(Q27000255)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25973139%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

review article

1 reference

title

Alzheimer's pathogenesis and its link to the mitochondrion (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25973139%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

1 reference

3 references

25 April 2019

12 October 2019

1 reference

12 October 2019

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25973139%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

Elena Caldarazzo Ienco

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25973139%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

Gabriele Siciliano

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25973139%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

Ubaldo Bonuccelli

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25973139%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

Daniele Orsucci

1 reference

ORCID Public Data File 2021

author name string

D Orsucci

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25973139%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

M Mancuso

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25973139%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

language of work or name

1 reference

20 April 2015

3 references

25 April 2019

12 October 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25973139%20AND%20SRC:MED&resulttype=core&format=json

Oxidative Medicine and Cellular Longevity

8 March 2020

published in

4 references

25 April 2019

12 October 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25973139%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

volume

2015

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25973139%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

page(s)

803942

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25973139%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

8 March 2020

copyright license

2 references

25 April 2019

on focus list of Wikimedia project

12 October 2019

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

May "mitochondrial eve" and mitochondrial haplogroups play a role in neurodegeneration and Alzheimer's disease?

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Protein aggregation in the brain: the molecular basis for Alzheimer's and Parkinson's diseases

21 March 2017

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Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

21 March 2017

1 reference

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Amyloid plaque core protein in Alzheimer disease and Down syndrome

21 March 2017

1 reference

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

21 March 2017

1 reference

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Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brain

21 March 2017

1 reference

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Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

21 March 2017

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Trafficking and proteolytic processing of APP

21 March 2017

1 reference

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The microtubule-associated protein tau is extensively modified with O-linked N-acetylglucosamine

21 March 2017

1 reference

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Mitochondrial DNA sequence variation and neurodegeneration

21 March 2017

1 reference

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Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B

21 March 2017

1 reference

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Translocation of proteins into mitochondria

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Mild cognitive impairment as a diagnostic entity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Mitochondrial respiratory-chain diseases

7 April 2017

1 reference

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Mitochondrial diseases in man and mouse

7 April 2017

1 reference

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Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release

7 April 2017

1 reference

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Vascular factors and mitochondrial dysfunction: a central role in the pathogenesis of Alzheimer's disease.

28 September 2017

1 reference

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OXPHOS mutations and neurodegeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Presenilin-1 adopts pathogenic conformation in normal aging and in sporadic Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Is amyloid binding alcohol dehydrogenase a drug target for treating Alzheimer's disease?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

No consistent evidence for association between mtDNA variants and Alzheimer disease

28 September 2017

1 reference

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Membrane trafficking pathways in Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Coenzyme Q10 decreases amyloid pathology and improves behavior in a transgenic mouse model of Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

The role of mitochondria in neurodegenerative diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

The acetylation of tau inhibits its function and promotes pathological tau aggregation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Amyloid-β/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Clinical features and pathogenesis of Alzheimer's disease: involvement of mitochondria and mitochondrial DNA.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease

28 September 2017

1 reference

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Oxidative stress in Alzheimer disease: a possibility for prevention

28 September 2017

1 reference

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Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology

28 September 2017

1 reference

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The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Functions and dysfunctions of mitochondrial dynamics

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Mitochondrial cascade hypothesis of Alzheimer's disease: myth or reality?

28 September 2017

1 reference

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Mitochondrial oxidative stress causes hyperphosphorylation of tau.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Vascular oxidative stress in Alzheimer disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Mitochondrial morphology and distribution in mammalian cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Oxidative stress in brain aging, neurodegenerative and vascular diseases: an overview.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Mitochondria take center stage in aging and neurodegeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Vitamin E and donepezil for the treatment of mild cognitive impairment

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

A modified beta-amyloid hypothesis: intraneuronal accumulation of the beta-amyloid peptide--the first step of a fatal cascade

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Mitochondrial proteins in neuronal degeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Mitochondria dysfunction of Alzheimer's disease cybrids enhances Abeta toxicity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Essentials of the Proper Diagnoses of Mild Cognitive Impairment, Dementia, and Major Subtypes of Dementia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Neurofibrillary tangles, amyloid, and memory in aging and mild cognitive impairment

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

γ-Secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Insertion of hydrophobic membrane proteins into the inner mitochondrial membrane--a guided tour

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Current concepts in mild cognitive impairment

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Mitochondria, oxygen free radicals, and apoptosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

The rotary machine in the cell, ATP synthase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Glutathione, oxidative stress and neurodegeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Inherent abnormalities in energy metabolism in Alzheimer disease. Interaction with cerebrovascular compromise

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Intraneuronal Abeta42 accumulation in human brain.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Cybrids in Alzheimer's disease: a cellular model of the disease?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Early detection of Alzheimer's disease: a statistical approach using positron emission tomographic data

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Puerarin protects Alzheimer's disease neuronal cybrids from oxidant-stress induced apoptosis by inhibiting pro-death signaling pathways

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Nerve growth factor attenuates oxidant-induced β-amyloid neurotoxicity in sporadic Alzheimer's disease cybrids

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Alterations in muscarinic receptor-coupled phosphoinositide hydrolysis and AP-1 activation in Alzheimer's disease cybrid cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Thickening of the basement membrane of cortical capillaries in Alzheimer's disease.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Microtubule-associated protein tau. A component of Alzheimer paired helical filaments

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

Genetics of Alzheimer's Disease and Frontotemporal Dementia.

31 May 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F803942

Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F803942

Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F803942

Mitochondrial abnormalities in Alzheimer brain: mechanistic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F803942

Evolutionary biology: essence of mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F803942

A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F803942

Rapid activation of heat shock factor-1 DNA binding by H2O2 and modulation by glutathione in human neuroblastoma and Alzheimer's disease cybrid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F803942

Cognitive impairment and increased Aβ levels induced by paraquat exposure are attenuated by enhanced removal of mitochondrial H(2)O(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F803942

Analysis of European mitochondrial haplogroups with Alzheimer disease risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F803942

Mitochondrial DNA haplogroups and susceptibility to AD and dementia with Lewy bodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F803942

Lack of association between mtDNA haplogroups and Alzheimer's disease in Tuscany.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F803942

Increased plaque burden in brains of APP mutant MnSOD heterozygous knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F803942

Reduction in mitochondrial superoxide dismutase modulates Alzheimer's disease-like pathology and accelerates the onset of behavioral changes in human amyloid precursor protein transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F803942

Mitochondrial respiratory inhibition and oxidative stress elevate beta-secretase (BACE1) proteins and activity in vivo in the rat retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F803942

Mitochondrial β-amyloid in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F803942

Quinones facilitate the self-assembly of the phosphorylated tubulin binding region of tau into fibrillar polymers

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F803942

Cerebrovascular muscle atrophy is a feature of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F803942

Atherosclerosis of cerebral arteries in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F803942

Cerebral hypoperfusion and clinical onset of dementia: the Rotterdam Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F803942

Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F803942

Mitochondria DNA deletions in atherosclerotic hypoperfused brain microvessels as a primary target for the development of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F803942

18F-THK523: a novel in vivo tau imaging ligand for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F803942

Mitochondrial DNA haplogroups and APOE4 allele are non-independent variables in sporadic Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F803942

Mitochondrial damage in Alzheimer's disease varies with apolipoprotein E genotype.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417983

28 November 2018

1 reference

12 December 2020

Phylogenetic analysis of the mitochondrial genome indicates significant differences between patients with Alzheimer disease and controls in a French-Canadian founder population

1 reference

12 December 2020

Common mechanisms in neurodegeneration

1 reference

12 December 2020

1 reference

12 December 2020

Does the mitochondrial genome play a role in the etiology of Alzheimer's disease?

1 reference

12 December 2020

The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain

1 reference

12 December 2020

Identifiers

DOI

10.1155/2015/803942

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25973139%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25973139%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

PubMed publication ID

25973139

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25973139%20AND%20SRC:MED&resulttype=core&format=json