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Therapeutic approaches to non-alcoholic fatty liver disease: past achievements and future challenges
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PubMed
title
Therapeutic approaches to non-alcoholic fatty liver disease: past achievements and future challenges
(English)
0 references
main subject
metabolic dysfunction–associated steatotic liver disease
1 reference
based on heuristic
inferred from title
non-alcoholic fatty liver
1 reference
based on heuristic
inferred from title
liver disease
1 reference
based on heuristic
inferred from title
author name string
Xiao J
series ordinal
1
1 reference
stated in
PubMed
Guo R
series ordinal
2
1 reference
stated in
PubMed
Fung ML
series ordinal
3
1 reference
stated in
PubMed
Liong EC
series ordinal
4
1 reference
stated in
PubMed
Tipoe GL
series ordinal
5
1 reference
stated in
PubMed
language of work or name
English
1 reference
stated in
PubMed
publication date
April 2013
1 reference
stated in
PubMed
published in
Hepatobiliary & Pancreatic Diseases International
1 reference
stated in
PubMed
volume
12
1 reference
stated in
PubMed
issue
2
1 reference
stated in
PubMed
page(s)
125-35
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stated in
PubMed
cites work
Prevalence of and risk factors for nonalcoholic fatty liver disease: the Dionysos nutrition and liver study.
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Epidemiology of non-alcoholic fatty liver disease in China.
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Non-alcoholic fatty liver disease as a risk factor for hepatocellular carcinoma: mechanisms and implications
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Spectrum of NAFLD and diagnostic implications of the proposed new normal range for serum ALT in obese women
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Nonalcoholic fatty liver disease: multimodal treatment options for a pathogenetically multiple-hit disease
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Review article: is non-alcoholic fatty liver disease a spectrum, or are steatosis and non-alcoholic steatohepatitis distinct conditions?
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Non-alcoholic fatty liver disease and metabolic syndrome in adolescents: pathogenetic role of genetic background and intrauterine environment
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NAFLD in the absence of metabolic syndrome: different epidemiology, pathogenetic mechanisms, risk factors for disease progression?
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Dyslipidemia in patients with nonalcoholic fatty liver disease.
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Non-alcoholic fatty liver disease: a new and important cardiovascular risk factor?
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Non-alcoholic fatty liver disease in type 2 diabetes: pathogenesis and treatment options
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Risk of chronic kidney disease in patients with non-alcoholic fatty liver disease: is there a link?
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Nonalcoholic fatty liver disease is related to nonalcoholic fatty pancreas disease
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Mechanisms of disease progression in nonalcoholic fatty liver disease
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Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: The central role of nontriglyceride fatty acid metabolites
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Molecular mechanisms involved in NAFLD progression
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The next generation of obesity research: no time to waste
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Bariatric surgery worldwide 2003.
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Obesity and weight management in the elderly.
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Obesity, weight loss and prognosis in type 2 diabetes
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Crossref
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A comparison of body mass index, waist-hip ratio and waist circumference as predictors of all-cause mortality among the elderly: the Rotterdam study
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Body weight and weight change and their health implications for the elderly.
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Sucrose compared with artificial sweeteners: different effects on ad libitum food intake and body weight after 10 wk of supplementation in overweight subjects
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7 January 2021
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Dietary composition during weight-loss maintenance
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Crossref
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Effect of weight reduction on hepatic abnormalities in overweight patients
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Reversal of nonalcoholic hepatic steatosis, hepatic insulin resistance, and hyperglycemia by moderate weight reduction in patients with type 2 diabetes
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Lifestyle interventions for the treatment of non-alcoholic fatty liver disease in adults: a systematic review.
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Healthy-lifestyle behaviors associated with overweight and obesity in US rural children
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Benefits of lifestyle modification in NAFLD.
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Exercise training increases lipid metabolism gene expression in human skeletal muscle
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Regular exercise is associated with a reduction in the risk of NAFLD and decreased liver enzymes in individuals with NAFLD independent of obesity in Korean adults
1 reference
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Crossref
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Effect of exercise and dietary modification on serum aminotransferase levels in patients with nonalcoholic steatohepatitis
1 reference
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Crossref
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7 January 2021
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Independent effects of physical activity in patients with nonalcoholic fatty liver disease
1 reference
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Crossref
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7 January 2021
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Exercise and the liver: implications for therapy in fatty liver disorders
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Exercise protects against high-fat diet-induced hypothalamic inflammation
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Exercise training attenuates hepatic inflammation, fibrosis and macrophage infiltration during diet induced-obesity in mice.
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Randomized controlled trial testing the effects of weight loss on nonalcoholic steatohepatitis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Physiologic action of glucagon on liver glucose metabolism
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
RETRACTED: Hepatic glucagon action is essential for exercise-induced reversal of mouse fatty liver
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cytokines and NASH: a pilot study of the effects of lifestyle modification and vitamin E.
1 reference
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Crossref
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7 January 2021
based on heuristic
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Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality
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7 January 2021
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7 January 2021
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7 January 2021
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Resveratrol improves non-alcoholic fatty liver disease by activating AMP-activated protein kinase
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Resveratrol inhibits nonalcoholic fatty liver disease in rats
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol
1 reference
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Crossref
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7 January 2021
based on heuristic
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Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation.
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Green tea extract protects leptin-deficient, spontaneously obese mice from hepatic steatosis and injury
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7 January 2021
based on heuristic
inferred from DOI database lookup
The major green tea polyphenol, (-)-epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat-fed mice
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7 January 2021
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Epigallocatechin-3-gallate improves nonalcoholic steatohepatitis model mice expressing nuclear sterol regulatory element binding protein-1c in adipose tissue.
1 reference
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7 January 2021
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Green tea extract attenuates hepatic steatosis by decreasing adipose lipogenesis and enhancing hepatic antioxidant defenses in ob/ob mice
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cross sectional study of effects of drinking green tea on cardiovascular and liver diseases
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Green tea consumption and mortality due to cardiovascular disease, cancer, and all causes in Japan: the Ohsaki study.
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms for insulin resistance: common threads and missing links
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7 January 2021
based on heuristic
inferred from DOI database lookup
Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: Selected practical issues in their evaluation and management
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Journeys of the Circle: a culturally congruent life skills intervention for adolescent Indian drinking
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7 January 2021
based on heuristic
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Effects of rosiglitazone and metformin on liver fat content, hepatic insulin resistance, insulin clearance, and gene expression in adipose tissue in patients with type 2 diabetes
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Rosiglitazone for nonalcoholic steatohepatitis: one-year results of the randomized placebo-controlled Fatty Liver Improvement with Rosiglitazone Therapy (FLIRT) Trial
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes
1 reference
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Crossref
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7 January 2021
based on heuristic
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The role of metformin in the management of NAFLD
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Pioglitazone: side effect and safety profile
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7 January 2021
based on heuristic
inferred from DOI database lookup
Metabolic effects of metformin in non-insulin-dependent diabetes mellitus
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Crossref
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https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Overview of metformin: special focus on metformin extended release
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7 January 2021
based on heuristic
inferred from DOI database lookup
Metformin and insulin suppress hepatic gluconeogenesis through phosphorylation of CREB binding protein
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https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
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7 January 2021
based on heuristic
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Metformin in the treatment of patients with non-alcoholic steatohepatitis
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Metformin in the treatment of non-alcoholic steatohepatitis: a pilot open label trial
1 reference
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Crossref
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7 January 2021
based on heuristic
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Histopathology of pediatric nonalcoholic fatty liver disease.
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
NAFLD in children: a prospective clinical-pathological study and effect of lifestyle advice
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Clinical trial: pilot study of metformin for the treatment of non-alcoholic steatohepatitis.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Metformin versus dietary treatment in nonalcoholic hepatic steatosis: a randomized study
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Treating insulin resistance in hypertension with metformin reduces both blood pressure and metabolic risk factors
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Acute sympathoinhibitory actions of metformin in spontaneously hypertensive rats
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7 January 2021
based on heuristic
inferred from DOI database lookup
Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis of randomised trials
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Review article: the emerging interplay among the gastrointestinal tract, bile acids and incretins in the pathogenesis of diabetes and non-alcoholic fatty liver disease
1 reference
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https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
3-hydroxyl-3-methylglutaryl coenzyme A reductase inhibitor use in chronic liver disease: a therapeutic controversy
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7 January 2021
based on heuristic
inferred from DOI database lookup
Safety and efficacy of long-term statin treatment for cardiovascular events in patients with coronary heart disease and abnormal liver tests in the Greek Atorvastatin and Coronary Heart Disease Evaluation (GREACE) Study: a post-hoc analysis
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7 January 2021
based on heuristic
inferred from DOI database lookup
Statins in non-alcoholic fatty liver disease and chronically elevated liver enzymes: a histopathological follow-up study
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Atorvastatin and antioxidants for the treatment of nonalcoholic fatty liver disease: the St Francis Heart Study randomized clinical trial.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Efficacy of atorvastatin for the treatment of nonalcoholic steatohepatitis with dyslipidemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A pilot study using simvastatin in the treatment of nonalcoholic steatohepatitis: A randomized placebo-controlled trial.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hydrophilicity/lipophilicity: relevance for the pharmacology and clinical effects of HMG-CoA reductase inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cholesterol-lowering therapy for the treatment of nonalcoholic fatty liver disease: an update
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HMG-CoA reductase inhibitors for treatment of hypercholesterolemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Statins and hepatotoxicity: focus on patients with fatty liver
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Beneficial effects of rosuvastatin on insulin resistance, adiposity, inflammatory markers and non-alcoholic fatty liver disease in mice fed on a high-fat diet.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of fenofibrate and niacin on intrahepatic triglyceride content, very low-density lipoprotein kinetics, and insulin action in obese subjects with nonalcoholic fatty liver disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telmisartan attenuates progression of steatohepatitis in mice: role of hepatic macrophage infiltration and effects on adipose tissue
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Angiotensin-receptor blockers as therapy for mild-to-moderate hypertension-associated non-alcoholic steatohepatitis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Combination treatment of angiotensin II type I receptor blocker and new oral iron chelator attenuates progression of nonalcoholic steatohepatitis in rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ursodeoxycholic acid for treatment of nonalcoholic steatohepatitis: results of a randomized trial
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bile acids for non-alcoholic fatty liver disease and/or steatohepatitis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High-dose ursodeoxycholic acid therapy for nonalcoholic steatohepatitis: a double-blind, randomized, placebo-controlled trial
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A pilot trial of pentoxifylline in nonalcoholic steatohepatitis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pentoxifylline improves nonalcoholic steatohepatitis: a randomized placebo-controlled trial
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
L-carnitine supplementation to diet: a new tool in treatment of nonalcoholic steatohepatitis--a randomized and controlled clinical trial
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gut--liver axis: the impact of gut microbiota on non alcoholic fatty liver disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A phase 2, randomized, double-blind, placebo-controlled study of GS-9450 in subjects with nonalcoholic steatohepatitis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Metabolic syndrome and risk factors for non-alcoholic fatty liver disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Review article: fructose in non-alcoholic fatty liver disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic determinants of susceptibility and severity in nonalcoholic fatty liver disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
What should we recommend to our patients with NAFLD regarding alcohol use?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Second-hand smoke stimulates lipid accumulation in the liver by modulating AMPK and SREBP-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Smoking and severity of hepatic fibrosis in nonalcoholic fatty liver disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Weight reduction for non-alcoholic fatty liver disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1499-3872%2813%2960021-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1499-3872(13)60021-1
0 references
Fatcat ID
release_zcrs33olhjb3hhm5edbd2ed37i
0 references
PubMed publication ID
23558065
1 reference
stated in
PubMed
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