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Progress in structural studies of telomerase
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PubMed
title
Progress in structural studies of telomerase
(English)
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author
Juli Feigon
series ordinal
4
object named as
Juli Feigon
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stated in
Crossref
author name string
Edward J Miracco
series ordinal
1
1 reference
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Crossref
Jiansen Jiang
series ordinal
2
1 reference
stated in
Crossref
Darian D Cash
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3
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Crossref
language of work or name
English
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stated in
PubMed
publication date
February 2014
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stated in
PubMed
published in
Current Opinion in Structural Biology
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stated in
PubMed
volume
24
1 reference
stated in
PubMed
page(s)
115-24
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stated in
PubMed
cites work
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An enhanced H/ACA RNP assembly mechanism for human telomerase RNA
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21 March 2017
Specificity and stoichiometry of subunit interactions in the human telomerase holoenzyme assembled in vivo
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21 March 2017
Solution structure and dynamics of the wild-type pseudoknot of human telomerase RNA
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21 March 2017
Structure of the Tetrahymena thermophila telomerase RNA helix II template boundary element
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21 March 2017
A Motif in the Vertebrate Telomerase N-Terminal Linker of TERT Contributes to RNA Binding and Telomerase Activity and Processivity
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21 March 2017
Pyrimidine motif triple helix in the Kluyveromyces lactis telomerase RNA pseudoknot is essential for function in vivo
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21 March 2017
Structure and conformational change of a replication protein A heterotrimer bound to ssDNA
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21 March 2017
Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65
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21 March 2017
Structural basis for Tetrahymena telomerase processivity factor Teb1 binding to single-stranded telomeric-repeat DNA
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PubMed Central
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21 March 2017
Structure of the Shq1-Cbf5-Nop10-Gar1 complex and implications for H/ACA RNP biogenesis and dyskeratosis congenita
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21 March 2017
Reconstitution and structural analysis of the yeast box H/ACA RNA-guided pseudouridine synthase
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21 March 2017
The H/ACA RNP assembly factor SHQ1 functions as an RNA mimic
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21 March 2017
Structure of H/ACA RNP Protein Nhp2p Reveals Cis/Trans Isomerization of a Conserved Proline at the RNA and Nop10 Binding Interface
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21 March 2017
Structural basis for telomerase catalytic subunit TERT binding to RNA template and telomeric DNA
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PubMed Central
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21 March 2017
Structure of the Tribolium castaneum telomerase catalytic subunit TERT
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PubMed Central
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21 March 2017
Structure of the RNA-binding domain of telomerase: implications for RNA recognition and binding
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21 March 2017
Essential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interaction
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21 March 2017
Structure of active dimeric human telomerase
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21 March 2017
Structure and function of telomerase RNA
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PubMed Central
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21 March 2017
Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection
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PubMed Central
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21 March 2017
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
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PubMed Central
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21 March 2017
Triple-helix structure in telomerase RNA contributes to catalysis
1 reference
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PubMed Central
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21 March 2017
A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in Tetrahymena
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PubMed Central
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21 March 2017
The serial cultivation of human diploid cell strains
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7 April 2017
A box H/ACA small nucleolar RNA-like domain at the human telomerase RNA 3' end
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7 April 2017
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
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7 April 2017
RNA connectivity requirements between conserved elements in the core of the yeast telomerase RNP.
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28 September 2017
Avoiding the pitfalls of single particle cryo-electron microscopy: Einstein from noise
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28 September 2017
Understanding telomere diseases through analysis of patient-derived iPS cells
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28 September 2017
Tetrahymena telomerase holoenzyme assembly, activation, and inhibition by domains of the p50 central hub
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28 September 2017
Telomerase at the intersection of cancer and aging
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28 September 2017
Identification of purple sea urchin telomerase RNA using a next-generation sequencing based approach
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PubMed Central
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28 September 2017
Identification of telomerase RNAs from filamentous fungi reveals conservation with vertebrates and yeasts
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PubMed Central
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28 September 2017
xRRM: a new class of RRM found in the telomerase La family protein p65.
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28 September 2017
New models of Tetrahymena telomerase RNA from experimentally derived constraints and modeling
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28 September 2017
The common ancestral core of vertebrate and fungal telomerase RNAs.
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28 September 2017
Mechanism of the AAA+ ATPases pontin and reptin in the biogenesis of H/ACA RNPs
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28 September 2017
Specificity requirements for human telomere protein interaction with telomerase holoenzyme
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PubMed Central
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28 September 2017
Biogenesis of telomerase ribonucleoproteins
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PubMed Central
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28 September 2017
The C-terminal domain of Tetrahymena thermophila telomerase holoenzyme protein p65 induces multiple structural changes in telomerase RNA.
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PubMed Central
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28 September 2017
RNA-protein binding interface in the telomerase ribonucleoprotein
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28 September 2017
The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis
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28 September 2017
Is telomerase a viable target in cancer?
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28 September 2017
Human telomerase model shows the role of the TEN domain in advancing the double helix for the next polymerization step.
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28 September 2017
Functional importance of telomerase pseudoknot revealed by single-molecule analysis
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28 September 2017
Telomerase structure function.
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28 September 2017
Tetrahymena telomerase protein p65 induces conformational changes throughout telomerase RNA (TER) and rescues telomerase reverse transcriptase and TER assembly mutants
1 reference
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PubMed Central
reference URL
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28 September 2017
Multiple mechanisms for elongation processivity within the reconstituted tetrahymena telomerase holoenzyme
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PubMed Central
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28 September 2017
Box H/ACA small ribonucleoproteins
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
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28 September 2017
An RPA-related sequence-specific DNA-binding subunit of telomerase holoenzyme is required for elongation processivity and telomere maintenance
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PubMed Central
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28 September 2017
A single-molecule assay for telomerase structure-function analysis
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PubMed Central
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28 September 2017
The box H/ACA ribonucleoprotein complex: interplay of RNA and protein structures in post-transcriptional RNA modification
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PubMed Central
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28 September 2017
Structures of telomerase subunits provide functional insights
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
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28 September 2017
Unveiling substrate RNA binding to H/ACA RNPs: one side fits all.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
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28 September 2017
Pseudoknot structures with conserved base triples in telomerase RNAs of ciliates
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
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28 September 2017
H/ACA guide RNAs, proteins and complexes
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
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28 September 2017
Stepwise protein-mediated RNA folding directs assembly of telomerase ribonucleoprotein
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
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28 September 2017
Positive and negative regulation of Tetrahymena telomerase holoenzyme
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
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28 September 2017
A novel RNA binding domain in tetrahymena telomerase p65 initiates hierarchical assembly of telomerase holoenzyme
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
retrieved
28 September 2017
Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
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28 September 2017
Telomere length homeostasis requires that telomerase levels are limiting
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
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28 September 2017
Structure of the human telomerase RNA pseudoknot reveals conserved tertiary interactions essential for function
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
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28 September 2017
Two purified domains of telomerase reverse transcriptase reconstitute sequence-specific interactions with RNA.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
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28 September 2017
The structure of an enzyme-activating fragment of human telomerase RNA.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
retrieved
28 September 2017
A universal telomerase RNA core structure includes structured motifs required for binding the telomerase reverse transcriptase protein
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
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28 September 2017
Holoenzyme proteins required for the physiological assembly and activity of telomerase
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
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28 September 2017
Tetrahymena telomerase is active as a monomer
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
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28 September 2017
Telomerase recognizes its template by using an adjacent RNA motif
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
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28 September 2017
Telomerase RNA bound by protein motifs specific to telomerase reverse transcriptase
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
retrieved
28 September 2017
Studying the telomerase RNA in Tetrahymena
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
retrieved
28 September 2017
A new telomerase RNA element that is critical for telomere elongation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
retrieved
31 May 2018
Single-molecule FRET reveals the folding dynamics of the human telomerase RNA pseudoknot domain
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
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31 May 2018
A comprehensive analysis of the La-motif protein superfamily
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PubMed Central
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31 May 2018
A triple helix within a pseudoknot is a conserved and essential element of telomerase RNA.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
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31 May 2018
Structural study of elements of Tetrahymena telomerase RNA stem-loop IV domain important for function
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
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31 May 2018
Biological and biochemical functions of RNA in the tetrahymena telomerase holoenzyme
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
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31 May 2018
The architecture of Tetrahymena telomerase holoenzyme
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
retrieved
28 November 2018
Large telomerase RNA, telomere length heterogeneity and escape from senescence inCandida glabrata
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
retrieved
28 November 2018
Crystal structure of an H/ACA box ribonucleoprotein particle.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984607
retrieved
28 November 2018
Identifiers
DOI
10.1016/J.SBI.2014.01.008
0 references
Fatcat ID
release_z7vnk3wqsfehhdvmmjnpkhfxwm
0 references
PMC publication ID
3984607
1 reference
stated in
PubMed
PubMed publication ID
24508601
1 reference
stated in
PubMed
ResearchGate publication ID
260129680
0 references
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