(Q27074035)

English

7-hydroxystaurosporine

chemical compound

UCN 01
UCN-01
7-Hydroxystaurosporine
KRX-0601
KRX0601

In more languages

Statements

type of chemical entity

0 references

indolo[2,3-a]carbazole alkaloid

0 references

482.195±0 dalton

1 reference

language of work or name

7-Hydroxystaurosporine (English)

19 October 2016

stereoisomer of

1 reference

based on heuristic

inferred from InChI

chemical formula

C₂₈H₂₆N₄O₄

1 reference

language of work or name

7-Hydroxystaurosporine (English)

19 October 2016

canonical SMILES

CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)C(NC6=O)O)NC)OC

1 reference

language of work or name

7-Hydroxystaurosporine (English)

19 October 2016

isomeric SMILES

C[C@@]12[C@@H]([C@@H](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)[C@H](NC6=O)O)NC)OC

1 reference

language of work or name

7-Hydroxystaurosporine (English)

19 October 2016

2 references

UCN-01, a selective inhibitor of protein kinase C from Streptomyces.

UCN-01 and UCN-02, new selective inhibitors of protein kinase C. II. Purification, physico-chemical properties, structural determination and biological activities

Streptomyces longisporoflavus

1 reference

Further minor metabolites of staurosporine produced by a Streptomyces longisporoflavus strain

subject has role

protein kinase inhibitors

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

0 references

Identifiers

InChI=1S/C28H26N4O4/c1-28-25(35-3)15(29-2)12-18(36-28)31-16-10-6-4-8-13(16)19-21-22(27(34)30-26(21)33)20-14-9-5-7-11-17(14)32(28)24(20)23(19)31/h4-11,15,18,25,27,29,34H,12H2,1-3H3,(H,30,33)/t15-,18-,25-,27-,28+/m1/s1

1 reference

language of work or name

7-Hydroxystaurosporine (English)

19 October 2016

PBCZSGKMGDDXIJ-HQCWYSJUSA-N

1 reference

language of work or name

7-Hydroxystaurosporine (English)

19 October 2016

CAS Registry Number

1 reference

Global Substance Registration System

language of work or name

7-hydroxystaurosporine (English)

19 October 2016

1 reference

language of work or name

(2S,3R,4R,6R,18R)-18-Hydroxy-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1~2,6~.0~7,28~.0~8,13~.0~15,19~.0~20,27~.0~21,26~]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-16-one (English)

19 October 2016

1 reference

language of work or name

7-Hydroxystaurosporine (English)

19 October 2016

1 reference

language of work or name

CHEMBL1236539 (English)

19 October 2016

UniChem compound ID

1 reference

DSSTox substance ID

1 reference

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

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Guide to Pharmacology Ligand ID

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

7-hydroxystaurosporine (English)

19 October 2016

MeSH descriptor ID

1 reference

Medical Subject Headings

MeSH descriptor ID

14 March 2018

1 reference

language of work or name

7-Hydroxystaurosporine (English)

19 October 2016

1 reference

Global Substance Registration System

language of work or name

7-hydroxystaurosporine (English)

19 October 2016

Natural Product Atlas ID

1 reference

based on heuristic

inferred from InChIKey

Probes And Drugs ID

0 references

0 references

PDB structure ID

1 reference

Protein Data Bank

PDB structure ID

language of work or name

1PKD (English)

19 October 2016

1 reference

Protein Data Bank

PDB structure ID

language of work or name

1OKZ (English)

19 October 2016

1 reference

Protein Data Bank

PDB structure ID

language of work or name

1NVQ (English)

19 October 2016

Sitelinks

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Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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