Wikidata

(Q27081513)

English

larotrectinib

chemical compound

  • (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide
  • example 14 [US8865698 B2]
  • larotrectinib (proposed INN)
  • LOXO-101
  • ARRY-470
  • Larotrectinib
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No description defined

Statements

chemical structure
Larotrectinib.svg
512 × 286; 7 KB
0 references
mass
428.17723 dalton
1 reference
stated in
PubChem
PubChem CID
46188928
language of work or name
English
title
LOXO-101 (English)
retrieved
3 October 2016
chemical formula
C₂₁H₂₂F₂N₆O₂
1 reference
stated in
PubChem
PubChem CID
46188928
language of work or name
English
title
LOXO-101 (English)
retrieved
20 November 2016
canonical SMILES
C1CC(N(C1)C2=NC3=C(C=NN3C=C2)NC(=O)N4CCC(C4)O)C5=C(C=CC(=C5)F)F
1 reference
stated in
PubChem
PubChem CID
46188928
language of work or name
English
title
LOXO-101 (English)
retrieved
20 November 2016
isomeric SMILES
C1C[C@@H](N(C1)C2=NC3=C(C=NN3C=C2)NC(=O)N4CC[C@@H](C4)O)C5=C(C=CC(=C5)F)F
1 reference
stated in
PubChem
PubChem CID
46188928
language of work or name
English
title
LOXO-101 (English)
retrieved
20 November 2016

Identifiers

ChemSpider ID
44210503
1 reference
stated in
ChemSpider
ChemSpider ID
44210503
language of work or name
English
title
(3S)-N-{5-[(2R)-2-(2,5-Difluorophenyl)-1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-3-yl}-3-hydroxy-1-pyrrolidinecarboxamide (English)
retrieved
20 November 2016
LiverTox ID
Larotrectinib
0 references
RxNorm ID
2105628
0 references
 
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