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Control of cell identity in pancreas development and regeneration
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PubMed
title
Control of cell identity in pancreas development and regeneration
(English)
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main subject
pancreas
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author name string
Ben Z. Stanger
series ordinal
1
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Crossref
Matthias Hebrok
series ordinal
2
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stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
June 2013
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stated in
PubMed
published in
Gastroenterology
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stated in
PubMed
volume
144
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stated in
PubMed
issue
6
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stated in
PubMed
page(s)
1170-9
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stated in
PubMed
cites work
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Mutations in PTF1A cause pancreatic and cerebellar agenesis
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Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence
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Pancreatic mesenchyme regulates epithelial organogenesis throughout development
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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
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21 March 2017
In vivo reprogramming of adult pancreatic exocrine cells to beta-cells
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21 March 2017
Hereditary pancreatitis and the risk of pancreatic cancer. International Hereditary Pancreatitis Study Group
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21 March 2017
Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas
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21 March 2017
Beta-catenin is essential for pancreatic acinar but not islet development
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PubMed Central
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21 March 2017
Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex
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PubMed Central
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21 March 2017
EMT and dissemination precede pancreatic tumor formation
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PubMed Central
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7 April 2017
CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans
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PubMed Central
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Epigenetics: a landscape takes shape
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PubMed Central
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7 April 2017
Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation
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PubMed Central
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7 April 2017
Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure
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PubMed Central
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28 September 2017
β-cell mass and turnover in humans: effects of obesity and aging
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PubMed Central
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28 September 2017
Cholangiocarcinomas can originate from hepatocytes in mice
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
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28 September 2017
β-catenin is selectively required for the expansion and regeneration of mature pancreatic acinar cells in mice
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PubMed Central
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28 September 2017
Reprogramming of pancreatic exocrine cells towards a beta (β) cell character using Pdx1, Ngn3 and MafA
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PubMed Central
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28 September 2017
Ongoing Notch signaling maintains phenotypic fidelity in the adult exocrine pancreas.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
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28 September 2017
Nkx2.2 repressor complex regulates islet β-cell specification and prevents β-to-α-cell reprogramming
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PubMed Central
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28 September 2017
Context-specific α- to-β-cell reprogramming by forced Pdx1 expression.
1 reference
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PubMed Central
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28 September 2017
Pancreatic β cell identity is maintained by DNA methylation-mediated repression of Arx.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
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28 September 2017
Suppression of Ptf1a activity induces acinar-to-endocrine conversion.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
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28 September 2017
How neural mediation of anticipatory and compensatory insulin release helps us tolerate food
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PubMed Central
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28 September 2017
KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma.
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PubMed Central
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28 September 2017
Primary cilia regulate Gli/Hedgehog activation in pancreas
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PubMed Central
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28 September 2017
Replacement of Rbpj with Rbpjl in the PTF1 complex controls the final maturation of pancreatic acinar cells
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PubMed Central
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28 September 2017
Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
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28 September 2017
Cellular plasticity within the pancreas--lessons learned from development
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
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28 September 2017
The comparative anatomy of islets
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
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28 September 2017
Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
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28 September 2017
Retinoic acid signaling organizes endodermal organ specification along the entire antero-posterior axis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
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28 September 2017
Adaptive beta-cell proliferation is severely restricted with advanced age.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
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28 September 2017
Age-dependent decline in beta-cell proliferation restricts the capacity of beta-cell regeneration in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
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28 September 2017
Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
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28 September 2017
Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 September 2017
Notch signaling is required for exocrine regeneration after acute pancreatitis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 September 2017
The origin of islet-like cells in Drosophila identifies parallels to the vertebrate endocrine axis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
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28 September 2017
Pancreas phylogeny and ontogeny in relation to a 'pancreatic stem cell'.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
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28 September 2017
Dynamics of embryonic pancreas development using real-time imaging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 September 2017
Embryonic endocrine pancreas and mature beta cells acquire alpha and PP cell phenotypes upon Arx misexpression.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
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28 September 2017
The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
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28 September 2017
Acute pancreatitis: animal models and recent advances in basic research
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 September 2017
Mutant neurogenin-3 in congenital malabsorptive diarrhea
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 September 2017
Hedgehog signaling in pancreas development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 September 2017
Molecular basis of transdifferentiation of pancreas to liver
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 September 2017
Glucose-dependent insulin release from genetically engineered K cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 September 2017
beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 September 2017
Notochord repression of endodermal Sonic hedgehog permits pancreas development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 September 2017
Expression of neuronal traits in pancreatic beta cells. Implication of neuron-restrictive silencing factor/repressor element silencing transcription factor, a neuron-restrictive silencer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 September 2017
Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
31 May 2018
Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
31 May 2018
Epithelial dynamics of pancreatic branching morphogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
31 May 2018
Dynamic signaling network for the specification of embryonic pancreas and liver progenitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
31 May 2018
Hedgehog signaling is required for effective regeneration of exocrine pancreas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
31 May 2018
Recovery from diabetes in mice by beta cell regeneration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
31 May 2018
Generation of functional insulin-producing cells in the gut by Foxo1 ablation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 November 2018
Duct cells contribute to regeneration of endocrine and acinar cells following pancreatic damage in adult mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 November 2018
Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 November 2018
Neurogenin3 is sufficient for transdetermination of hepatic progenitor cells into neo-islets in vivo but not transdifferentiation of hepatocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 November 2018
Regulated beta-cell regeneration in the adult mouse pancreas.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 November 2018
A multipotent progenitor domain guides pancreatic organogenesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 November 2018
Stabilization of beta-catenin impacts pancreas growth.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 November 2018
Retinoids signal directly to zebrafish endoderm to specify insulin-expressing beta-cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 November 2018
Recapitulation of elements of embryonic development in adult mouse pancreatic regeneration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 November 2018
Notch inhibits Ptf1 function and acinar cell differentiation in developing mouse and zebrafish pancreas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 November 2018
Endothelial cell interactions initiate dorsal pancreas development by selectively inducing the transcription factor Ptf1a.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 November 2018
Signals from lateral plate mesoderm instruct endoderm toward a pancreatic fate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 November 2018
Novel SOX9 expression during human pancreas development correlates to abnormalities in Campomelic dysplasia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 November 2018
Induction of pancreatic differentiation by signals from blood vessels.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 November 2018
Early mouse endoderm is patterned by soluble factors from adjacent germ layers.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 November 2018
Notochord to endoderm signaling is required for pancreas development.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639438
retrieved
28 November 2018
Developmental biology of the pancreas
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23622126
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Dissociation and reassembly of adherens junctions during experimental acute pancreatitis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23622126
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Notch/Rbp-j signaling prevents premature endocrine and ductal cell differentiation in the pancreas
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23622126
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Chronic Pancreatitis Is Essential for Induction of Pancreatic Ductal Adenocarcinoma by K-Ras Oncogenes in Adult Mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23622126
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mutant neurogenin-3 in congenital malabsorptive diarrhea
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23622126
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1053/J.GASTRO.2013.01.074
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1003612
OpenCitations bibliographic resource ID
1003612
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1003612
PMC publication ID
3639438
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1003612
PubMed publication ID
23622126
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1003612
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