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Protein methylation at the surface and buried deep: thinking outside the histone box
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title
Protein methylation at the surface and buried deep: thinking outside the histone box
(English)
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author name string
Steven G. Clarke
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1
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language of work or name
English
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PubMed
publication date
May 2013
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PubMed
published in
Trends in Biochemical Sciences
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PubMed
volume
38
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PubMed
issue
5
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PubMed
page(s)
243-52
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PubMed
cites work
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Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling
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G9a and Glp methylate lysine 373 in the tumor suppressor p53
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Structure of protein phosphatase methyltransferase 1 (PPM1), a leucine carboxyl methyltransferase involved in the regulation of protein phosphatase 2A activity
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The ribosomal l1 protuberance in yeast is methylated on a lysine residue catalyzed by a seven-beta-strand methyltransferase
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A novel 3-methylhistidine modification of yeast ribosomal protein Rpl3 is dependent upon the YIL110W methyltransferase
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The yeast translation release factors Mrf1p and Sup45p (eRF1) are methylated, respectively, by the methyltransferases Mtq1p and Mtq2p
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Cytochrome c methyltransferase, Ctm1p, of yeast
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Histone methylation: a dynamic mark in health, disease and inheritance
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Protein arginine methyltransferases and cancer
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Histone lysine methylation dynamics: establishment, regulation, and biological impact
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Protein arginine methylation in Saccharomyces cerevisiae.
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Identification and characterization of a highly conserved crenarchaeal protein lysine methyltransferase with broad substrate specificity
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EZH2 generates a methyl degron that is recognized by the DCAF1/DDB1/CUL4 E3 ubiquitin ligase complex
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Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B.
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Methylation by Set9 modulates FoxO3 stability and transcriptional activity.
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RB1 methylation by SMYD2 enhances cell cycle progression through an increase of RB1 phosphorylation
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Substrate specificity of mammalian N-terminal α-amino methyltransferase NRMT
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Evaluation of substrate and inhibitor binding to yeast and human isoprenylcysteine carboxyl methyltransferases (Icmts) using biotinylated benzophenone-containing photoaffinity probes.
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Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation.
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28 September 2017
Human protein arginine methyltransferase 7 (PRMT7) is a type III enzyme forming ω-NG-monomethylated arginine residues.
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28 September 2017
PRC2 directly methylates GATA4 and represses its transcriptional activity
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28 September 2017
Lysine methyltransferase G9a methylates the transcription factor MyoD and regulates skeletal muscle differentiation
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RNA polymerase II carboxyl-terminal domain phosphorylation regulates protein stability of the Set2 methyltransferase and histone H3 di- and trimethylation at lysine 36
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28 September 2017
A proteomic approach for the identification of novel lysine methyltransferase substrates
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28 September 2017
Chromatin signaling to kinetochores: transregulation of Dam1 methylation by histone H2B ubiquitination
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28 September 2017
Substrate and product specificities of SET domain methyltransferases
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28 September 2017
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Auto-methylation of the mouse DNA-(cytosine C5)-methyltransferase Dnmt3a at its active site cysteine residue.
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Uncovering the human methyltransferasome
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28 September 2017
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CXXC finger protein 1 restricts the Setd1A histone H3K4 methyltransferase complex to euchromatin
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28 September 2017
Protein lysine methyltransferase G9a acts on non-histone targets
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28 September 2017
Co- and post-translational modifications in Rubisco: unanswered questions
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The emerging field of dynamic lysine methylation of non-histone proteins.
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28 September 2017
The lysine 831 of vascular endothelial growth factor receptor 1 is a novel target of methylation by SMYD3.
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28 September 2017
Methylation of proteins involved in translation
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28 September 2017
Structural and evolutionary bioinformatics of the SPOUT superfamily of methyltransferases
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28 September 2017
Protein arginine methyltransferases: evolution and assessment of their pharmacological and therapeutic potential
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28 September 2017
Organellar proteomics reveals Golgi arginine dimethylation
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28 September 2017
Cloning and developmental expression of pea ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit N-methyltransferase
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28 September 2017
N-terminal methylation of proteins: structure, function and specificity
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28 September 2017
Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation
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Characterization of HIV Tat modifications using novel methyl-lysine-specific antibodies
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Post-translational processing of rat ribosomal proteins. Ubiquitous methylation of Lys22 within the zinc-finger motif of RL40 (carboxy-terminal extension protein 52) and tissue-specific methylation of Lys4 in RL29.
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31 May 2018
The SET8 H4K20 protein lysine methyltransferase has a long recognition sequence covering seven amino acid residues.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634909
retrieved
28 November 2018
Specificity Analysis-Based Identification of New Methylation Targets of the SET7/9 Protein Lysine Methyltransferase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634909
retrieved
28 November 2018
The epigenetic magic of histone lysine methylation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634909
retrieved
28 November 2018
The role of MeH73 in actin polymerization and ATP hydrolysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634909
retrieved
28 November 2018
Proteomic analyses of the SMYD family interactomes identify HSP90 as a novel target for SMYD2
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23490039
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Yeast ribosomal/cytochrome c SET domain methyltransferase subfamily: identification of Rpl23ab methylation sites and recognition motifs
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23490039
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.TIBS.2013.02.004
0 references
Fatcat ID
release_wgxvru3rrnhvxpaqsaobm6rlyi
0 references
PMCID
3634909
1 reference
stated in
PubMed
PubMed ID
23490039
1 reference
stated in
PubMed
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