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Ras family of small GTPases in immunity and inflammation
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scholarly article
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PubMed
title
Ras family of small GTPases in immunity and inflammation
(English)
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main subject
inflammation
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author name string
Derek S Johnson
series ordinal
1
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stated in
Crossref
Youhai H Chen
series ordinal
2
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Crossref
language of work or name
English
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stated in
PubMed
publication date
August 2012
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stated in
PubMed
published in
Current Opinion in Pharmacology
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PubMed
volume
12
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PubMed
issue
4
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PubMed
page(s)
458-63
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PubMed
cites work
RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
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21 March 2017
Induction of glucose metabolism in stimulated T lymphocytes is regulated by mitogen-activated protein kinase signaling
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PubMed Central
reference URL
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21 March 2017
Rap1 GTPase-activating protein SPA-1 negatively regulates cell adhesion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
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21 March 2017
RalB mobilizes the exocyst to drive cell migration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
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21 March 2017
The anti-inflammatory TIPE2 is an inhibitor of the oncogenic Ras.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
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28 September 2017
Differential regulation of primary and memory CD8 T cell immune responses by diacylglycerol kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
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28 September 2017
Ral GTPases regulate cell-mediated cytotoxicity in NK cells.
1 reference
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PubMed Central
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28 September 2017
Phospholipase D mediates nutrient input to mammalian target of rapamycin complex 1 (mTORC1).
1 reference
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PubMed Central
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28 September 2017
Grb2 regulates B-cell maturation, B-cell memory responses and inhibits B-cell Ca2+ signalling.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
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28 September 2017
Decreased diacylglycerol metabolism enhances ERK activation and augments CD8+ T cell functional responses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
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28 September 2017
Localized diacylglycerol-dependent stimulation of Ras and Rap1 during phagocytosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
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28 September 2017
Rap1b regulates B cell development, homing, and T cell-dependent humoral immunity
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
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28 September 2017
RalGDS couples growth factor signaling to Akt activation
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PubMed Central
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28 September 2017
Rapamycin, but not cyclosporine or FK506, alters natural killer cell function.
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PubMed Central
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28 September 2017
Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
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28 September 2017
Autoantibodies to the C-terminal subunit of RLIP76 induce oxidative stress and endothelial cell apoptosis in immune-mediated vascular diseases and atherosclerosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
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28 September 2017
Defective angiogenesis, endothelial migration, proliferation, and MAPK signaling in Rap1b-deficient mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
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28 September 2017
The Par polarity complex regulates Rap1- and chemokine-induced T cell polarization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
retrieved
28 September 2017
RalB GTPase-mediated activation of the IkappaB family kinase TBK1 couples innate immune signaling to tumor cell survival
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
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28 September 2017
Crucial functions of the Rap1 effector molecule RAPL in lymphocyte and dendritic cell trafficking
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
retrieved
28 September 2017
B-Raf contributes to sustained extracellular signal-regulated kinase activation associated with interleukin-2 production stimulated through the T cell receptor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
retrieved
28 September 2017
The Rap GTPases regulate integrin-mediated adhesion, cell spreading, actin polymerization, and Pyk2 tyrosine phosphorylation in B lymphocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
retrieved
28 September 2017
MAPK/ERK signaling in activated T cells inhibits CD95/Fas-mediated apoptosis downstream of DISC assembly
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
retrieved
28 September 2017
The GTPase Rap1 controls functional activation of macrophage integrin alphaMbeta2 by LPS and other inflammatory mediators
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
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28 September 2017
Rap1 is a potent activation signal for leukocyte function-associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
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28 September 2017
Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
retrieved
28 September 2017
Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
retrieved
31 May 2018
Rap1A-deficient T and B cells show impaired integrin-mediated cell adhesion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
retrieved
31 May 2018
Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
retrieved
31 May 2018
Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
retrieved
31 May 2018
Ral Isoforms Are Implicated in Fc R-Mediated Phagocytosis: Activation of Phospholipase D by RalA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
retrieved
28 November 2018
Effects of immunosuppressive drugs on purified human B cells: evidence supporting the use of MMF and rapamycin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
retrieved
28 November 2018
Distinct signaling mechanisms activate the target of rapamycin in response to different B-cell stimuli.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
retrieved
28 November 2018
A systems biology analysis of the Drosophila phagosome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
retrieved
28 November 2018
The sequential activity of the GTPases Rap1B and Cdc42 determines neuronal polarity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
retrieved
28 November 2018
A novel ERK-dependent signaling process that regulates interleukin-2 expression in a late phase of T cell activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374043
retrieved
28 November 2018
Regulation of Toll-like receptor-induced chemokine production in murine dendritic cells by mitogen-activated protein kinases
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22401931
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Characterization of the anti-inflammatory effect of FK-506 on human mast cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22401931
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Maintenance of human T cell anergy: blocking of IL-2 gene transcription by activated Rap1
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22401931
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A role for mammalian target of rapamycin in regulating T cell activation versus anergy
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22401931
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.COPH.2012.02.003
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
5096054
OpenCitations bibliographic resource ID
5096054
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
5096054
PMCID
3374043
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
5096054
PubMed ID
22401931
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
5096054
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