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Potential use of γ-secretase modulators in the treatment of Alzheimer disease
scientific article
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scholarly article
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title
Potential use of γ-secretase modulators in the treatment of Alzheimer disease
(English)
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main subject
Alzheimer's disease
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based on heuristic
inferred from title
author
Rudolph E. Tanzi
series ordinal
2
object named as
Rudolph E. Tanzi
1 reference
stated in
Crossref
Douglas R. Galasko
series ordinal
4
object named as
Douglas Galasko
1 reference
stated in
Crossref
author name string
Steven L. Wagner
series ordinal
1
1 reference
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Crossref
William C. Mobley
series ordinal
3
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Crossref
language of work or name
English
1 reference
stated in
PubMed
publication date
October 2012
1 reference
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PubMed
published in
Archives of Neurology
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stated in
PubMed
volume
69
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stated in
PubMed
issue
10
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stated in
PubMed
page(s)
1255-8
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PubMed
cites work
A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3747667
retrieved
21 March 2017
Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3747667
retrieved
7 April 2017
Modulation of gamma-secretase reduces beta-amyloid deposition in a transgenic mouse model of Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3747667
retrieved
28 September 2017
Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease: a randomized controlled trial
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3747667
retrieved
28 September 2017
Begacestat (GSI-953): a novel, selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase for the treatment of Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3747667
retrieved
28 September 2017
Presenilins: members of the gamma-secretase quartets, but part-time soloists too.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3747667
retrieved
28 September 2017
Effect of an inhibitor of 3-hydroxy-3-methyglutaryl coenzyme A reductase on serum lipoproteins and ubiquinone-10-levels in patients with familial hypercholesterolemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3747667
retrieved
28 September 2017
Reductions in beta-amyloid concentrations in vivo by the gamma-secretase inhibitors BMS-289948 and BMS-299897.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3747667
retrieved
28 November 2018
A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3747667
retrieved
28 November 2018
Identifiers
DOI
10.1001/ARCHNEUROL.2012.540
0 references
PMC publication ID
3747667
1 reference
stated in
PubMed
PubMed publication ID
22801784
1 reference
stated in
PubMed
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