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19 March 2020

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1 December 2020

Human endogenous retrovirus K and cancer: Innocent bystander or tumorigenic accomplice? (English)

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1 December 2020

Human endogenous retrovirus K

object named as

Human endogenous retrovirus K

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2

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19 March 2020

Stefan Ambs

4

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19 March 2020

Sharon A Glynn

6

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19 March 2020

author name string

Feng Wang-Johanning

3

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19 March 2020

Ronan F Downey

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19 March 2020

Francis J Giles

5

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19 March 2020

language of work or name

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17 June 2014

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International Journal of Cancer

19 March 2020

15 September 2015

1 reference

1 December 2020

6 references

3 April 2019

30 June 2019

3 November 2019

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19 March 2020

1 December 2020

137

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19 March 2020

issue

6

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19 March 2020

page(s)

1249-1257

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Creative Commons Attribution

19 March 2020

copyright license

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3 April 2019

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cites work

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The viruses in all of us: characteristics and biological significance of human endogenous retrovirus sequences

21 January 2018

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The evolutionary dynamics of human endogenous retroviral families

21 January 2018

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Retroelements and the human genome: new perspectives on an old relation

21 January 2018

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Identification, characterization, and comparative genomic distribution of the HERV-K (HML-2) group of human endogenous retroviruses

21 January 2018

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Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis

21 January 2018

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Identification of an envelope protein from the FRD family of human endogenous retroviruses (HERV-FRD) conferring infectivity and functional conservation among simians

21 January 2018

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Endogenous retroviral LTRs as promoters for human genes: a critical assessment.

21 January 2018

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Molecular mechanisms mediated by human endogenous retroviruses (HERVs) in autoimmunity

21 January 2018

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The human endogenous retrovirus link between genes and environment in multiple sclerosis and in multifactorial diseases associating neuroinflammation

21 January 2018

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GNbAC1, a humanized monoclonal antibody against the envelope protein of multiple sclerosis-associated endogenous retrovirus: a first-in-humans randomized clinical study

21 January 2018

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Expression and activation by Epstein Barr virus of human endogenous retroviruses-W in blood cells and astrocytes: inference for multiple sclerosis

21 January 2018

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Comprehensive analysis of human endogenous retrovirus group HERV-W locus transcription in multiple sclerosis brain lesions by high-throughput amplicon sequencing

21 January 2018

1 reference

HERV-K hypomethylation in ovarian clear cell carcinoma is associated with a poor prognosis and platinum resistance.

21 January 2018

1 reference

Expression of multiple human endogenous retrovirus surface envelope proteins in ovarian cancer.

21 January 2018

1 reference

Expression of human endogenous retrovirus K in melanomas and melanoma cell lines

21 January 2018

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Quantitation of HERV-K env gene expression and splicing in human breast cancer

21 January 2018

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Human endogenous retrovirus K triggers an antigen-specific immune response in breast cancer patients.

21 January 2018

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Human endogenous retrovirus (HERV-K) reverse transcriptase as a breast cancer prognostic marker

21 January 2018

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Insertional polymorphisms of endogenous HERV-K113 and HERV-K115 retroviruses in breast cancer patients and age-matched controls

21 January 2018

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Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer

21 January 2018

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Selective changes of retroelement expression in human prostate cancer

21 January 2018

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Detection of Human Endogenous Retrovirus K (HERV-K) Transcripts in Human Prostate Cancer Cell Lines.

21 January 2018

1 reference

Human endogenous retrovirus K (HML-2) elements in the plasma of people with lymphoma and breast cancer

21 January 2018

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Expression of a human endogenous retrovirus, HERV-K, in the blood cells of leukemia patients

21 January 2018

1 reference

Two groups of endogenous MMTV related retroviral env transcripts expressed in human tissues

21 January 2018

1 reference

Type 1 HERV-K genome is spliced into subgenomic transcripts in the human breast tumor cell line T47D.

21 January 2018

1 reference

Immunotherapeutic potential of anti-human endogenous retrovirus-K envelope protein antibodies in targeting breast tumors

21 January 2018

1 reference

Expression of Human Endogenous Retrovirus Type K Envelope Protein is a Novel Candidate Prognostic Marker for Human Breast Cancer

21 January 2018

1 reference

Human endogenous retrovirus type K antibodies and mRNA as serum biomarkers of early-stage breast cancer.

21 January 2018

1 reference

Truncated ETV1, fused to novel tissue-specific genes, and full-length ETV1 in prostate cancer.

21 January 2018

1 reference

Expression of human endogenous retrovirus (HERV-K) in chronic myeloid leukemia

21 January 2018

1 reference

Reactivity of monoclonal antibodies established against a recombinant human endogenous retrovirus-K (HERV-K) envelope protein

21 January 2018

1 reference

Epstein-Barr virus transactivates the human endogenous retrovirus HERV-K18 that encodes a superantigen

21 January 2018

1 reference

EBV LMP-2A employs a novel mechanism to transactivate the HERV-K18 superantigen through its ITAM.

21 January 2018

1 reference

Human endogenous retrovirus IDDMK(1,2)22 and mouse mammary tumor virus superantigens differ in their ability to stimulate murine T cell hybridomas

21 January 2018

1 reference

Autoantibodies to human endogenous retrovirus-K are frequently detected in health and disease and react with multiple epitopes.

21 January 2018

1 reference

Identification of a melanoma marker derived from melanoma-associated endogenous retroviruses.

21 January 2018

1 reference

The role of human endogenous retroviruses in melanoma

21 January 2018

1 reference

Human endogenous retrovirus K (HERV-K) rec mRNA is expressed in primary melanoma but not in benign naevi or normal skin

21 January 2018

1 reference

Transcriptional profiling of human endogenous retrovirus group HERV-K(HML-2) loci in melanoma

21 January 2018

1 reference

Human endogenous retrovirus K solo-LTR formation and insertional polymorphisms: implications for human and viral evolution

21 January 2018

1 reference

Genomewide screening reveals high levels of insertional polymorphism in the human endogenous retrovirus family HERV-K(HML2): implications for present-day activity

21 January 2018

1 reference

Human endogenous retroviruses and cancer: causality and therapeutic possibilities

21 January 2018

1 reference

Hypermutation of an ancient human retrovirus by APOBEC3G

21 January 2018

1 reference

DNA methylation in cancer: too much, but also too little

21 January 2018

1 reference

Custom human endogenous retroviruses dedicated microarray identifies self-induced HERV-W family elements reactivated in testicular cancer upon methylation control.

21 January 2018

1 reference

Regulation of human endogenous retrovirus-K expression in melanomas by CpG methylation

21 January 2018

1 reference

Distinctive patterns of age-dependent hypomethylation in interspersed repetitive sequences

21 January 2018

1 reference

Expression of human endogenous retrovirus K is stimulated by ultraviolet radiation in melanoma.

21 January 2018

1 reference

Bone morphogenetic proteins and retinoic acid induce human endogenous retrovirus HERV-K expression in NT2D1 human embryonal carcinoma cells.

21 January 2018

1 reference

Smoking Increases Transcription of Human Endogenous Retroviruses in a Newly Established in Vitro Cell Model and in Normal Urothelium

21 January 2018

1 reference

Epstein-Barr virus latent membrane protein LMP-2A is sufficient for transactivation of the human endogenous retrovirus HERV-K18 superantigen

21 January 2018

1 reference

HERV-K-specific T cells eliminate diverse HIV-1/2 and SIV primary isolates.

21 January 2018

1 reference

Expression of human endogenous retrovirus type K (HML-2) is activated by the Tat protein of HIV-1.

21 January 2018

1 reference

Activation of the long terminal repeat of human endogenous retrovirus K by melanoma-specific transcription factor MITF-M.

21 January 2018

1 reference

Expression of the human endogenous retrovirus (HERV) group HML-2/HERV-K does not depend on canonical promoter elements but is regulated by transcription factors Sp1 and Sp3.

21 January 2018

1 reference

Evidence that HERV-K is the endogenous retrovirus sequence that codes for the human teratocarcinoma-derived retrovirus HTDV.

21 January 2018

1 reference

Identification of an infectious progenitor for the multiple-copy HERV-K human endogenous retroelements

21 January 2018

1 reference

Reconstitution of an infectious human endogenous retrovirus

21 January 2018

1 reference

Endogenous retrovirus-K promoter: a landing strip for inflammatory transcription factors?

21 January 2018

1 reference

Physical and functional interactions of human endogenous retrovirus proteins Np9 and rec with the promyelocytic leukemia zinc finger protein

21 January 2018

1 reference

The viral oncogene Np9 acts as a critical molecular switch for co-activating β-catenin, ERK, Akt and Notch1 and promoting the growth of human leukemia stem/progenitor cells

21 January 2018

1 reference

The Rec protein of HERV-K(HML-2) upregulates androgen receptor activity by binding to the human small glutamine-rich tetratricopeptide repeat protein (hSGT).

21 January 2018

1 reference

Human endogenous retrovirus HERV-K113 is capable of producing intact viral particles

21 January 2018

1 reference

Human endogenous retrovirus HERV-K(HML-2) encodes a stable signal peptide with biological properties distinct from Rec

21 January 2018

1 reference

Human endogenous retrovirus rec interferes with germ cell development in mice and may cause carcinoma in situ, the predecessor lesion of germ cell tumors

21 January 2018

1 reference

The multifaceted role of Notch in cancer

21 January 2018

1 reference

21 January 2018

Inflammation and cancer

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Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity

21 January 2018

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The search for infectious causes of human cancers: where and why.

21 January 2018

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The transmembrane protein of the human endogenous retrovirus--K (HERV-K) modulates cytokine release and gene expression

21 January 2018

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The yin and yang of nitric oxide in cancer progression.

21 January 2018

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Nitric oxide-mediated activity in anti-cancer photodynamic therapy.

21 January 2018

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Candidate pathways linking inducible nitric oxide synthase to a basal-like transcription pattern and tumor progression in human breast cancer.

21 January 2018

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Increased NOS2 predicts poor survival in estrogen receptor-negative breast cancer patients

21 January 2018

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S-nitrosylation of EGFR and Src activates an oncogenic signaling network in human basal-like breast cancer

21 January 2018

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The roles of tumor-derived exosomes in cancer pathogenesis

21 January 2018

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Exosomes as biomarker treasure chests for prostate cancer

21 January 2018

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Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences

21 January 2018

1 reference

The Trojan exosome hypothesis

21 January 2018

1 reference

Effective treatment of metastatic forms of Epstein-Barr virus-associated nasopharyngeal carcinoma with a novel adenovirus-based adoptive immunotherapy

21 January 2018

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Improving T cell therapy for cancer

21 January 2018

1 reference

Inverse association between melanoma and previous vaccinations against tuberculosis and smallpox: results of the FEBIM study

21 January 2018

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Impact of vaccinations and infectious diseases on the risk of melanoma--evaluation of an EORTC case-control study

21 January 2018

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Does yellow fever 17D vaccine protect against melanoma?

21 January 2018

1 reference

The yellow fever 17D vaccine and risk of malignant melanoma in the United States military

21 January 2018

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Protection against melanoma by vaccination with Bacille Calmette-Guerin (BCG) and/or vaccinia: an epidemiology-based hypothesis on the nature of a melanoma risk factor and its immunological control

21 January 2018

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Melanoma, Darwinian medicine and the inner world

21 January 2018

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Human endogenous retroviruses and cancer prevention: evidence and prospects

21 January 2018

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Viruses and human cancer: from detection to causality

21 January 2018

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Potent antibody therapeutics by design

21 January 2018

1 reference

Vaccination directed against the human endogenous retrovirus-K envelope protein inhibits tumor growth in a murine model system

21 January 2018

1 reference

Human endogenous retrovirus K (HML-2) RNA and protein expression is a marker for human embryonic and induced pluripotent stem cells.

21 January 2018

1 reference

Molecular mechanisms of HBV-associated hepatocarcinogenesis.

21 January 2018

1 reference

Jaagsiekte sheep retrovirus biology and oncogenesis

21 January 2018

1 reference

Nucleotide sequence of human endogenous retrovirus genome related to the mouse mammary tumor virus genome

21 January 2018

1 reference

12 December 2020

Methylation of endogenous human retroelements in health and disease.

1 reference

12 December 2020

Brief communication: C-type particles in normal human placentas

1 reference

12 December 2020

Serological response to human endogenous retrovirus K in melanoma patients correlates with survival probability

1 reference

12 December 2020

Expression of the human endogenous retrovirus HTDV/HERV-K is enhanced by cellular transcription factor YY1

1 reference

12 December 2020

A human endogenous retroviral sequence encoding an antigen recognized on melanoma by cytolytic T lymphocytes.

1 reference

12 December 2020

The activation of human endogenous retrovirus K (HERV-K) is implicated in melanoma cell malignant transformation

1 reference

12 December 2020

Differential expression of human endogenous retrovirus K transcripts in primary human melanocytes and melanoma cell lines after UV irradiation

1 reference

12 December 2020

Human endogenous retroviruses: nature, occurrence, and clinical implications in human disease

1 reference

12 December 2020

Exosomes: composition, biogenesis and function

1 reference

12 December 2020

The Environment and Disease: Association or Causation?

1 reference

12 December 2020

Retrovirus-like particles released from the human breast cancer cell line T47-D display type B- and C-related endogenous retroviral sequences

1 reference

12 December 2020

Expression of the human endogenous retrovirus-K transmembrane envelope, Rec and Np9 proteins in melanomas and melanoma cell lines

1 reference

12 December 2020

Causation and disease: the Henle-Koch postulates revisited

1 reference

12 December 2020

Stimulation of expression of the human endogenous retrovirus genome by female steroid hormones in human breast cancer cell line T47D.

1 reference

12 December 2020

Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas

1 reference

12 December 2020

Adoptive immunotherapy for EBV-associated malignancies

1 reference

12 December 2020

Insertional polymorphisms of full-length endogenous retroviruses in humans

1 reference

12 December 2020

Expression of HERV-K proviruses in human leukocytes.

1 reference

12 December 2020

An endogenous retrovirus derived from human melanoma cells.

1 reference

12 December 2020

Expression of human endogenous retrovirus k envelope transcripts in human breast cancer

1 reference

12 December 2020

Identification of the HERV-K gag antigen in prostate cancer by SEREX using autologous patient serum and its immunogenicity

1 reference

12 December 2020

IDDM patients neither show humoral reactivities against endogenous retroviral envelope protein nor do they differ in retroviral mRNA expression from healthy relatives or normal individuals

1 reference

12 December 2020

A novel gene from the human endogenous retrovirus K expressed in transformed cells

1 reference

12 December 2020

Human endogenous retrovirus protein Rec interacts with the testicular zinc-finger protein and androgen receptor

1 reference

12 December 2020

Elevated HERV-K mRNA expression in PBMC is associated with a prostate cancer diagnosis particularly in older men and smokers

1 reference

12 December 2020

Identifiers

DOI

10.1002/IJC.29003

2 references

Consolidated OpenCitations Corpus – April 2017

5065056

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890612%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

5065056

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890612%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

PubMed publication ID

24890612

2 references

Consolidated OpenCitations Corpus – April 2017

5065056

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890612%20AND%20SRC:MED&resulttype=core&format=json