(Q27312482)

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CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection

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CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection (English)

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Mycobacterium tuberculosis

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object named as

Roland Brosch

11

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author name string

Fadel Sayes

1

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Alexandre Pawlik

2

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Wafa Frigui

3

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Matthias I Gröschel

4

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Samuel Crommelynck

5

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Catherine Fayolle

6

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Felipe Cia

7

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Gregory J Bancroft

8

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Daria Bottai

9

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Claude Leclerc

10

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Laleh Majlessi

12

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language of work or name

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publication date

July 2016

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12

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7

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e1005770

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copyright license

Creative Commons Attribution 4.0 International

28 July 2016

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April 2022 Public Data File from Crossref

copyright status

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Conserved immune recognition hierarchy of mycobacterial PE/PPE proteins during infection in natural hosts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

21 March 2017

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

21 March 2017

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

21 March 2017

High content phenotypic cell-based visual screen identifies Mycobacterium tuberculosis acyltrehalose-containing glycolipids involved in phagosome remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

21 March 2017

The transcriptional regulator Rv0485 modulates the expression of a pe and ppe gene pair and is required for Mycobacterium tuberculosis virulence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

21 March 2017

Expression, characterization and subcellular localization of the Mycobacterium tuberculosis PPE gene Rv1917c

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

21 March 2017

Evidence that mycobacterial PE_PGRS proteins are cell surface constituents that influence interactions with other cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

21 March 2017

CD4 T Cell-Derived IFN-γ Plays a Minimal Role in Control of Pulmonary Mycobacterium tuberculosis Infection and Must Be Actively Repressed by PD-1 to Prevent Lethal Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

ESAT-6-dependent cytosolic pattern recognition drives noncognate tuberculosis control in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

The BCG Strain Pool: Diversity Matters

1 reference

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28 September 2017

Mycobacterial Pan-Genome Analysis Suggests Important Role of Plasmids in the Radiation of Type VII Secretion Systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Variable Virulence and Efficacy of BCG Vaccine Strains in Mice and Correlation With Genome Polymorphisms

1 reference

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28 September 2017

Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Increased protective efficacy of recombinant BCG strains expressing virulence-neutral proteins of the ESX-1 secretion system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Phylogeny to function: PE/PPE protein evolution and impact on Mycobacterium tuberculosis pathogenicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

T cells and adaptive immunity to Mycobacterium tuberculosis in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

The onset of adaptive immunity in the mouse model of tuberculosis and the factors that compromise its expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Release of mycobacterial antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Cytosolic access of Mycobacterium tuberculosis: critical impact of phagosomal acidification control and demonstration of occurrence in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

The Recombinant BCG ΔureC::hly Vaccine Targets the AIM2 Inflammasome to Induce Autophagy and Inflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Cutting edge: control of Mycobacterium tuberculosis infection by a subset of lung parenchyma-homing CD4 T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Sequence diversity in the pe_pgrs genes of Mycobacterium tuberculosis is independent of human T cell recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Harnessing local and systemic immunity for vaccines against tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3+CCR6+ Th1 subset

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

PPE38 modulates the innate immune response and is required for Mycobacterium marinum virulence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Mycobacterial secretion systems ESX-1 and ESX-5 play distinct roles in host cell death and inflammasome activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

A recombinant Mycobacterium smegmatis induces potent bactericidal immunity against Mycobacterium tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Role of innate cytokines in mycobacterial infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Rv3615c is a highly immunodominant RD1 (Region of Difference 1)-dependent secreted antigen specific for Mycobacterium tuberculosis infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Mycobacterial PE/PPE proteins at the host-pathogen interface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

The second Geneva Consensus: Recommendations for novel live TB vaccines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

ESX/type VII secretion systems and their role in host-pathogen interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Multifunctional, high-level cytokine-producing Th1 cells in the lung, but not spleen, correlate with protection against Mycobacterium tuberculosis aerosol challenge in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Characterization of T-cell immunogenicity of two PE/PPE proteins of Mycobacterium tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Evaluation of T-cell responses to peptides with MHC class I-binding motifs derived from PE_PGRS 33 protein of Mycobacterium tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Should a new tuberculosis vaccine be administered intranasally?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Protective immunity to tuberculosis with Ag85B-ESAT-6 in a synthetic cationic adjuvant system IC31.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

A Mycobacterium avium PPE gene is associated with the ability of the bacterium to grow in macrophages and virulence in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

ESAT-6 proteins: protective antigens and virulence factors?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Protective effect of a tuberculosis subunit vaccine based on a fusion of antigen 85B and ESAT-6 in the aerosol guinea pig model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

PPE Antigen Rv2430c of Mycobacterium tuberculosis Induces a Strong B-Cell Response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

The PE multigene family: a 'molecular mantra' for mycobacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Comparative immune response to PE and PE_PGRS antigens of Mycobacterium tuberculosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

28 September 2017

Specific T cell frequency and cytokine expression profile do not correlate with protection against tuberculosis after bacillus Calmette-Guérin vaccination of newborns

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965174

31 May 2018

Strong immunogenicity and cross-reactivity of Mycobacterium tuberculosis ESX-5 type VII secretion: encoded PE-PPE proteins predicts vaccine potential

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1005770

21 January 2018

Influence of ESAT-6 secretion system 1 (RD1) of Mycobacterium tuberculosis on the interaction between mycobacteria and the host immune system

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1005770

21 January 2018

Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1005770

21 January 2018

Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1005770

21 January 2018

Mycobacterium tuberculosis Meets the Cytosol: The Role of cGAS in Anti-mycobacterial Immunity.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1005770

21 January 2018

Type VII secretion--mycobacteria show the way.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1005770

21 January 2018

Induction of protective immunity against Mycobacterium tuberculosis by delivery of ESX antigens into airway dendritic cells.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1005770

21 January 2018

Regulation of the Mycobacterium tuberculosis PE/PPE genes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1005770

21 January 2018

Double- and monofunctional CD4⁺ and CD8⁺ T-cell responses to Mycobacterium tuberculosis DosR antigens and peptides in long-term latently infected individuals.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1005770

21 January 2018

Pattern and diversity of cytokine production differentiates between Mycobacterium tuberculosis infection and disease

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1005770

21 January 2018

A multistage tuberculosis vaccine that confers efficient protection before and after exposure.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1005770

21 January 2018

Mucosal administration of Ag85B-ESAT-6 protects against infection with Mycobacterium tuberculosis and boosts prior bacillus Calmette-Guerin immunity.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1005770

21 January 2018

Tuberculosis subunit vaccination provides long-term protective immunity characterized by multifunctional CD4 memory T cells

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1005770

21 January 2018

Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1005770

21 January 2018

Mycobacterial PE, PPE and ESX clusters: novel insights into the secretion of these most unusual protein families

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1005770

21 January 2018

Dominant TNF-α+ Mycobacterium tuberculosis–specific CD4+ T cell responses discriminate between latent infection and active disease

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1005770

21 January 2018

PE_PGRS30 is required for the full virulence of Mycobacterium tuberculosis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1005770

21 January 2018

A specific secretion system mediates PPE41 transport in pathogenic mycobacteria

1 reference

https://pubmed.ncbi.nlm.nih.gov/27467705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PPE and PE_PGRS proteins ofMycobacterium marinumare transported via the type VII secretion system ESX-5

1 reference

https://pubmed.ncbi.nlm.nih.gov/27467705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4 T cells producing IFN-gamma in the lungs of mice challenged with mycobacteria express a CD27-negative phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/27467705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of interferon gamma-secreting CD8+ T lymphocytes in humans specific for three PE/PPE proteins of Mycobacterium tuberculosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/27467705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bacterial proteins with cleaved or uncleaved signal peptides of the general secretory pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/27467705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PPAT.1005770

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

release_55hff65phrhi7ozt5rwbm6sloa

1 reference

https://api.fatcat.wiki/v0/release/55hff65phrhi7ozt5rwbm6sloa

24 November 2022

based on heuristic

mapped directly with Wikidata item

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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