(Q34461383)

2 August 2017

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title

Clinical pharmacokinetics of ibuprofen. The first 30 years (English)

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2 August 2017

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Davies NM

1

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2 August 2017

1 February 1998

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Clinical Pharmacokinetics

2 August 2017

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2 August 2017

34

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2 August 2017

101-154

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2 August 2017

2

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https://scigraph.springernature.com/pub.10.2165/00003088-199834020-00002

2 August 2017

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cites work

Synthesis, chromatographic resolution and chiroptical properties of carboxyibuprofen stereoisomers: major metabolites of ibuprofen in man

1 reference

12 December 2020

Clinical pharmacokinetics of flurbiprofen and its enantiomers

1 reference

12 December 2020

Solid-phase extraction chromatography and nuclear magnetic resonance spectrometry for the identification and isolation of drug metabolites in urine.

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of enantiomers of ibuprofen and flurbiprofen after oral administration

1 reference

12 December 2020

Binding affinity of ibuprofen in human tissues

1 reference

12 December 2020

Silica capillary gas chromatographic determination of ibuprofen in serum

1 reference

12 December 2020

Correlation of serum concentrations of ibuprofen stereoisomers with clinical response in the treatment of hip and knee osteoarthritis

1 reference

12 December 2020

The metabolic chiral inversion and dispositional enantioselectivity of the 2-arylpropionic acids and their biological consequences

1 reference

12 December 2020

Does ibuprofen affect bilirubin-albumin binding in newborn infant serum?

1 reference

12 December 2020

High-performance liquid chromatography coupled to high-field proton nuclear magnetic resonance spectroscopy: application to the urinary metabolites of ibuprofen

1 reference

12 December 2020

Isolation and characterization of rat liver microsomal R-ibuprofenoyl-CoA synthetase.

1 reference

12 December 2020

High-pressure liquid chromatographic determination of ibuprofen in plasma

1 reference

12 December 2020

The effect of octanoic acid on the binding of the enantiomers of ibuprofen and naproxen to human serum albumin: a chromatographic implication.

1 reference

12 December 2020

Effect of racemic ibuprofen dose on the magnitude and duration of platelet cyclo-oxygenase inhibition: relationship between inhibition of thromboxane production and the plasma unbound concentration of S(+)-ibuprofen.

1 reference

12 December 2020

Salicylate-NSAID interactions

1 reference

12 December 2020

Determination of ibuprofen by high-performance liquid chromatography

1 reference

12 December 2020

A Simple and Sensitive Colorimetric Determination of Ibuprofen from Plasma and Urine in Dogs after Dosing

1 reference

12 December 2020

Pathophysiologic factors affecting the pharmacokinetics of nonsteroidal antiinflammatory drugs

1 reference

12 December 2020

Update on ibuprofen: review article

1 reference

12 December 2020

Ibuprofen: a review of its pharmacological properties and therapeutic efficacy in rheumatic disorders

1 reference

12 December 2020

Stereoselective disposition of ibuprofen enantiomers in synovial fluid

1 reference

12 December 2020

Resolution of the enantiomers of ibuprofen; comparison study of diastereomeric method and chiral stationary phase method

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12 December 2020

The effect of magnesium hydroxide on the oral absorption of ibuprofen, ketoprofen and diclofenac

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12 December 2020

Human pharmacokinetics of ibuprofen enantiomers following different doses and formulations: intestinal chiral inversion.

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12 December 2020

The impact of ibuprofen on the efficacy of antihypertensive treatment with hydrochlorothiazide in elderly persons

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12 December 2020

Pharmacokinetics of the R(-) and S(+) enantiomers of ibuprofen in the serum and synovial fluid of arthritis patients

1 reference

12 December 2020

Molecular cloning and expression of a 2-arylpropionyl-coenzyme A epimerase: a key enzyme in the inversion metabolism of ibuprofen

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12 December 2020

Interaction of ibuprofen and warfarin on primary haemostasis

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12 December 2020

Stereoselective disposition of ibuprofen enantiomers in infants

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12 December 2020

The influence of ibuprofen, diclofenac and sulindac on the blood pressure lowering effect of hydrochlorothiazide.

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12 December 2020

The aspirin-ibuprofen interaction in rheumatoid arthritis

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12 December 2020

Stereoselective disposition of ibuprofen enantiomers in human cerebrospinal fluid

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12 December 2020

Clinical pharmacokinetics of naproxen

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12 December 2020

Comparison of the bioavailability of dexibuprofen administered alone or as part of racemic ibuprofen

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12 December 2020

Studies on the metabolism of 2,4'-isobutylphenylpropionic acid (ibuprofen) by gas chromatography and mass spectrometry. Dialysis fluid, a convenient medium for studies on drug metabolism

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12 December 2020

Pharmacokinetics and bioinversion of ibuprofen enantiomers in humans

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12 December 2020

Are the pharmacokinetics of ibuprofen important determinants for the drug's efficacy in postoperative pain after third molar surgery?

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12 December 2020

Ibuprofen pharmacokinetics: use of liquid chromatography with radial compression separation.

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12 December 2020

Influence of racial differences on effects of ranitidine and cimetidine on ibuprofen pharmacokinetics

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12 December 2020

Tissue distribution of ibuprofen in a fatal overdose

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12 December 2020

Interindividual variability in the enantiomeric disposition of ibuprofen following the oral administration of the racemic drug to healthy volunteers

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12 December 2020

Stereoselective disposition of ibuprofen in patients with renal dysfunction

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12 December 2020

Delirium caused by tacrine and ibuprofen interaction

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12 December 2020

Stereoselective disposition of ibuprofen enantiomers in man

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12 December 2020

Further characterization of specific drug binding sites on human serum albumin

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12 December 2020

Identification and simultaneous determination of non-steroidal anti-inflammatory drugs using high-performance liquid chromatography

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12 December 2020

Physical aspects of dexibuprofen and racemic ibuprofen

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12 December 2020

Determination of ibuprofen in serum by high-performance liquid chromatography and application to ibuprofen disposition

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12 December 2020

Pharmacokinetic analysis of the enantiomeric inversion of chiral nonsteroidal antiinflammatory drugs.

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12 December 2020

Pharmacodynamic modeling of nonsteroidal anti-inflammatory drugs: antipyretic effect of ibuprofen

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12 December 2020

[Comparative biological availability of two different ibuprofen granules]

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12 December 2020

Correlation of ibuprofen bioavailability with gastrointestinal transit by scintigraphic monitoring of 171Er-labeled sustained-release tablets

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12 December 2020

Determination of flurbiprofen and ibuprofen in dog serum with automated sample preparation

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12 December 2020

Liquid-chromatographic assay of ibuprofen enantiomers in plasma

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12 December 2020

The Analgesic Interaction of Misoprostol with Nonsteroidal Anti-Inflammatory Drugs.

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12 December 2020

Screening for acidic and neutral drugs by high performance liquid chromatography in post-mortem blood

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12 December 2020

Lack of effect of gender and oral contraceptive steroids on the pharmacokinetics of (R)-ibuprofen in humans

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12 December 2020

Effect of ibuprofen on blood pressure control by propranolol and bendrofluazide

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12 December 2020

Interaction of ibuprofen with the H-2 receptor antagonists ranitidine and cimetidine

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12 December 2020

Interaction of indomethacin and ibuprofen with lithium in manic patients under a steady-state lithium level

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12 December 2020

The effect of food on gastrointestinal (GI) transit of sustained-release ibuprofen tablets as evaluated by gamma scintigraphy

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12 December 2020

Clinical pharmacology of predisintegrated ibuprofen 800 mg tablets: an endoscopic and pharmacokinetic study

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12 December 2020

Absorption kinetics of rectally and orally administered ibuprofen

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12 December 2020

Simultaneous liquid-chromatographic determination of five nonsteroidal anti-inflammatory drugs in plasma or blood

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12 December 2020

Ibuprofen enantiomers and lipid metabolism

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12 December 2020

Mechanistic studies of the metabolic chiral inversion of (R)-ibuprofen in humans

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12 December 2020

Clinical pharmacokinetics of tiaprofenic acid and its enantiomers

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12 December 2020

Electron-Capture GLC Determination of Ibuprofen in Serum

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12 December 2020

The stereoselective uptake of ibuprofen enantiomers into adipose tissue

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12 December 2020

The effect of high-dose short-term ibuprofen on antihypertensive control with hydrochlorothiazide

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12 December 2020

High-performance liquid chromatographic determination of pimeprofen and its metabolite ibuprofen in sheep plasma and lymph

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12 December 2020

The binding of ibuprofen to plasma proteins

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12 December 2020

Albumin binding of anti-inflammatory drugs. Utility of a site-oriented versus a stoichiometric analysis.

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12 December 2020

Comparison of tissue and plasma levels of ibuprofen after oral and topical administration

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12 December 2020

The Relationship between Plasma Ibuprofen Concentrations and Toxicity in Acute Ibuprofen Overdose

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12 December 2020

Pharmacodynamics and pharmacokinetics of the profens: enantioselectivity, clinical implications, and special reference to S(+)-ibuprofen

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12 December 2020

Preliminary pharmacokinetic study of ibuprofen enantiomers after administration of a new oral formulation (ibuprofen arginine) to healthy male volunteers

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12 December 2020

Enantiospecific gas chromatographic-mass spectrometric procedure for the determination of ketoprofen and ibuprofen in synovial fluid and plasma: application to protein binding studies

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12 December 2020

Ibuprofen: plasma concentrations in man

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12 December 2020

Pharmacokinetics of ibuprofen

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12 December 2020

Simultaneous analysis of several non-steroidal anti-inflammatory drugs in human urine by high-performance liquid chromatography with normal solid-phase extraction

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12 December 2020

Lack of significant interaction between low dose methotrexate and ibuprofen or flurbiprofen in patients with arthritis

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12 December 2020

Pharmacokinetics of misoprostol in the elderly, in patients with renal failure and when coadministered with NSAID or antipyrine, propranolol or diazepam.

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12 December 2020

High-pressure liquid chromatographic determination of ibuprofen in plasma

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12 December 2020

Relative pharmacokinetics of three oral 400 mg ibuprofen dosage forms in healthy volunteers

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12 December 2020

The effect of food on the bioavailability of ibuprofen and flurbiprofen from sustained release formulations.

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12 December 2020

High-performance liquid chromatographic determination of naproxen, ibuprofen and diclofenac in plasma and synovial fluid in man

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12 December 2020

Pharmacokinetics of ibuprofen in man--III: Plasma protein binding.

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12 December 2020

Development of capillary gas chromatographic-mass spectrometric methodology for the simultaneous determination of ibuprofen and [ar-2H4]ibuprofen in serum: demonstration of kinetic equivalence in the beagle

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12 December 2020

Etodolac clinical pharmacokinetics

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12 December 2020

Methods of analysis of chiral non-steroidal anti-inflammatory drugs

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12 December 2020

A study of the absorption and tolerance of ibuprofen guaiacol ester in man after repeated oral administration

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12 December 2020

Pharmacokinetics and bioavailability of percutaneous ibuprofen

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12 December 2020

The effect of ibuprofen on serum digoxin concentrations

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12 December 2020

Renal handling and effects of S(+)-ibuprofen and R(-)-ibuprofen in the rat isolated perfused kidney

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12 December 2020

High-performance liquid chromatographic determination of ibuprofen, its metabolites and enantiomers in biological fluids

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12 December 2020

Inability of ibuprofen to alter single dose phenytoin disposition

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12 December 2020

Clinical pharmacokinetics of ketoprofen and its enantiomers

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12 December 2020

Studies on the oral absorption of ibuprofen guaiacol-ester in man

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12 December 2020

Measurement of ibuprofen in human whole blood by reversed-phase ion-paired high-performance liquid chromatography using a pH-stable polymeric column

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12 December 2020

Effects of ibuprofen enantiomers and its coenzyme A thioesters on human prostaglandin endoperoxide synthases

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12 December 2020

Intrasubject variability in bioequivalence studies illustrated by the example of ibuprofen

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12 December 2020

An alternative approach for assessment of rate of absorption in bioequivalence studies

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12 December 2020

Tissue levels of ibuprofen after fatal overdosage of ibuprofen and acetaminophen

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12 December 2020

Pharmacokinetics of ibuprofen in febrile children

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12 December 2020

Pharmacological differences between R(-)- and S(+)-ibuprofen

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12 December 2020

Assay of ibuprofen in human plasma by rapid and sensitive reversed-phase high-performance liquid chromatography:application to a single dose pharmacokinetic study

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12 December 2020

Analysis of ibuprofen in serum by capillary electrophoresis

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12 December 2020

[Pharmacokinetic variables under therapy with a nonsteroidal antirheumatic with a short half-life in patients over 65 years old]

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12 December 2020

Ibuprofen kinetics in plasma and synovial fluid of arthritic patients

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12 December 2020

Single-dose pharmacokinetics of ibuprofen and acetaminophen in febrile children

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12 December 2020

Effect of sucralfate on ibuprofen absorption in normal volunteers

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12 December 2020

Renal effects of ibuprofen, piroxicam, and sulindac in patients with asymptomatic renal failure. A prospective, randomized, crossover comparison

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12 December 2020

Enantioselective pharmacodynamics and pharmacokinetics of chiral non-steroidal anti-inflammatory drugs

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12 December 2020

A quantitative circular dichroic investigation of the binding of the enantiomers of ibuprofen and naproxen to human serum albumin

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12 December 2020

The correlation between blood levels of ibuprofen and clinical analgesic response

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12 December 2020

Concentrations of ibuprofen in serum and synovial fluid from patients with arthritis [proceedings]

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12 December 2020

GLC Determination of Ibuprofen [(±)-2-(p-Isobutylphenyl)propionic Acid] in Plasma

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12 December 2020

Effect of high-dose ibuprofen in patients with cystic fibrosis.

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12 December 2020

Influence of age on the stereoselective disposition and metabolism of ibuprofen in humans

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12 December 2020

Improved high-performance liquid chromatographic assay method for the enantiomers of ibuprofen

1 reference

12 December 2020

Method to determine the enantiomers of ibuprofen from human urine by high-performance liquid chromatography

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12 December 2020

Ibuprofen and acetaminophen kinetics when taken concurrently

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12 December 2020

S-ibuprofen versus ibuprofen-racemate. A randomized double-blind study in patients with rheumatoid arthritis

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12 December 2020

Understanding the chiral pharmacology of nonsteroidal antiinflammatory drugs in the aryl propionic acid class: S(+) ibuprofen. Overview of the symposium "update on S(+) ibuprofen" (Going/Kitzbuehl, Austria, February 2-4, 1996)

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12 December 2020

Metabolic inversion of (R)-ibuprofen. Formation of ibuprofenyl-coenzyme A

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12 December 2020

Variability in the stereoselective disposition of ibuprofen in patients with rheumatoid arthritis

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12 December 2020

Metabolic stereoisomeric inversion of ibuprofen in mammals

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12 December 2020

Pharmacokinetics of ibuprofen following a single administration of a suspension containing enteric-coated microcapsules

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12 December 2020

Effects of pH regulators used as additives on the bioavailability of ibuprofen from hard gelatin capsules

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12 December 2020

Ibuprofen and sulindac kinetics in alcoholic liver disease

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12 December 2020

The relationship between the pharmacokinetics of ibuprofen enantiomers and the dose of racemic ibuprofen in humans

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12 December 2020

The stereoselective disposition of the enantiomers of ibuprofen in blood, blister and synovial fluid

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12 December 2020

Do nizatidine and cimetidine interact with ibuprofen?

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12 December 2020

Determination of some anti-inflammatory drugs in serum by high-performance liquid chromatography

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12 December 2020

An evaluation of ibuprofen bioinversion by simulation

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12 December 2020

High-performance thin-layer chromatographic determination of ibuprofen in plasma

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12 December 2020

Anti-inflammatory (ibuprofen) drug therapy in rheumatoid arthritis- rate of response and lack of time dependency of plasma pharmacokinetics

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12 December 2020

Therapeutically relevant differences in the pharmacokinetical and pharmaceutical behavior of ibuprofen lysinate as compared to ibuprofen acid

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12 December 2020

A rapid extraction method for acidic drugs in hemolyzed blood

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12 December 2020

A major role for cytochrome P450TB (CYP2C subfamily) in the actions of non-steroidal antiinflammatory drugs

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12 December 2020

Is the formation of R-ibuprofenyl-adenylate the first stereoselective step of chiral inversion?

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12 December 2020

Lipophilic xenobiotic conjugates: the pharmacological and toxicological consequences of the participation of drugs and other foreign compounds as substrates in lipid biosynthesis

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12 December 2020

Chiral inversion of 2-arylpropionic acid non-steroidal anti-inflammatory drugs--1. In vitro studies of ibuprofen and flurbiprofen

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12 December 2020

Effect of ibuprofen on protein binding of warfarin in human serum

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12 December 2020

Separation of fifteen non-steroidal anti-inflammatory drugs using micellar electrokinetic capillary chromatography

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12 December 2020

Ibuprofen in human milk

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12 December 2020

S(+) versus racemic ibuprofen

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12 December 2020

Pharmacokinetics of ibuprofen microincapsulated granules

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12 December 2020

Column-switching techniques for high-performance liquid chromatography of ibuprofen and mefenamic acid in human serum with short-wavelength ultraviolet detection

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12 December 2020

Rapid high-performance liquid chromatographic determination of ibuprofen in human plasma

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12 December 2020

Improved high-performance liquid chromatographic assay of ibuprofen in plasma

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12 December 2020

Determination of ibuprofen in capillary and venous plasma by high-performance liquid chromatography with ultraviolet detection

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12 December 2020

Pharmacokinetics and absolute bioavailability of ibuprofen after oral administration of ibuprofen lysine in man

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12 December 2020

Effects of misoprostol or ranitidine on ibuprofen pharmacokinetics

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12 December 2020

Pharmacokinetics of two new oral formulations of ibuprofen

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12 December 2020

The effect of food or sucralfate on the bioavailability of S(+) and R(-) enantiomers of ibuprofen

1 reference

12 December 2020

Bleeding tendency, platelet function, and pharmacokinetics of ibuprofen and zidovudine in HIV(+) hemophilic men.

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12 December 2020

Chiral inversion of 2-arylpropionic acid non-steroidal anti-inflammatory drugs—II Racemization and hydrolysis of (R)- and (S)-ibuprofen-CoA thioesters

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12 December 2020

Disposition and covalent binding of ibuprofen and its acyl glucuronide in the elderly

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12 December 2020

The influence of sucralfate on ibuprofen absorption in healthy adult males

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12 December 2020

Ultrafiltration in serum protein binding determinations.

1 reference

12 December 2020

Pharmacokinetics Of Ibuprofen Enantiomers In Plasma And Suction Blister Fluid In Healthy Volunteers

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12 December 2020

Some aspects of the pharmacology, metabolism, and toxicology of ibuprofen. I. Pharmacology and metabolism

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12 December 2020

Stereochemical aspects of benzodiazepine binding to human serum albumin. I. Enantioselective high performance liquid affinity chromatographic examination of chiral and achiral binding interactions between 1,4-benzodiazepines and human serum albumin

1 reference

12 December 2020

Variability in the disposition of ibuprofen enantiomers in osteoarthritis patients

1 reference

12 December 2020

Stereoselective high-performance liquid chromatographic determination of ketoprofen, ibuprofen and fenoprofen in plasma using a chiral alpha 1-acid glycoprotein column

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12 December 2020

Activity and pharmacokinetics of a new oral dosage form of soluble ibuprofen

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12 December 2020

Pharmacokinetics of ibuprofen enantiomers after single and repeated doses in man

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12 December 2020

Ibuprofen overdose: 126 cases

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12 December 2020

Stereoselective disposition of ibuprofen enantiomers in the isolated perfused rat kidney

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12 December 2020

Binding affinity of ibuprofen to collagen and other connective tissue components

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12 December 2020

Stereoselective metabolism of anti-inflammatory 2-arylpropionates

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12 December 2020

Equipotent inhibition by R(-)-, S(+)- and racemic ibuprofen of human polymorphonuclear cell function in vitro

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12 December 2020

Gas-liquid chromatographic determination of ibuprofen in human plasma

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12 December 2020

High-performance liquid chromatographic determination of ibuprofen in human plasma and urine by direct injection

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12 December 2020

Liquid chromatographic/mass spectrometric determination of optically active drugs

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12 December 2020

[Pharmacokinetics and bioequivalence of two ibuprofen formulations]

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12 December 2020

The influence of hemodialysis on the pharmacokinetics of ibuprofen and its major metabolites

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12 December 2020

Chiral separation by capillary electrophoresis with oligosaccharides

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12 December 2020

Effects of age on the clinical pharmacokinetics of ibuprofen

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12 December 2020

Clinical pharmacokinetics of ketorolac tromethamine

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12 December 2020

Pharmacokinetics and protein binding of intravenous ibuprofen in the premature newborn infant

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12 December 2020

Pharmacokinetics of ibuprofen in man IV: absorption and disposition

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12 December 2020

Comparative bioavailability of two tablet formulations of ibuprofen.

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12 December 2020

GLC Determination of Ibuprofen [dl-2-(p-Isobutylphenyl)propionic Acid] Enantiomers in Biological Specimens

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12 December 2020

Anti-inflammatory agents: determination of ibuproxam and its metabolite humans. Correlation between bioavailability, tolerance and chemico-physical characteristics.

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12 December 2020

Disposition of ibuprofen in patients with liver cirrhosis. Stereochemical considerations

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12 December 2020

Binding of nonsteroidal anti-inflammatory agents to proteins—I. Ibuprofen-serum albumin interaction

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12 December 2020

Pharmacokinetics of ibuprofen in man: a single-dose comparison of two over-the-counter, 200 mg preparations

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12 December 2020

The binding sites on human serum albumin for some nonsteroidal antiinflammatory drugs

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12 December 2020

Quantitation of ibuprofen in biological fluids by gas chromatography--mass spectrometry

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12 December 2020

Rapid GLD determination of ibuprofen in serum

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12 December 2020

Antihypertensive activity of enalapril. Effect of ibuprofen and different salt intakes

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12 December 2020

Regioselective and stereoselective metabolism of ibuprofen by human cytochrome P450 2C.

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12 December 2020

The pharmacokinetics of ibuprofen after burn injury

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12 December 2020

Absorption and disposition of ibuprofen in the elderly

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12 December 2020

Liquid Chromatographic Determination and Plasma Concentration Profile of Optical Isomers of Ibuprofen in Humans

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12 December 2020

Determination of ibuprofen and its major metabolites in human urine by high-performance liquid chromatography

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12 December 2020

Metabolic inversion of (R)-ibuprofen. Epimerization and hydrolysis of ibuprofenyl-coenzyme A

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12 December 2020

Determination of ibuprofen in human plasma by high-performance liquid chromatography

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12 December 2020

Relative bioavailability of commercially available ibuprofen oral dosage forms in humans

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12 December 2020

Metabolic stereoisomeric inversion of 2-arylpropionic acids. On the mechanism of ibuprofen epimerization in rats

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12 December 2020

Rapid high-performance liquid chromatographic methods for the determination of overdose concentrations of some non-steroidal anti-inflammatory drugs in plasma or serum

1 reference

12 December 2020

Design of crossover microcomputer program and application on drug bioequivalence data

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12 December 2020

Percutaneous ibuprofen therapy with Trauma-Dolgit gel: bioequivalence studies

1 reference

12 December 2020

Fasting and postprandial disposition of R(-)- and S(+)-ibuprofen following oral administration of racemic drug in healthy individuals.

1 reference

12 December 2020

Pharmacokinetics of ibuprofen in man. I. Free and total area/dose relationships

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12 December 2020

Pharmacokinetic and taste evaluation of ibuprofen (Motrin) 800 mg tablets in extemporaneous solution

1 reference

12 December 2020

High-performance liquid chromatographic determination of the stereoisomeric metabolites of ibuprofen

1 reference

12 December 2020

Use of a rapid HPLC assay for determination of pharmacokinetic parameters of ibuprofen in patients with cystic fibrosis

1 reference

12 December 2020

Pharmacokinetics of S(+)- and R(-)-ibuprofen in volunteers and first clinical experience of S(+)-ibuprofen in rheumatoid arthritis.

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12 December 2020

Determination of ibuprofen in human plasma by high-performance liquid chromatography

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12 December 2020

The metabolism of ibuprofen

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12 December 2020

Transsynovial distribution of ibuprofen in arthritic patients

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12 December 2020

Pharmacological differences between the optical isomers of ibuprofen: evidence for metabolic inversion of the (—)-isomer

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12 December 2020

Isomeric inversion of ibuprofen (R)-enantiomer in humans

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12 December 2020

[Concentrations of ibuprofen and the protein and pH value of synovial fluid and plasma following oral administration of ibuprofen in patients with arthritis]

1 reference

12 December 2020

A study on the effects of ibuprofen on the metabolism of antipyrine in man.

1 reference

12 December 2020

Development and validation of a liquid chromatographic method for the quantitation of ibuprofen enantiomers in human plasma.

1 reference

12 December 2020

High-performance liquid chromatographic determination of ibuprofen and its major metabolites in biological fluids

1 reference

12 December 2020

Effect of ranitidine and cimetidine on ibuprofen pharmacokinetics

1 reference

12 December 2020

Ibuprofen bio-availability. A comparison of Brufen and Inza

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12 December 2020

Comparative human study of ibuprofen enantiomer plasma concentrations produced by two commercially available ibuprofen tablets

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12 December 2020

Phenytoin toxicity induced by interaction with ibuprofen

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12 December 2020

Rapid extraction of anti-inflammatory drugs in whole blood for HPLC analysis

1 reference

12 December 2020

Evaluation of ibuprofen dimethyl aminoethanol octyl bromide and related active metabolites in biological samples

1 reference

12 December 2020

The effect of competitive and non-linear plasma protein binding on the stereoselective disposition and metabolic inversion of ibuprofen in healthy subjects

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12 December 2020

Some biological properties of 2-(4-isobutylphenyl)-propionic acid

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12 December 2020

[Evaluation of drug concentration in tissues after percutaneous administration of non-steroidal antirheumatics]

1 reference

12 December 2020

Absorption and disposition of ibuprofen in hemodialyzed uremic patients

1 reference

12 December 2020

Simultaneous determination of codeine and ibuprofen in plasma by high-performance liquid chromatography

1 reference

12 December 2020

Pharmacokinetic evaluation of two ibuprofen-codeine combinations

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12 December 2020

Ibuprofen disposition in obese individuals

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12 December 2020

Pharmacokinetic modelling of ibuprofen

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12 December 2020

Liquid chromatographic analysis of carboxylic acids using N-(4-aminobutyl)-N-ethylisoluminol as chemiluminescent label: determination of ibuprofen in saliva

1 reference

12 December 2020

Stereoselective, competitive, and nonlinear plasma protein binding of ibuprofen enantiomers as determined in vivo in healthy subjects

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12 December 2020

Toxicological detection of ibuprofen and its metabolites in urine using gas chromatography-mass spectrometry (GC-MS).

1 reference

12 December 2020

Stereoselective disposition of ibuprofen in patients with compromised renal haemodynamics

1 reference

12 December 2020

Gas chromatographic-mass spectrometric determination of ibuprofen enantiomers in human plasma using R(-)-2,2,2-trifluoro-1-(9-anthryl)ethanol as derivatizing reagent

1 reference

12 December 2020

Protein binding of some non-steroidal anti-inflammatory drugs in rheumatoid arthritis

1 reference

12 December 2020

Comparison of the antinociception produced by two oral formulations of ibuprofen: ibuprofen effervescent vs ibuprofen tablets

1 reference

12 December 2020

High-performance liquid chromatographic determination of ibuprofen in rat and human plasma

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12 December 2020

Determination of the enantiomeric composition of ibuprofen in human plasma by high-performance liquid chromatography

1 reference

12 December 2020

[Ibuprofen pharmacokinetics in patients with liver cirrhosis]

1 reference

12 December 2020

Effect of antacid suspension on the pharmacokinetics of ibuprofen

1 reference

12 December 2020

[Kinetic studies of ibuprofen on humans. Comparative study for the determination of blood concentrations and metabolites following local and oral administration]

1 reference

12 December 2020

Gas chromatographic separation of optically active anti-inflammatory 2-arylpropionic acids using (+)- or (-)-amphetamine as derivatizing reagent

1 reference

12 December 2020

Percutaneous absorption of ibuprofen from different formulations. Comparative study with gel, hydrophilic ointment and emulsion cream

1 reference

12 December 2020

Biliary elimination of non-steroidal anti-inflammatory drugs in patients

1 reference

12 December 2020

Elevation of gastric pH with ranitidine does not affect the release characteristics of sustained release ibuprofen tablets

1 reference

12 December 2020

Evaluation of the absorption from three ibuprofen formulations

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12 December 2020

Lack of interaction between ibuprofen and warfarin

1 reference

12 December 2020

Stereospecific high-performance liquid chromatographic assay of ibuprofen: improved sensitivity and sample processing efficiency

1 reference

12 December 2020

Characterization of the protein binding of chiral drugs by high-performance affinity chromatography. Interactions of R- and S-ibuprofen with human serum albumin

1 reference

12 December 2020

Effect of age on ibuprofen pharmacokinetics and antipyretic response

1 reference

12 December 2020

Bioavailability of three commercial preparations of ibuprofen 600 mg

1 reference

12 December 2020

Enantioselective disposition of ibuprofen in elderly persons with and without renal impairment

1 reference

12 December 2020

Ibuprofen interferes with the efficacy of antihypertensive drugs. A randomized, double-blind, placebo-controlled trial of ibuprofen compared with acetaminophen

1 reference

12 December 2020

Enantiospecific determination of ibuprofen in rat plasma using chiral fluorescence derivatization reagent, (-)-2-[4-(1-aminoethyl)phenyl]-6- methoxybenzoxazole

1 reference

12 December 2020

Stereoselective plasma protein binding of ibuprofen enantiomers

1 reference

12 December 2020

Rapid HPLC-determination of ibuprofen and flurbiprofen in plasma for therapeutic drug control and pharmacokinetic applications

1 reference

12 December 2020

Intra-uterine pressure and serum ibuprofen: observations after oral administration of 400 mg ibuprofen to a patient with primary dysmenorrhoea

1 reference

12 December 2020

Liquid chromatography coupled with high-field proton NMR for profiling human urine for endogenous compounds and drug metabolites

1 reference

12 December 2020

[Drug release kinetics of ibuprofen coated granules and their in vitro-in vivo correlation].

1 reference

12 December 2020

Lack of effect of cimetidine on the pharmacokinetics of R(-)- and S(+)-ibuprofen

1 reference

12 December 2020

Rapid high-performance liquid chromatographic assay for the simultaneous analysis of non-steroidal antiinflammatory drugs in plasma

1 reference

12 December 2020

The metabolic chiral inversion of 2-arylpropionic acids—a novel route with pharmacological consequences

1 reference

12 December 2020

Isolation and characterization of major phase I and II metabolites of ibuprofen

1 reference

12 December 2020

Lack of ibuprofen secretion into human milk.

1 reference

12 December 2020

A prospective, population-based study of acute ibuprofen overdose: complications are rare and routine serum levels not warranted

1 reference

12 December 2020

High-performance liquid chromatographic assay for ibuprofen in whole blood using solid-phase extraction

1 reference

12 December 2020

Stereoselective metabolism of ibuprofen in humans: administration of R-, S- and racemic ibuprofen

1 reference

12 December 2020

2-Arylpropionyl-CoA epimerase: partial peptide sequences and tissue localization

1 reference

12 December 2020

The effect of the enantiomers of ibuprofen and flurbiprofen on the beta-oxidation of palmitate in the rat.

1 reference

12 December 2020

Ibuprofen in children with cystic fibrosis: pharmacokinetics and adverse effects

1 reference

12 December 2020

Excretion of ibuprofen into breast milk

1 reference

12 December 2020

Pharmacokinetics of ibuprofen enantiomers in humans following oral administration of tablets with different absorption rates

1 reference

12 December 2020

Concentration of ibuprofen in cervical mucus

1 reference

12 December 2020

Analysis of ibuprofen metabolites by semi-microcolumn liquid chromatography with ultraviolet absorption and pulsed amperometric detectors

1 reference

12 December 2020

Cimetidine does not alter ibuprofen kinetics after a single dose

1 reference

12 December 2020

Stereoselective disposition of ibuprofen and flurbiprofen in rats.

1 reference

12 December 2020

Enzymatic inversion at saturated carbon: nature and mechanism of the inversion of R(-) p-iso-butyl hydratropic acid

1 reference

12 December 2020

Acute and chronic effects of nonsteroidal antiinflammatory drugs on glomerular filtration rate in elderly patients

1 reference

12 December 2020

Determination of ibuprofen in human plasma by solid phase extraction and reversed-phase high-performance liquid chromatography

1 reference

12 December 2020

Studies of urinary metabolites of 2-(4-isobutylphenyl) propionic acid by gas-liquid chromatography-mass spectrometry

1 reference

12 December 2020

A pharmacokinetic comparison of ibuprofen sustained-release tablets given to young and elderly patients

1 reference

12 December 2020

Drug kinetics in burn patients

1 reference

12 December 2020

Species-dependent enantioselective glucuronidation of three 2-arylpropionic acids. Naproxen, ibuprofen, and benoxaprofen

1 reference

12 December 2020

Stereoselective and nonstereoselective effects of ibuprofen enantiomers on mitochondrial beta-oxidation of fatty acids

1 reference

12 December 2020

The effects of a salicylate, ibuprofen, and naproxen on the disposition of methotrexate in patients with rheumatoid arthritis

1 reference

12 December 2020

Rapid determination of ibuprofen in plasma by high-performance liquid chromatography

1 reference

12 December 2020

Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies

1 reference

12 December 2020

Liquid chromatographic determination of the enantiomers of ibuprofen in plasma using a chiral AGP column

1 reference

12 December 2020

The effect of colestipol and cholestyramine on ibuprofen bioavailability in man

1 reference

12 December 2020

Lack of presystemic inversion of (R)- to (S)-ibuprofen in humans

1 reference

12 December 2020

Dose-response study with ibuprofen in rheumatoid arthritis: clinical and pharmacokinetic findings

1 reference

12 December 2020

Ibuprofen levels in serum and synovial fluid

1 reference

12 December 2020

Metabolic inversion of stereoisomeric ibuprofen in man

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of ibuprofen isomers and acetaminophen in febrile children

1 reference

12 December 2020

Taurine conjugation of ibuprofen in humans and in rat liver in vitro. Relationship to metabolic chiral inversion

1 reference

12 December 2020

10.2165/00003088-199834020-00002

Identifiers

DOI

1 reference

PubMed ID

9515184

Dimensions Publication ID

2 August 2017

0 references

1 reference

PubMed ID

9515184