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The pathophysiology of IgA nephropathy
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Europe PubMed Central
title
The pathophysiology of IgA nephropathy
(English)
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main subject
pathophysiology
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based on heuristic
inferred from title
kidney disease
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inferred from title
author
Robert Wyatt
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7
object named as
R. J. Wyatt
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author name string
H. Suzuki
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K. Kiryluk
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J. Novak
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Z. Moldoveanu
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A. B. Herr
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M. B. Renfrow
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F. Scolari
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J. Mestecky
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A. G. Gharavi
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B. A. Julian
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language of work or name
English
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PubMed
publication date
October 2011
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published in
Journal of the American Society of Nephrology
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PubMed
volume
22
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PubMed
issue
10
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PubMed
page(s)
1795-803
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PubMed
cites work
Common variants at five new loci associated with early-onset inflammatory bowel disease
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Identification and characterization of CMP-NeuAc:GalNAc-IgA1 alpha2,6-sialyltransferase in IgA1-producing cells
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PubMed Central
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21 March 2017
Initiation of O-glycan synthesis in IgA1 hinge region is determined by a single enzyme, UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2
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21 March 2017
Cloning and expression of human core 1 beta1,3-galactosyltransferase
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21 March 2017
Insights into IgA-mediated immune responses from the crystal structures of human FcalphaRI and its complex with IgA1-Fc
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The Fab and Fc fragments of IgA1 exhibit a different arrangement from that in IgG: a study by X-ray and neutron solution scattering and homology modelling
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An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD)
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21 March 2017
Genome-wide association study identifies susceptibility loci for IgA nephropathy
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PubMed Central
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28 September 2017
The pathogenesis of IgA nephropathy
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PubMed Central
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28 September 2017
Clustered O-glycans of IgA1: defining macro- and microheterogeneity by use of electron capture/transfer dissociation.
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28 September 2017
HLA has strongest association with IgA nephropathy in genome-wide analysis
1 reference
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PubMed Central
reference URL
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28 September 2017
Genetic studies of IgA nephropathy: past, present, and future.
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PubMed Central
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28 September 2017
Comparison of methods for profiling O-glycosylation: Human Proteome Organisation Human Disease Glycomics/Proteome Initiative multi-institutional study of IgA1
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PubMed Central
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28 September 2017
Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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28 September 2017
Analysis of IgA1 N-glycosylation and its contribution to FcalphaRI binding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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28 September 2017
Toll-like receptor 9 affects severity of IgA nephropathy
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PubMed Central
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28 September 2017
Balancing selection and heterogeneity across the classical human leukocyte antigen loci: a meta-analytic review of 497 population studies
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28 September 2017
Aberrant IgA1 glycosylation is inherited in familial and sporadic IgA nephropathy
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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28 September 2017
Role of aberrant glycosylation of IgA1 molecules in the pathogenesis of IgA nephropathy
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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28 September 2017
IgA1-secreting cell lines from patients with IgA nephropathy produce aberrantly glycosylated IgA1
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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28 September 2017
Analysis of O-glycan heterogeneity in IgA1 myeloma proteins by Fourier transform ion cyclotron resonance mass spectrometry: implications for IgA nephropathy.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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28 September 2017
IgA nephropathy and Henoch-Schoenlein purpura nephritis: aberrant glycosylation of IgA1, formation of IgA1-containing immune complexes, and activation of mesangial cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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28 September 2017
Reactivities of N-acetylgalactosamine-specific lectins with human IgA1 proteins
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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28 September 2017
O-glycosylation of serum IgA1 antibodies against mucosal and systemic antigens in IgA nephropathy.
1 reference
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PubMed Central
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28 September 2017
Determination of aberrant O-glycosylation in the IgA1 hinge region by electron capture dissociation fourier transform-ion cyclotron resonance mass spectrometry.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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28 September 2017
IgA nephropathy: an update
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PubMed Central
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28 September 2017
Incidence of latent mesangial IgA deposition in renal allograft donors in Japan
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PubMed Central
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28 September 2017
Interactions of human mesangial cells with IgA and IgA-containing immune complexes
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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28 September 2017
Identification of the transferrin receptor as a novel immunoglobulin (Ig)A1 receptor and its enhanced expression on mesangial cells in IgA nephropathy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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28 September 2017
Absence of CD89, polymeric immunoglobulin receptor, and asialoglycoprotein receptor on human mesangial cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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28 September 2017
Circulating immune complexes in IgA nephropathy consist of IgA1 with galactose-deficient hinge region and antiglycan antibodies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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28 September 2017
Immunoglobulin and complement deposition in glomeruli of 756 subjects who had committed suicide or met with a violent death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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28 September 2017
IgA immune complexes in Henoch-Schönlein purpura
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
retrieved
28 September 2017
Recognition of galactose-deficient O-glycans in the hinge region of IgA1 by N-acetylgalactosamine-specific snail lectins: a comparative binding study
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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31 May 2018
[Intercapillary deposits of IgA-IgG]
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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31 May 2018
Immunostaining findings in IgA nephropathy: correlation with histology and clinical outcome in the Oxford classification patient cohort
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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28 November 2018
Quantitation of saccharide compositions of O-glycans by mass spectrometry of glycopeptides and its application to rheumatoid arthritis
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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28 November 2018
Evaluation of the specific structures of IgA1 hinge glycopeptide in 30 IgA nephropathy patients by mass spectrometry
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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28 November 2018
IgA nephropathy at two score and one.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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28 November 2018
Podocyte injury induced by mesangial-derived cytokines in IgA nephropathy
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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28 November 2018
Electrophoretic methods for analysis of urinary polypeptides in IgA-associated renal diseases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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28 November 2018
Protein glycosylation: chaperone mutation in Tn syndrome
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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28 November 2018
Engagement of Transferrin Receptor by Polymeric IgA1: Evidence for a Positive Feedback Loop Involving Increased Receptor Expression and Mesangial Cell Proliferation in IgA Nephropathy
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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28 November 2018
Glycosylation and size of IgA1 are essential for interaction with mesangial transferrin receptor in IgA nephropathy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892742
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28 November 2018
IgA-containing circulating immune complexes in dermatitis herpetiformis, Henoch-Schönlein purpura, systemic lupus erythematosus and other diseases
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21949093
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Disappearance of glomerular mesangial IgA deposits after renal allograft transplantation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21949093
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The mesangium and glomerulonephritis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21949093
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Frequency of mesangial IgA deposits in a non-selected autopsy series
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21949093
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Glycosylation of IgA is required for optimal activation of the alternative complement pathway by immune complexes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21949093
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
IgA1-containing immune complexes in IgA nephropathy differentially affect proliferation of mesangial cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21949093
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
IgA-containing immune complexes in the urine of IgA nephropathy patients
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21949093
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Patients with IgA nephropathy have increased serum galactose-deficient IgA1 levels
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21949093
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Activation of podocytes by mesangial-derived TNF-alpha: glomerulo-podocytic communication in IgA nephropathy
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21949093
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Serum under-galactosylated IgA1 is increased in Japanese patients with IgA nephropathy
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21949093
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1681/ASN.2011050464
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2353657
Fatcat ID
release_mmrmwrojbnb73b5x4xbmubwjqi
0 references
OpenCitations bibliographic resource ID
2353657
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2353657
PMC publication ID
3892742
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2353657
PubMed publication ID
21949093
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2353657
ResearchGate publication ID
51665141
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