(Q27026407)

Michael Sacher

series ordinal

2

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language of work or name

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August 2014

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15

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PubMed

issue

8

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PubMed

page(s)

803-18

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Coats, tethers, Rabs, and SNAREs work together to mediate the intracellular destination of a transport vesicle

PubMed

cites work

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Role of tethering factors in secretory membrane traffic.

21 January 2018

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Tethering factors as organizers of intracellular vesicular traffic

21 January 2018

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Diversity in structure and function of tethering complexes: evidence for different mechanisms in vesicular transport regulation

21 January 2018

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The CORVET tethering complex interacts with the yeast Rab5 homolog Vps21 and is involved in endo-lysosomal biogenesis

21 January 2018

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The TRAPP complex: insights into its architecture and function

21 January 2018

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BET3 encodes a novel hydrophilic protein that acts in conjunction with yeast SNAREs

21 January 2018

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TRAPP, a highly conserved novel complex on the cis-Golgi that mediates vesicle docking and fusion

21 January 2018

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Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy

21 January 2018

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TRAPP I implicated in the specificity of tethering in ER-to-Golgi transport

21 January 2018

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Organization and assembly of the TRAPPII complex

21 January 2018

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Trs85 (Gsg1), a component of the TRAPP complexes, is required for the organization of the preautophagosomal structure during selective autophagy via the Cvt pathway

21 January 2018

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Identification of the novel TRAPP associated protein Tca17.

21 January 2018

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Trs85 is required for macroautophagy, pexophagy and cytoplasm to vacuole targeting in Yarrowia lipolytica and Saccharomyces cerevisiae

21 January 2018

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TRAPPC2L is a novel, highly conserved TRAPP-interacting protein

21 January 2018

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The architecture of the multisubunit TRAPP I complex suggests a model for vesicle tethering

21 January 2018

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A trs20 mutation that mimics an SEDT-causing mutation blocks selective and non-selective autophagy: a model for TRAPP III organization

21 January 2018

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The EM structure of the TRAPPIII complex leads to the identification of a requirement for COPII vesicles on the macroautophagy pathway.

21 January 2018

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Molecular architecture of the TRAPPII complex and implications for vesicle tethering

21 January 2018

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Trs20 is required for TRAPP II assembly

21 January 2018

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Trs20 is required for TRAPP III complex assembly at the PAS and its function in autophagy

21 January 2018

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The adaptor function of TRAPPC2 in mammalian TRAPPs explains TRAPPC2-associated SEDT and TRAPPC9-associated congenital intellectual disability

21 January 2018

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A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility

21 January 2018

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Network organization of the human autophagy system

21 January 2018

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C4orf41 and TTC-15 are mammalian TRAPP components with a role at an early stage in ER-to-Golgi trafficking

21 January 2018

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mTrs130 is a component of a mammalian TRAPPII complex, a Rab1 GEF that binds to COPI-coated vesicles

21 January 2018

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TRAPP stimulates guanine nucleotide exchange on Ypt1p

21 January 2018

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A Ypt32p exchange factor is a putative effector of Ypt1p

21 January 2018

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The Structural Basis for Activation of the Rab Ypt1p by the TRAPP Membrane-Tethering Complexes

21 January 2018

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TRAPPII subunits are required for the specificity switch of a Ypt-Rab GEF.

21 January 2018

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TRAPPI tethers COPII vesicles by binding the coat subunit Sec23.

21 January 2018

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Sequential interactions with Sec23 control the direction of vesicle traffic

21 January 2018

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Mutants in trs120 disrupt traffic from the early endosome to the late Golgi

21 January 2018

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Aberrant and alternative splicing in skeletal system disease

21 January 2018

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Identification of the gene (SEDL) causing X-linked spondyloepiphyseal dysplasia tarda

21 January 2018

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Identification of three novel SEDL mutations, including mutation in the rare, non-canonical splice site of exon 4

21 January 2018

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SEDLIN forms homodimers: characterisation of SEDLIN mutations and their interactions with transcription factors MBP1, PITX1 and SF1.

21 January 2018

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Sedlin controls the ER export of procollagen by regulating the Sar1 cycle

21 January 2018

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Regulation of ER-phagy by a Ypt/Rab GTPase module

21 January 2018

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ER-phagy: selective autophagy of the endoplasmic reticulum.

21 January 2018

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The unfolded protein response in secretory cell function.

21 January 2018

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The tetratricopeptide repeat: a structural motif mediating protein-protein interactions

21 January 2018

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A genetic screen in zebrafish identifies the mutants vps18, nf2 and foie gras as models of liver disease

21 January 2018

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A genome-wide RNA interference screen identifies two novel components of the metazoan secretory pathway

21 January 2018

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Recessive TRAPPC11 mutations cause a disease spectrum of limb girdle muscular dystrophy and myopathy with movement disorder and intellectual disability

21 January 2018

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TRAPPC9 mediates the interaction between p150 and COPII vesicles at the target membrane

21 January 2018

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Synbindin in extracellular signal-regulated protein kinase spatial regulation and gastric cancer aggressiveness

21 January 2018

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TRAPPC4-ERK2 interaction activates ERK1/2, modulates its nuclear localization and regulates proliferation and apoptosis of colorectal cancer cells

21 January 2018

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MAPK signaling to the early secretory pathway revealed by kinase/phosphatase functional screening

21 January 2018

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The role of ERK2 in colorectal carcinogenesis is partly regulated by TRAPPC4.

21 January 2018

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The building BLOC(k)s of lysosomes and related organelles

21 January 2018

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A mouse TRAPP-related protein is involved in pigmentation

21 January 2018

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Arabidopsis TRAPPII is functionally linked to Rab-A, but not Rab-D in polar protein trafficking in trans-Golgi network

21 January 2018

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A specific role for Arabidopsis TRAPPII in post-Golgi trafficking that is crucial for cytokinesis and cell polarity.

21 January 2018

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Trs130 participates in autophagy through GTPases Ypt31/32 in Saccharomyces cerevisiae

21 January 2018

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A BLOC-1 mutation screen reveals a novel BLOC1S3 mutation in Hermansky-Pudlak Syndrome type 8

21 January 2018

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A germline mutation in BLOC1S3/reduced pigmentation causes a novel variant of Hermansky-Pudlak syndrome (HPS8)

21 January 2018

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Structure of the Bet3-Tpc6B core of TRAPP: two Tpc6 paralogs form trimeric complexes with Bet3 and Mum2.

21 January 2018

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NIBP, a novel NIK and IKK(beta)-binding protein that enhances NF-(kappa)B activation

21 January 2018

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Homozygosity mapping in 64 Syrian consanguineous families with non-specific intellectual disability reveals 11 novel loci and high heterogeneity

21 January 2018

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A homozygous splice site mutation in TRAPPC9 causes intellectual disability and microcephaly

21 January 2018

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21 January 2018

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Identification of mutations in TRAPPC9, which encodes the NIK- and IKK-beta-binding protein, in nonsyndromic autosomal-recessive mental retardation

21 January 2018

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A truncating mutation of TRAPPC9 is associated with autosomal-recessive intellectual disability and postnatal microcephaly

21 January 2018

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Combination of linkage mapping and microarray-expression analysis identifies NF-kappaB signaling defect as a cause of autosomal-recessive mental retardation

21 January 2018

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NF-kappaB regulates spatial memory formation and synaptic plasticity through protein kinase A/CREB signaling

21 January 2018

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A requirement of nuclear factor-kappaB activation in fear-potentiated startle

21 January 2018

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Identification of novel determinants of resistance to lapatinib in ERBB2-amplified cancers

21 January 2018

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Expression and function of NIK- and IKK2-binding protein (NIBP) in mouse enteric nervous system

21 January 2018

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The PEG13-DMR and brain-specific enhancers dictate imprinted expression within the 8q24 intellectual disability risk locus

21 January 2018

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Moonlighting proteins: an intriguing mode of multitasking

21 January 2018

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Multiple mutations and cancer

21 January 2018

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The wobbler mouse, an ALS animal model

21 January 2018

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Mutation of Vps54 causes motor neuron disease and defective spermiogenesis in the wobbler mouse

21 January 2018

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Structural basis for the wobbler mouse neurodegenerative disorder caused by mutation in the Vps54 subunit of the GARP complex

21 January 2018

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VPS53 mutations cause progressive cerebello-cerebral atrophy type 2 (PCCA2).

21 January 2018

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Molecular organization of the COG vesicle tethering complex

21 January 2018

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Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function

21 January 2018

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Subunit architecture of the conserved oligomeric Golgi complex

21 January 2018

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Conserved oligomeric Golgi complex subunit 1 deficiency reveals a previously uncharacterized congenital disorder of glycosylation type II.

21 January 2018

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A new inborn error of glycosylation due to a Cog8 deficiency reveals a critical role for the Cog1-Cog8 interaction in COG complex formation

21 January 2018

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Fatal outcome due to deficiency of subunit 6 of the conserved oligomeric Golgi complex leading to a new type of congenital disorders of glycosylation

21 January 2018

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Deficiency in COG5 causes a moderate form of congenital disorders of glycosylation.

21 January 2018

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Golgi function and dysfunction in the first COG4-deficient CDG type II patient

21 January 2018

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Mutation of the COG complex subunit gene COG7 causes a lethal congenital disorder

21 January 2018

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A novel syndrome of hypohidrosis and intellectual disability is linked to COG6 deficiency

21 January 2018

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Synbindin, A novel syndecan-2-binding protein in neuronal dendritic spines

21 January 2018

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A novel 16-kilodalton cellular protein physically interacts with and antagonizes the functional activity of c-myc promoter-binding protein 1

21 January 2018

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Modulation of Human Luteinizing Hormone β Gene Transcription by MIP-2A

21 January 2018

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Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

21 January 2018

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

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Genomic investigation of alpha-synuclein multiplication and parkinsonism

21 January 2018

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Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

21 January 2018

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Yeast cells provide insight into alpha-synuclein biology and pathobiology

21 January 2018

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α-Synuclein impairs macroautophagy: implications for Parkinson's disease.

21 January 2018

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Atg9 vesicles recruit vesicle-tethering proteins Trs85 and Ypt1 to the autophagosome formation site

21 January 2018

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mBet3p is required for homotypic COPII vesicle tethering in mammalian cells

21 January 2018

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Cranio-lenticulo-sutural dysplasia is caused by a SEC23A mutation leading to abnormal endoplasmic-reticulum-to-Golgi trafficking

21 January 2018

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Cranio-lenticulo-sutural dysplasia associated with defects in collagen secretion

21 January 2018

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The [corrected] SEC23-SEC31 [corrected] interface plays critical role for export of procollagen from the endoplasmic reticulum

21 January 2018

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Secretory COPII coat component Sec23a is essential for craniofacial chondrocyte maturation

21 January 2018

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Sec24D-dependent transport of extracellular matrix proteins is required for zebrafish skeletal morphogenesis

21 January 2018

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Efficient coupling of Sec23-Sec24 to Sec13-Sec31 drives COPII-dependent collagen secretion and is essential for normal craniofacial development.

21 January 2018

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COPII-coated vesicles: flexible enough for large cargo?

21 January 2018

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Mutations in a Sar1 GTPase of COPII vesicles are associated with lipid absorption disorders

21 January 2018

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COPII and the regulation of protein sorting in mammals

21 January 2018

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Mutations affecting the secretory COPII coat component SEC23B cause congenital dyserythropoietic anemia type II.

21 January 2018

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Mutation in archain 1, a subunit of COPI coatomer complex, causes diluted coat color and Purkinje cell degeneration

21 January 2018

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