(Q27025964)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350947%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

Small-molecule-induced Rho-inhibition: NSAIDs after spinal cord injury (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350947%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350947%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Thomas Liebscher

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350947%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Stefan Laufer

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350947%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Stephen M. Strittmatter

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350947%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Ulrich Dirnagl

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350947%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Jan Schwab

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350947%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

author name string

A Niedeggen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350947%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

B Brommer

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350947%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

G J Jungehulsing

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350947%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

language of work or name

1 reference

21 February 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350947%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

published in

Cell and Tissue Research

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350947%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

volume

349

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350947%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

issue

1

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350947%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

page(s)

119-132

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350947%20AND%20SRC:MED&resulttype=core&format=json

Myelin suppresses axon regeneration by PIR-B/SHP-mediated inhibition of Trk activity

23 January 2020

cites work

1 reference

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Pathological and protective roles of glia in chronic pain

21 March 2017

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Oral non-steroidal anti-inflammatory drug therapy for lung disease in cystic fibrosis

21 March 2017

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Glial inhibition of CNS axon regeneration

21 March 2017

1 reference

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Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system

21 March 2017

1 reference

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Structure and axon outgrowth inhibitor binding of the Nogo-66 receptor and related proteins

21 March 2017

1 reference

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Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration

21 March 2017

1 reference

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EphA4 blockers promote axonal regeneration and functional recovery following spinal cord injury in mice

21 March 2017

1 reference

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LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex

21 March 2017

1 reference

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P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury

21 March 2017

1 reference

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P75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp

21 March 2017

1 reference

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Myelin-associated glycoprotein as a functional ligand for the Nogo-66 receptor

21 March 2017

1 reference

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Nogo-66 receptor antagonist peptide promotes axonal regeneration

21 March 2017

1 reference

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Nogo in the injured spinal cord

21 March 2017

1 reference

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Neogenin mediates the action of repulsive guidance molecule

21 March 2017

1 reference

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Molecular basis of the interactions of the Nogo-66 receptor and its homolog NgR2 with myelin-associated glycoprotein: development of NgROMNI-Fc, a novel antagonist of CNS myelin inhibition

21 March 2017

1 reference

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A sensitive and reliable locomotor rating scale for open field testing in rats

21 March 2017

1 reference

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Chondroitin sulphate proteoglycans: key modulators of spinal cord and brain plasticity.

7 April 2017

1 reference

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RhoA-inhibiting NSAIDs promote axonal myelination after spinal cord injury

28 September 2017

1 reference

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A multi-domain fragment of Nogo-A protein is a potent inhibitor of cortical axon regeneration via Nogo receptor 1.

28 September 2017

1 reference

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Rho-associated coiled-coil-forming kinases (ROCKs): potential targets for the treatment of atherosclerosis and vascular disease

28 September 2017

1 reference

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A molecular mechanism for ibuprofen-mediated RhoA inhibition in neurons

28 September 2017

1 reference

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Rho-associated kinase II (ROCKII) limits axonal growth after trauma within the adult mouse spinal cord

28 September 2017

1 reference

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PTPsigma is a receptor for chondroitin sulfate proteoglycan, an inhibitor of neural regeneration

28 September 2017

1 reference

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Targeting a dominant negative rho kinase to neurons promotes axonal outgrowth and partial functional recovery after rat rubrospinal tract lesion

28 September 2017

1 reference

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Ibuprofen enhances recovery from spinal cord injury by limiting tissue loss and stimulating axonal growth

28 September 2017

1 reference

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Ibuprofen therapy for cystic fibrosis lung disease: revisited

28 September 2017

1 reference

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Remote activation of microglia and pro-inflammatory cytokines predict the onset and severity of below-level neuropathic pain after spinal cord injury in rats

28 September 2017

1 reference

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Potential Therapeutic Targets for PPARgamma after Spinal Cord Injury

28 September 2017

1 reference

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The N-terminal domain of Nogo-A inhibits cell adhesion and axonal outgrowth by an integrin-specific mechanism

28 September 2017

1 reference

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Spinal cord injury: time to move?

28 September 2017

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ROCK and Rho: biochemistry and neuronal functions of Rho-associated protein kinases

28 September 2017

1 reference

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White matter inhibitors in CNS axon regeneration failure

28 September 2017

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Review of treatment trials in human spinal cord injury: issues, difficulties, and recommendations

28 September 2017

1 reference

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Rho-kinase inhibition acutely augments blood flow in focal cerebral ischemia via endothelial mechanisms

28 September 2017

1 reference

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Delayed Nogo receptor therapy improves recovery from spinal cord contusion

28 September 2017

1 reference

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Extracellular regulators of axonal growth in the adult central nervous system

28 September 2017

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Targeting Rho to stimulate repair after spinal cord injury

28 September 2017

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Inhibition of Nogo: a key strategy to increase regeneration, plasticity and functional recovery of the lesioned central nervous system

28 September 2017

1 reference

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Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection

28 September 2017

1 reference

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Ephrin-B3 is a myelin-based inhibitor of neurite outgrowth

28 September 2017

1 reference

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Rho kinase, a promising drug target for neurological disorders

28 September 2017

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TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration

28 September 2017

1 reference

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Nonsteroidal Anti-Inflammatory Drugs Can Lower Amyloidogenic Aß 42 by Inhibiting Rho

28 September 2017

1 reference

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The Rho/ROCK pathway mediates neurite growth-inhibitory activity associated with the chondroitin sulfate proteoglycans of the CNS glial scar

28 September 2017

1 reference

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The Nogo-66 receptor: focusing myelin inhibition of axon regeneration

28 September 2017

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Chondroitin sulphate proteoglycans in the CNS injury response

28 September 2017

1 reference

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Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches

28 September 2017

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Truncated soluble Nogo receptor binds Nogo-66 and blocks inhibition of axon growth by myelin.

28 September 2017

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Oligodendrocyte-myelin glycoprotein (OMgp) is an inhibitor of neurite outgrowth

28 September 2017

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Animal models used in spinal cord regeneration research

28 September 2017

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Neurogenic heterotopic ossification in spinal cord injury.

28 September 2017

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Pain following spinal cord injury

28 September 2017

1 reference

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A new model of cerebral microthrombosis in rats and the neuroprotective effect of a Rho-kinase inhibitor

28 September 2017

1 reference

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Effects of nonsteroidal anti-inflammatory therapy on platelets

28 September 2017

1 reference

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Nephrotoxicity of nonsteroidal anti-inflammatory drugs: physiologic foundations and clinical implications

28 September 2017

1 reference

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NSAID induced gastrointestinal complications: the ARAMIS perspective--1997. Arthritis, Rheumatism, and Aging Medical Information System.

28 September 2017

1 reference

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Clinical pharmacokinetics of ibuprofen. The first 30 years

28 September 2017

1 reference

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Inhibition of RhoA GTPase and the subsequent activation of PTP1B protects cultured hippocampal neurons against amyloid β toxicity

28 September 2017

1 reference

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Paired immunoglobulin-like receptor B knockout does not enhance axonal regeneration or locomotor recovery after spinal cord injury.

31 May 2018

1 reference

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C3 peptide enhances recovery from spinal cord injury by improved regenerative growth of descending fiber tracts

31 May 2018

1 reference

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Validation of the weight-drop contusion model in rats: a comparative study of human spinal cord injury

31 May 2018

1 reference

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Modulation of transcription factor NF-kappaB by enantiomers of the nonsteroidal drug ibuprofen

31 May 2018

1 reference

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Spinal cord injury in the rat: treatment with bacterial lipopolysaccharide and indomethacin enhances cellular repair and locomotor function

31 May 2018

1 reference

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Prostaglandins modulate alterations of microvascular permeability, blood flow, edema and serotonin levels following spinal cord injury: an experimental study in the rat.

31 May 2018

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PirB is a functional receptor for myelin inhibitors of axonal regeneration.

31 May 2018

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Basso Mouse Scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains.

21 January 2018

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Suppression of Rho-kinase activity promotes axonal growth on inhibitory CNS substrates

21 January 2018

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Dose-dependent beneficial and detrimental effects of ROCK inhibitor Y27632 on axonal sprouting and functional recovery after rat spinal cord injury

21 January 2018

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ROCK inhibition with Y27632 activates astrocytes and increases their expression of neurite growth-inhibitory chondroitin sulfate proteoglycans

21 January 2018

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Fasudil protects hippocampal neurons against hypoxia-reoxygenation injury by suppressing microglial inflammatory responses in mice

21 January 2018

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A phase I/IIa clinical trial of a recombinant Rho protein antagonist in acute spinal cord injury.

21 January 2018

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Expression of P2X4 receptor by lesional activated microglia during formalin-induced inflammatory pain

21 January 2018

1 reference

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Inhibition of Rho-dependent pathways by Clostridium botulinum C3 protein induces a proinflammatory profile in microglia

21 January 2018

1 reference

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Improvement of cognitive deficit and neuronal damage in rats with chronic cerebral ischemia via relative long-term inhibition of rho-kinase

21 January 2018

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Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling

21 January 2018

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Purkinje cell survival in organotypic cultures: implication of Rho and its downstream effector ROCK.

21 January 2018

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Nogo receptor antagonism promotes stroke recovery by enhancing axonal plasticity.

21 January 2018

1 reference

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Blockade of Nogo-66, myelin-associated glycoprotein, and oligodendrocyte myelin glycoprotein by soluble Nogo-66 receptor promotes axonal sprouting and recovery after spinal injury.

21 January 2018

1 reference

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Neuroprotective potential of fasudil mesylate in brain ischemia-reperfusion injury of rats

21 January 2018

1 reference

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Ibuprofen effects on Alzheimer pathology and open field activity in APPsw transgenic mice

21 January 2018

1 reference

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Local inhibition of Rho signaling by cell-permeable recombinant protein BA-210 prevents secondary damage and promotes functional recovery following acute spinal cord injury

21 January 2018

1 reference

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Role of site-specific binding to plasma albumin in drug availability to brain

21 January 2018

1 reference

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Efficient testing of motor function in spinal cord injured rats

21 January 2018

1 reference

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Lamina-specific restoration of serotonergic projections after Nogo-A antibody treatment of spinal cord injury in rats.

21 January 2018

1 reference

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RhoA/Rho kinase pathway contributes to the pathogenesis of thermal hyperalgesia in diabetic mice.

21 January 2018

1 reference

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Effect of indomethacin on motor activity and spinal cord free fatty acid content after experimental spinal cord injury in rabbits.

21 January 2018

1 reference

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Brain uptake of nonsteroidal anti-inflammatory drugs: ibuprofen, flurbiprofen, and indomethacin

21 January 2018

1 reference

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Rho-kinase inhibition enhances axonal plasticity and attenuates cold hyperalgesia after dorsal rhizotomy.

21 January 2018

1 reference

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Neuroprotective properties of a protein kinase inhibitor against ischaemia-induced neuronal damage in rats and gerbils

21 January 2018

1 reference

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Wide therapeutic time window for Rho-kinase inhibition therapy in ischemic brain damage in a rat cerebral thrombosis model

21 January 2018

1 reference

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Spinal cord injury induces early and persistent lesional P2X4 receptor expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-012-1334-7

Delayed treatment with monoclonal antibody IN-1 1 week after stroke results in recovery of function and corticorubral plasticity in adult rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-012-1334-7

Effects of fasudil in acute ischemic stroke: results of a prospective placebo-controlled double-blind trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-012-1334-7

Cytoplasmic p21(Cip1/WAF1) enhances axonal regeneration and functional recovery after spinal cord injury in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-012-1334-7

Involvement of Rho-kinase in inflammatory and neuropathic pain through phosphorylation of myristoylated alanine-rich C-kinase substrate (MARCKS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-012-1334-7

Fibronectin/integrin system is involved in P2X(4) receptor upregulation in the spinal cord and neuropathic pain after nerve injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-012-1334-7

A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-012-1334-7

Abeta42-lowering nonsteroidal anti-inflammatory drugs preserve intramembrane cleavage of the amyloid precursor protein (APP) and ErbB-4 receptor and signaling through the APP intracellular domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-012-1334-7

Fasudil, a Rho kinase (ROCK) inhibitor, protects against ischemic neuronal damage in vitro and in vivo by acting directly on neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-012-1334-7

Delayed systemic Nogo-66 receptor antagonist promotes recovery from spinal cord injury.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3744771

Rho kinase inhibition enhances axonal regeneration in the injured CNS.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3744771

Rho signaling pathway targeted to promote spinal cord repair.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3744771

Locomotor recovery in spinal cord-injured rats treated with an antibody neutralizing the myelin-associated neurite growth inhibitor Nogo-A.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3744771

Rac1 mediates collapsin-1-induced growth cone collapse

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3744771

Recovery from a spinal cord injury: significance of compensation, neural plasticity, and repair

28 November 2018

1 reference

12 December 2020

Delayed intrathecal delivery of RhoA siRNA to the contused spinal cord inhibits allodynia, preserves white matter, and increases serotonergic fiber growth

1 reference

12 December 2020

Indomethacin, an inhibitor of prostaglandin synthesis attenuates alteration in spinal cord evoked potentials and edema formation after trauma to the spinal cord: an experimental study in the rat

1 reference

12 December 2020

Assessment of spinal cord pathology following trauma using early changes in the spinal cord evoked potentials: a pharmacological and morphological study in the rat

1 reference

12 December 2020

Spinal cord contusion in the rat: production of graded, reproducible, injury groups

1 reference

12 December 2020

The Nogo receptor complex: confining molecules to molecular mechanisms

1 reference

12 December 2020

Wallerian degeneration involves Rho/Rho-kinase signaling

1 reference

12 December 2020

The influence of long-term nifedipine or indomethacin therapy on neurologic recovery from experimental spinal cord injury

1 reference

12 December 2020

The metabolism of ibuprofen

1 reference

12 December 2020

Pain report and the relationship of pain to physical factors in the first 6 months following spinal cord injury

1 reference

12 December 2020

Neogenin-RGMa signaling at the growth cone is bone morphogenetic protein-independent and involves RhoA, ROCK, and PKC

1 reference

12 December 2020

Inactivation of Rho signaling pathway promotes CNS axon regeneration

1 reference

12 December 2020

Nogo-A antibody improves regeneration and locomotion of spinal cord-injured rats

1 reference

12 December 2020

Nonsteroidal anti-inflammatory drugs promote axon regeneration via RhoA inhibition

1 reference

12 December 2020

Early perifocal cell changes and edema in traumatic injury of the spinal cord are reduced by indomethacin, an inhibitor of prostaglandin synthesis. Experimental study in the rat

1 reference

12 December 2020

Genetic deletion of paired immunoglobulin-like receptor B does not promote axonal plasticity or functional recovery after traumatic brain injury

1 reference

12 December 2020

Lesional RhoA+ cell numbers are suppressed by anti-inflammatory, cyclooxygenase-inhibiting treatment following subacute spinal cord injury

1 reference

12 December 2020

10.1007/S00441-012-1334-7

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350947%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

23 January 2020

1049133849

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350947%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

PubMed publication ID

22350947

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350947%20AND%20SRC:MED&resulttype=core&format=json