 2017
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
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Embryonic stem cell lines derived from human blastocysts
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Generation of germline-competent induced pluripotent stem cells
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Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
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21 March 2017
The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
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Immortalization eliminates a roadblock during cellular reprogramming into iPS cells
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Reprogramming of human somatic cells to pluripotency with defined factors
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Nanog transforms NIH3T3 cells and targets cell-type restricted genes
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21 March 2017
The pluripotency homeobox gene NANOG is expressed in human germ cell tumors
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p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression
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21 March 2017
Multipotent cell lineages in early mouse development depend on SOX2 function
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21 March 2017
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
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21 March 2017
Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
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21 March 2017
Epigenetic memory in induced pluripotent stem cells
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Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells
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7 April 2017
Immunogenicity of induced pluripotent stem cells
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7 April 2017
Somatic coding mutations in human induced pluripotent stem cells
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7 April 2017
Modelling the long QT syndrome with induced pluripotent stem cells
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7 April 2017
A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells
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7 April 2017
Patient-specific induced pluripotent stem-cell models for long-QT syndrome
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7 April 2017
Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells
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7 April 2017
Suppression of induced pluripotent stem cell generation by the p53-p21 pathway
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7 April 2017
A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity
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7 April 2017
The Ink4/Arf locus is a barrier for iPS cell reprogramming
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7 April 2017
Linking the p53 tumour suppressor pathway to somatic cell reprogramming
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Induced pluripotent stem cells from a spinal muscular atrophy patient
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Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes
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7 April 2017
Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
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Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
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p53: puzzle and paradigm
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Context-dependent enhancement of induced pluripotent stem cell reprogramming by silencing Puma
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Diseases in a dish: modeling human genetic disorders using induced pluripotent cells
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Copy number variation and selection during reprogramming to pluripotency
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Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome
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Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome
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Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture
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Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation.
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Reprogramming of human primary somatic cells by OCT4 and chemical compounds
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Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules.
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28 September 2017
Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome
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28 September 2017
Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells
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28 September 2017
Generation of induced pluripotent stem cells from newborn marmoset skin fibroblasts
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28 September 2017
Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer
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28 September 2017
p53 and stem cells: new developments and new concerns
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28 September 2017
A chemical platform for improved induction of human iPSCs
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28 September 2017
A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog
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28 September 2017
SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas
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28 September 2017
Sox2 is dispensable for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells
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28 September 2017
Clone- and gene-specific aberrations of parental imprinting in human induced pluripotent stem cells
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Senescence impairs successful reprogramming to pluripotent stem cells
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Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs.
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28 September 2017
Adult mice generated from induced pluripotent stem cells
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28 September 2017
iPS cells produce viable mice through tetraploid complementation
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28 September 2017
Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells
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28 September 2017
iPS cells can support full-term development of tetraploid blastocyst-complemented embryos
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28 September 2017
Expression of an exogenous human Oct-4 promoter identifies tumor-initiating cells in osteosarcoma
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Lin28 promotes transformation and is associated with advanced human malignancies
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Generation of induced pluripotent stem cell lines from Tibetan miniature pig.
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28 September 2017
Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds
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28 September 2017
A high-efficiency system for the generation and study of human induced pluripotent stem cells
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28 September 2017
Reprogramming of neural progenitor cells into induced pluripotent stem cells in the absence of exogenous Sox2 expression
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28 September 2017
Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors
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28 September 2017
Reprogramming of pancreatic beta cells into induced pluripotent stem cells
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28 September 2017
Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency
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28 September 2017
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28 September 2017
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28 September 2017
Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells.
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28 September 2017
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Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues
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28 September 2017
The biology of the mammalian Krüppel-like family of transcription factors
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28 September 2017
Mouse models of human disease. Part II: recent progress and future directions
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28 September 2017
A human iPSC model of Hutchinson Gilford Progeria reveals vascular smooth muscle and mesenchymal stem cell defects
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Mutant p53 facilitates somatic cell reprogramming and augments the malignant potential of reprogrammed cells
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Mouse models of human disease. Part I: techniques and resources for genetic analysis in mice
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Mice generated from tetraploid complementation competent iPS cells show similar developmental features as those from ES cells but are prone to tumorigenesis.
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Brief report: combined chemical treatment enables Oct4-induced reprogramming from mouse embryonic fibroblasts
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Identification and Classification of Chromosomal Aberrations in Human Induced Pluripotent Stem Cells
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Two Supporting Factors Greatly Improve the Efficiency of Human iPSC Generation
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Generation of Rat and Human Induced Pluripotent Stem Cells by Combining Genetic Reprogramming and Chemical Inhibitors
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based on heuristic
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Oct-3/4 is a dose-dependent oncogenic fate determinant
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Identifiers
DOI
10.1007/S13238-012-2922-8
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Dimensions Publication ID
1046640974
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PMC publication ID
4875480
1 reference
stated in
PubMed
PubMed publication ID
22528751
1 reference
stated in
PubMed
ResearchGate publication ID
224821300
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