(Q27010700)

21 June 2017

title

Multiscale models of cell signaling (English)

1 reference

21 June 2017

2

Kevin A Janes

Kevin A

Janes

1 reference

21 June 2017

Sameer S Bajikar

1

Sameer S

Bajikar

1 reference

21 June 2017

language of work or name

1 reference

3 April 2012

1 reference

Annals of Biomedical Engineering

21 June 2017

published in

1 reference

21 June 2017

volume

40

1 reference

21 June 2017

issue

11

1 reference

21 June 2017

page(s)

2319-2327

1 reference

Systematic and quantitative assessment of the ubiquitin-modified proteome

21 June 2017

cites work

1 reference

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Normal morphogenesis of epithelial tissues and progression of epithelial tumors

21 March 2017

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Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum

21 March 2017

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A fourth IkappaB protein within the NF-kappaB signaling module

21 March 2017

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A comprehensive pathway map of epidermal growth factor receptor signaling

21 March 2017

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Modeling T cell antigen discrimination based on feedback control of digital ERK responses

21 March 2017

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STRING: known and predicted protein-protein associations, integrated and transferred across organisms

21 March 2017

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The Roles of APC and Axin Derived from Experimental and Theoretical Analysis of the Wnt Pathway

21 March 2017

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21 March 2017

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RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

21 March 2017

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Oncogenic kinase signalling

21 March 2017

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Modeling a snap-action, variable-delay switch controlling extrinsic cell death

21 March 2017

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Modeling HER2 effects on cell behavior from mass spectrometry phosphotyrosine data

21 March 2017

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Emergent properties of networks of biological signaling pathways

21 March 2017

1 reference

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RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

21 March 2017

1 reference

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Causal protein-signaling networks derived from multiparameter single-cell data

7 April 2017

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The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation

7 April 2017

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A new approach to decoding life: systems biology

7 April 2017

1 reference

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Using Bayesian networks to analyze expression data

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Robustness in bacterial chemotaxis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Use of an oriented peptide library to determine the optimal substrates of protein kinases

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Systematic Discovery of In Vivo Phosphorylation Networks

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Global identification of modular cullin-RING ligase substrates

9 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Robustness portraits of diverse biological networks conserved despite order-of-magnitude parameter uncertainty

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Ensuring congruency in multiscale modeling: towards linking agent based and continuum biomechanical models of arterial adaptation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Self-organizing and stochastic behaviors during the regeneration of hair stem cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Will the ubiquitin system furnish as many drug targets as protein kinases?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Pairwise network mechanisms in the host signaling response to coxsackievirus B3 infection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Ligand-specific c-Fos expression emerges from the spatiotemporal control of ErbB network dynamics

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Multiscale modeling of diffusion in the early Drosophila embryo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Identifying single-cell molecular programs by stochastic profiling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Protein dynamics in drug combinations: a linear superposition of individual-drug responses

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

The incoherent feedforward loop can provide fold-change detection in gene regulation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Unlimited multistability in multisite phosphorylation systems

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Deciphering signaling outcomes from a system of complex networks.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Systems-level interactions between insulin-EGF networks amplify mitogenic signaling.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Fuzzy logic analysis of kinase pathway crosstalk in TNF/EGF/insulin-induced signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Elongation, proliferation & migration differentiate endothelial cell phenotypes and determine capillary sprouting

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Linear combinations of docking affinities explain quantitative differences in RTK signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Cytokine-induced signaling networks prioritize dynamic range over signal strength

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Phosphoproteomics: unraveling the signaling web.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Capturing cell-fate decisions from the molecular signatures of a receptor-dependent signaling response

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Common effector processing mediates cell-specific responses to stimuli

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Quantitative network signal combinations downstream of TCR activation can predict IL-2 production response

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Data-driven modelling of signal-transduction networks

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Collecting and organizing systematic sets of protein data

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Isoelectric focusing technology quantifies protein signaling in 25 cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

The response of human epithelial cells to TNF involves an inducible autocrine cascade

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

A biological approach to computational models of proteomic networks

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Stimulus specificity of gene expression programs determined by temporal control of IKK activity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

A rapid method for determining protein kinase phosphorylation specificity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Automatic generation of cellular reaction networks with Moleculizer 1.0.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Mathematical modeling reveals threshold mechanism in CD95-induced apoptosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

BioNetGen: software for rule-based modeling of signal transduction based on the interactions of molecular domains

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Multicellular simulation predicts microvascular patterning and in silico tissue assembly

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Gene expression and the myth of the average cell

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Overview of the Alliance for Cellular Signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

The ins and outs of signalling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Probing cellular protein complexes using single-molecule pull-down

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Pairwise agonist scanning predicts cellular signaling responses to combinatorial stimuli

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Cytokine-associated drug toxicity in human hepatocytes is associated with signaling network dysregulation

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Dynamics and variability of ERK2 response to EGF in individual living cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Kinetic analysis of platelet-derived growth factor receptor/phosphoinositide 3-kinase/Akt signaling in fibroblasts

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment.

31 May 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10439-012-0560-1

Combinatorial complexity and dynamical restriction of network flows in signal transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10439-012-0560-1

Autophosphorylation of FGFR1 kinase is mediated by a sequential and precisely ordered reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10439-012-0560-1

Paring down signaling complexity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10439-012-0560-1

Do morphogen gradients arise by diffusion?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10439-012-0560-1

Adenoviral vector saturates Akt pro-survival signaling and blocks insulin-mediated rescue of tumor necrosis-factor-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10439-012-0560-1

Modeling beta-adrenergic control of cardiac myocyte contractility in silico

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10439-012-0560-1

Quantification of Short Term Signaling by the Epidermal Growth Factor Receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10439-012-0560-1

The complexity of cell signaling and the need for a new mechanics

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

'On-the-fly' or 'generate-first' modeling?

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436998

Linking a genetic defect to its cellular phenotype in a cardiac arrhythmia

28 November 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10439-012-0560-1

A compendium of signals and responses triggered by prodeath and prosurvival cytokines

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22476894

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22476894

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A global analysis of cross-talk in a mammalian cellular signalling network

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22476894

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S10439-012-0560-1

1 reference

Dimensions Publication ID

21 June 2017

0 references

1 reference

1 reference