(Q27310160)

26854665

26 June 2017

title

Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation (English)

1 reference

26 June 2017

0 references

1

1 reference

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12 June 2020

Michael O'Donnell

6

1 reference

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12 June 2020

Huilin Li

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26854665%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

author name string

Lin Bai

2

1 reference

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12 June 2020

Jingchuan Sun

3

1 reference

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12 June 2020

Roxana Georgescu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26854665%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Jun Liu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26854665%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

language of work or name

English

0 references

publication date

8 February 2016

1 reference

26854665

Nature Structural & Molecular Biology

26 June 2017

published in

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12 June 2020

volume

23

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12 June 2020

issue

3

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12 June 2020

page(s)

217-224

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26854665%20AND%20SRC:MED&resulttype=core&format=json

The architecture of a eukaryotic replisome.

12 June 2020

cites work

1 reference

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Structure of the eukaryotic MCM complex at 3.8 Å

21 March 2017

1 reference

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A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome.

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

A conserved MCM single-stranded DNA binding element is essential for replication initiation

21 March 2017

1 reference

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Structure of the Yeast Mitochondrial Large Ribosomal Subunit

21 March 2017

1 reference

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Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM.

21 March 2017

1 reference

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The hexameric helicase DnaB adopts a nonplanar conformation during translocation.

21 March 2017

1 reference

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How a DNA Polymerase Clamp Loader Opens a Sliding Clamp

21 March 2017

1 reference

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Characterization and structure determination of the Cdt1 binding domain of human minichromosome maintenance (Mcm) 6

21 March 2017

1 reference

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Structure of RecJ Exonuclease Defines Its Specificity for Single-stranded DNA

21 March 2017

1 reference

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

21 March 2017

1 reference

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MolProbity: all-atom structure validation for macromolecular crystallography

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

The Mechanism of ATP-Dependent Primer-Template Recognition by a Clamp Loader Complex

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Crystal structure of a near-full-length archaeal MCM: Functional insights for an AAA+ hexameric helicase

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Crystal structure of the GINS complex and functional insights into its role in DNA replication

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Crystal structure of the human GINS complex

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Structure of the human GINS complex and its assembly and functional interface in replication initiation

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Structure of the Rho transcription terminator: mechanism of mRNA recognition and helicase loading

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

The crystal structure of exonuclease RecJ bound to Mn2+ ion suggests how its characteristic motifs are involved in exonuclease activity

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Crystal structure of T7 gene 4 ring helicase indicates a mechanism for sequential hydrolysis of nucleotides

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Towards automated crystallographic structure refinement with phenix.refine

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Coot: model-building tools for molecular graphics

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

UCSF Chimera--a visualization system for exploratory research and analysis

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

The structural basis for MCM2-7 helicase activation by GINS and Cdc45.

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Structural analysis of a eukaryotic sliding DNA clamp-clamp loader complex

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

RELION: implementation of a Bayesian approach to cryo-EM structure determination

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Glycosyltransferases: structures, functions, and mechanisms

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Dynamic personalities of proteins

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Structure and mechanism of helicases and nucleic acid translocases

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Intrinsic dynamics of an enzyme underlies catalysis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

The Energy Landscapes and Motions of Proteins

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Two promising future developments of cryo-EM: capturing short-lived states and mapping a continuum of states of a macromolecule

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

De novo protein structure determination from near-atomic-resolution cryo-EM maps

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Cdc45 (cell division cycle protein 45) guards the gate of the Eukaryote Replisome helicase stabilizing leading strand engagement.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Analysis of the crystal structure of an active MCM hexamer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

DNA binding polarity, dimerization, and ATPase ring remodeling in the CMG helicase of the eukaryotic replisome.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2-7 onto DNA

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Structure and evolutionary origins of the CMG complex

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

MCM structure and mechanics: what we have learned from archaeal MCM.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

ATP-dependent conformational dynamics underlie the functional asymmetry of the replicative helicase from a minimalist eukaryote

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

The CMG (CDC45/RecJ, MCM, GINS) complex is a conserved component of the DNA replication system in all archaea and eukaryotes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Efficient coupling of ATP hydrolysis to translocation by RecQ helicase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Selective bypass of a lagging strand roadblock by the eukaryotic replicative DNA helicase.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

The nuts and bolts of ring-translocase structure and mechanism

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

The Mcm complex: unwinding the mechanism of a replicative helicase.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Mechanism of DNA translocation in a replicative hexameric helicase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

ATP hydrolysis stimulates binding and release of single stranded DNA from alternating subunits of the dimeric E. coli Rep helicase: implications for ATP-driven helicase translocation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Structural and functional insights into the DNA replication factor Cdc45 reveal an evolutionary relationship to the DHH family of phosphoesterases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Regulated eukaryotic DNA replication origin firing with purified proteins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Semi-automated selection of cryo-EM particles in RELION-1.3.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

DNA replication: making two forks from one prereplication complex

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Mechanism of ATP-dependent translocation of E.coli UvrD monomers along single-stranded DNA.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4812828

Activation of the MCM2-7 helicase by association with Cdc45 and GINS proteins.

31 May 2018

1 reference

MCM forked substrate specificity involves dynamic interaction with the 5'-tail.

21 January 2018

1 reference

Cdc45: the missing RecJ ortholog in eukaryotes?

21 January 2018

1 reference

Bacillus stearothermophilus PcrA monomer is a single-stranded DNA translocase but not a processive helicase in vitro.

21 January 2018

1 reference

ATPase site architecture and helicase mechanism of an archaeal MCM.

21 January 2018

1 reference

CTFFIND4: Fast and accurate defocus estimation from electron micrographs.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1038/NSMB.3170

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26854665%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 June 2020

1053369012

0 references

OpenCitations bibliographic resource ID

2524831

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2524831

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26854665%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

26854665

1 reference