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KNL1: bringing order to the kinetochore
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scholarly article
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PubMed
title
KNL1: bringing order to the kinetochore
(English)
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main subject
kinetochore
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author name string
Gina V. Caldas
series ordinal
1
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stated in
Crossref
Jennifer G. DeLuca
series ordinal
2
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stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
June 2014
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stated in
PubMed
published in
Chromosoma
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stated in
PubMed
volume
123
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stated in
PubMed
issue
3
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stated in
PubMed
page(s)
169-81
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stated in
PubMed
cites work
The spindle assembly checkpoint
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stated in
PubMed Central
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21 March 2017
Modularity and functional plasticity of scaffold proteins as p(l)acemakers in cell signaling
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21 March 2017
Structural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interaction
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PubMed Central
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21 March 2017
Induced ectopic kinetochore assembly bypasses the requirement for CENP-A nucleosomes
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PubMed Central
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21 March 2017
Bub1 regulates chromosome segregation in a kinetochore-independent manner
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
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21 March 2017
KNL1 and the CENP-H/I/K complex coordinately direct kinetochore assembly in vertebrates
1 reference
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PubMed Central
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21 March 2017
Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1
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PubMed Central
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21 March 2017
The conserved KMN network constitutes the core microtubule-binding site of the kinetochore
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PubMed Central
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21 March 2017
Hec1 sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint control
1 reference
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PubMed Central
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21 March 2017
The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation.
1 reference
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PubMed Central
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21 March 2017
Intrinsically unstructured proteins and their functions
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PubMed Central
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21 March 2017
Human Zwint-1 specifies localization of Zeste White 10 to kinetochores and is essential for mitotic checkpoint signaling
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PubMed Central
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21 March 2017
A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension
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21 March 2017
Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression
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PubMed Central
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21 March 2017
The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint
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PubMed Central
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21 March 2017
hNuf2 inhibition blocks stable kinetochore-microtubule attachment and induces mitotic cell death in HeLa cells
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PubMed Central
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21 March 2017
Frequent expression of new cancer/testis gene D40/AF15q14 in lung cancers of smokers
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21 March 2017
Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2
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21 March 2017
Spindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3, and CENP-E, independently of its kinase activity
1 reference
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PubMed Central
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21 March 2017
Functional analysis of kinetochore assembly in Caenorhabditis elegans.
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21 March 2017
AF15q14, a novel partner gene fused to the MLL gene in an acute myeloid leukaemia with a t(11;15)(q23;q14)
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21 March 2017
The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase
1 reference
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PubMed Central
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21 March 2017
Bub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signaling
1 reference
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PubMed Central
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21 March 2017
CENP-T provides a structural platform for outer kinetochore assembly
1 reference
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PubMed Central
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21 March 2017
Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site
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21 March 2017
The Ndc80 kinetochore complex forms oligomeric arrays along microtubules
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PubMed Central
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21 March 2017
Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex
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PubMed Central
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21 March 2017
Chromosomes can congress to the metaphase plate before biorientation
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PubMed Central
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21 March 2017
The spindle-assembly checkpoint in space and time
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21 March 2017
CENP-T proteins are conserved centromere receptors of the Ndc80 complex
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PubMed Central
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21 March 2017
Cnn1 inhibits the interactions between the KMN complexes of the yeast kinetochore
1 reference
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PubMed Central
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21 March 2017
Roles for the conserved spc105p/kre28p complex in kinetochore-microtubule binding and the spindle assembly checkpoint
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PubMed Central
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21 March 2017
The fission yeast kinetochore component Spc7 associates with the EB1 family member Mal3 and is required for kinetochore-spindle association
1 reference
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PubMed Central
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21 March 2017
Interactions between Centromere Complexes inSaccharomyces cerevisiae
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21 March 2017
CENP-E is a plus end-directed kinetochore motor required for metaphase chromosome alignment
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
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21 March 2017
Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores
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PubMed Central
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21 March 2017
Extended disordered proteins: targeting function with less scaffold
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21 March 2017
Molecular analysis of core kinetochore composition and assembly in Drosophila melanogaster
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21 March 2017
The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint
1 reference
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21 March 2017
Association of spindle assembly checkpoint component XMAD2 with unattached kinetochores
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21 March 2017
Phosphorylation of H2A by Bub1 prevents chromosomal instability through localizing shugoshin
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21 March 2017
Kinetochore microtubule dynamics and attachment stability are regulated by Hec1
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7 April 2017
Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III
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7 April 2017
KNL1 facilitates phosphorylation of outer kinetochore proteins by promoting Aurora B kinase activity
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28 September 2017
Cyclin A regulates kinetochore microtubules to promote faithful chromosome segregation
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28 September 2017
Spindle assembly checkpoint proteins are positioned close to core microtubule attachment sites at kinetochores.
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28 September 2017
Modulation of allostery by protein intrinsic disorder
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28 September 2017
Tracking spindle checkpoint signals from kinetochores to APC/C.
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28 September 2017
The KMN protein network--chief conductors of the kinetochore orchestra
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28 September 2017
The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis
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28 September 2017
Cancer-Specific requirement for BUB1B/BUBR1 in human brain tumor isolates and genetically transformed cells
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28 September 2017
Intrinsically disordered proteins: a 10-year recap
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28 September 2017
Evolution and function of the mitotic checkpoint
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28 September 2017
Connecting up and clearing out: how kinetochore attachment silences the spindle assembly checkpoint.
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28 September 2017
Establishment of the vertebrate kinetochores
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28 September 2017
Microtubule binding by KNL-1 contributes to spindle checkpoint silencing at the kinetochore
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28 September 2017
Biophysics of mitosis
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28 September 2017
Structural organization of the kinetochore-microtubule interface
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28 September 2017
Spindle assembly checkpoint: the third decade
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28 September 2017
Spindle checkpoint silencing: PP1 tips the balance.
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28 September 2017
The CCAN complex: linking centromere specification to control of kinetochore-microtubule dynamics
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28 September 2017
Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase
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28 September 2017
The spatial arrangement of chromosomes during prometaphase facilitates spindle assembly
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28 September 2017
KNL1/Spc105 recruits PP1 to silence the spindle assembly checkpoint
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28 September 2017
The Ndc80 complex: integrating the kinetochore's many movements
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28 September 2017
The MIS12 complex is a protein interaction hub for outer kinetochore assembly
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28 September 2017
Aurora B phosphorylates spatially distinct targets to differentially regulate the kinetochore-microtubule interface
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28 September 2017
Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells
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28 September 2017
Finding the middle ground: how kinetochores power chromosome congression.
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28 September 2017
Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase
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PubMed Central
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28 September 2017
The kinetochore and the centromere: a working long distance relationship.
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28 September 2017
The life and miracles of kinetochores
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28 September 2017
Protein phosphatase 1 regulates exit from the spindle checkpoint in budding yeast
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28 September 2017
Intrakinetochore localization and essential functional domains of Drosophila Spc105.
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28 September 2017
Chromosome congression in the absence of kinetochore fibres
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28 September 2017
The Ndc80 kinetochore complex forms load-bearing attachments to dynamic microtubule tips via biased diffusion
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28 September 2017
Unattached kinetochores catalyze production of an anaphase inhibitor that requires a Mad2 template to prime Cdc20 for BubR1 binding
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
28 September 2017
Scaffold proteins and immune-cell signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
28 September 2017
Kinetochore attachments require an interaction between unstructured tails on microtubules and Ndc80(Hec1).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
28 September 2017
Allosteric signaling in the biotin repressor occurs via local folding coupled to global dampening of protein dynamics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
28 September 2017
CENP-E combines a slow, processive motor and a flexible coiled coil to produce an essential motile kinetochore tether
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
28 September 2017
Mechanisms of mitotic spindle assembly and function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
28 September 2017
Bub1 is a fission yeast kinetochore scaffold protein, and is sufficient to recruit other spindle checkpoint proteins to ectopic sites on chromosomes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
28 September 2017
Aurora kinase promotes turnover of kinetochore microtubules to reduce chromosome segregation errors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
28 September 2017
Intrinsic disorder is a common feature of hub proteins from four eukaryotic interactomes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
28 September 2017
Accumulation of Mad2-Cdc20 complex during spindle checkpoint activation requires binding of open and closed conformers of Mad2 in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
28 September 2017
Rod-Zw10-Zwilch: a key player in the spindle checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
28 September 2017
Kinetochore targeting of fission yeast Mad and Bub proteins is essential for spindle checkpoint function but not for all chromosome segregation roles of Bub1p
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
28 September 2017
Spindle checkpoint protein dynamics at kinetochores in living cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
28 September 2017
Dynamics of centromere and kinetochore proteins; implications for checkpoint signaling and silencing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
28 September 2017
KNL-1 directs assembly of the microtubule-binding interface of the kinetochore in C. elegans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
28 September 2017
CENP-E is essential for reliable bioriented spindle attachment, but chromosome alignment can be achieved via redundant mechanisms in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
28 September 2017
Chromosomal assignment of a novel human gene D40.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
28 September 2017
CENP-E function at kinetochores is essential for chromosome alignment.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
28 September 2017
MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC components
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
31 May 2018
Phosphoregulation of Spc105 by Mps1 and PP1 regulates Bub1 localization to kinetochores
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
31 May 2018
Spindle checkpoint silencing requires association of PP1 to both Spc7 and kinesin-8 motors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
31 May 2018
Constitutive Mad1 targeting to kinetochores uncouples checkpoint signalling from chromosome biorientation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
31 May 2018
Protein interaction domain mapping of human kinetochore protein Blinkin reveals a consensus motif for binding of spindle assembly checkpoint proteins Bub1 and BubR1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
31 May 2018
BubR1 N terminus acts as a soluble inhibitor of cyclin B degradation by APC/C(Cdc20) in interphase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
31 May 2018
The conserved Spc7 protein is required for spindle integrity and links kinetochore complexes in fission yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032621
retrieved
31 May 2018
Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1007%2FS00412-013-0446-5
retrieved
21 January 2018
The Mad2 spindle checkpoint protein has two distinct natively folded states
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1007%2FS00412-013-0446-5
retrieved
21 January 2018
Phosphodependent recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 kinase maintains the spindle checkpoint.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1007%2FS00412-013-0446-5
retrieved
21 January 2018
Integration of kinase and phosphatase activities by BUBR1 ensures formation of stable kinetochore-microtubule attachments.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1007%2FS00412-013-0446-5
retrieved
21 January 2018
A novel protein phosphatase 1-dependent spindle checkpoint silencing mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1007%2FS00412-013-0446-5
retrieved
21 January 2018
Two histone marks establish the inner centromere and chromosome bi-orientation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1007%2FS00412-013-0446-5
retrieved
21 January 2018
Smoothing molecular interactions: the "kinetic buffer" effect of intrinsically disordered proteins
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24310619
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1007/S00412-013-0446-5
0 references
Dimensions Publication ID
1037662087
0 references
Fatcat ID
release_fuw65rbmfbezrm46rfzft2ysca
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/fuw65rbmfbezrm46rfzft2ysca
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMC publication ID
4032621
1 reference
stated in
PubMed
PubMed publication ID
24310619
1 reference
stated in
PubMed
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