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In vivo reprogramming of adult pancreatic exocrine cells to beta-cells
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scholarly article
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title
In vivo reprogramming of adult pancreatic exocrine cells to beta-cells
(English)
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author
Douglas A. Melton
series ordinal
5
object named as
Douglas A Melton
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author name string
Qiao Zhou
series ordinal
1
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Juliana Brown
series ordinal
2
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Andrew Kanarek
series ordinal
3
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Jayaraj Rajagopal
series ordinal
4
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language of work or name
English
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publication date
2 October 2008
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published in
Nature
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volume
455
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issue
7213
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page(s)
627-32
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cites work
Stem Cells
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Nuclear reprogramming and pluripotency
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Metaplasia and transdifferentiation: from pure biology to the clinic
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Crossref
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Plasticity and reprogramming of differentiated cells in amphibian regeneration
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Crossref
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From nuclear transfer to nuclear reprogramming: the reversal of cell differentiation
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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
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Crossref
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Induction of pluripotent stem cells from adult human fibroblasts by defined factors
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Induced pluripotent stem cell lines derived from human somatic cells
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Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells
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Molecular basis of transdifferentiation of pancreas to liver
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Stepwise reprogramming of B cells into macrophages
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Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors
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fgf20 is essential for initiating zebrafish fin regeneration
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Cell differentiation and cell fate during urodele tail and limb regeneration
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A multipotent progenitor domain guides pancreatic organogenesis.
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Genes, Signals, and Lineages in Pancreas Development
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Gene regulatory factors in pancreatic development
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inferred from DOI database lookup
In vitro generation of insulin-producing beta cells from adult exocrine pancreatic cells
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Crossref
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7 January 2021
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inferred from DOI database lookup
Lineage tracing and characterization of insulin-secreting cells generated from adult pancreatic acinar cells
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7 January 2021
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inferred from DOI database lookup
Comparison of adenoviral and adeno-associated viral vectors for pancreatic gene delivery in vivo
1 reference
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Adenovirus transduction is required for the correction of diabetes using Pdx-1 or Neurogenin-3 in the liver
1 reference
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Role of VEGF-A in vascularization of pancreatic islets
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EphA-Ephrin-A-mediated beta cell communication regulates insulin secretion from pancreatic islets
1 reference
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Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia
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7 January 2021
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PDX-1/VP16 fusion protein, together with NeuroD or Ngn3, markedly induces insulin gene transcription and ameliorates glucose tolerance
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Ectopically expressed PDX-1 in liver initiates endocrine and exocrine pancreas differentiation but causes dysmorphogenesis.
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Crossref
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Pancreatic acinar-to-beta cell transdifferentiation in vitro
1 reference
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Crossref
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7 January 2021
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Generation of insulin-secreting cells from pancreatic acinar cells of animal models of type 1 diabetes.
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Crossref
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Cell-replacement therapy for diabetes: Generating functional insulin-producing tissue from adult human liver cells.
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Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3
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Crossref
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Proendocrine genes coordinate the pancreatic islet differentiation program in vitro
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7 January 2021
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Endocrine precursor cells from mouse islets are not generated by epithelial-to-mesenchymal transition of mature beta cells
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Epithelial-to-Mesenchymal Transition Generates Proliferative Human Islet Precursor Cells
1 reference
stated in
Crossref
reference URL
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inferred from DOI database lookup
Gene activation in somatic nuclei after injection into amphibian oocytes / E. M. De Robertis, J. B. Gurdon. - (1977)
1 reference
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Crossref
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7 January 2021
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Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation
1 reference
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Crossref
reference URL
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7 January 2021
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Identifiers
DOI
10.1038/NATURE07314
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
131777
ADS bibcode
2008Natur.455..627Z
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Dimensions Publication ID
1005774015
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OpenCitations bibliographic resource ID
131777
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
131777
PubMed ID
18754011
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
131777
ResearchGate publication ID
23220434
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