(Q27314486)

26 June 2017

title

TPX2 Inhibits Eg5 by Interactions with Both Motor and Microtubule (English)

1 reference

26 June 2017

0 references

0 references

Janel Titus

3

1 reference

26 June 2017

Patricia Wadsworth

5

1 reference

26 June 2017

Sai K Balchand

1

1 reference

26 June 2017

Barbara J Mann

2

1 reference

26 June 2017

Jennifer L Ross

4

1 reference

26 June 2017

language of work or name

English

0 references

publication date

27 May 2015

1 reference

Journal of Biological Chemistry

26 June 2017

published in

1 reference

26 June 2017

volume

290

1 reference

26 June 2017

issue

28

1 reference

26 June 2017

page(s)

17367-17379

1 reference

describes a project that uses

26 June 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4498074/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

TPX2 regulates the localization and activity of Eg5 in the mammalian mitotic spindle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

A nonmotor microtubule binding site in kinesin-5 is required for filament crosslinking and sliding

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

The conserved L5 loop establishes the pre-powerstroke conformation of the Kinesin-5 motor, eg5

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

Single molecule imaging reveals differences in microtubule track selection between Kinesin motors

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

Microtubule cross-linking triggers the directional motility of kinesin-5

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

Spindle pole regulation by a discrete Eg5-interacting domain in TPX2

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

Individual dimers of the mitotic kinesin motor Eg5 step processively and support substantial loads in vitro

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

Protein measurement with the Folin phenol reagent

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

Structural basis of Aurora-A activation by TPX2 at the mitotic spindle

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

Human TPX2 is required for targeting Aurora-A kinase to the spindle

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

TPX2, A novel xenopus MAP involved in spindle pole organization

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

She1-mediated inhibition of dynein motility along astral microtubules promotes polarized spindle movements

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

Directional switching of the kinesin Cin8 through motor coupling

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

hTPX2 is required for normal spindle morphology and centrosome integrity during vertebrate cell division

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

Phosphorylation of microtubule-associated proteins MAP2 and MAP4 by the protein kinase p110mark. Phosphorylation sites and regulation of microtubule dynamics

21 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

21 March 2017

https://api.crossref.org/works/10.1074%2FJBC.M114.612903

Differential regulation of dynein and kinesin motor proteins by tau

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

The Kinesin-12 Kif15 is a processive track-switching tetramer

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

The microtubule-binding protein ensconsin is an essential cofactor of kinesin-1

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

The microtubule-binding protein Cep170 promotes the targeting of the kinesin-13 depolymerase Kif2b to the mitotic spindle.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

Tau protein diffuses along the microtubule lattice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

Dynamic reorganization of Eg5 in the mammalian spindle throughout mitosis requires dynein and TPX2.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

Directionality of individual kinesin-5 Cin8 motors is modulated by loop 8, ionic strength and microtubule geometry.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

Poleward transport of TPX2 in the mammalian mitotic spindle requires dynein, Eg5, and microtubule flux

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

The fluorescent protein palette: tools for cellular imaging

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

The homotetrameric kinesin-5 KLP61F preferentially crosslinks microtubules into antiparallel orientations

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

A novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

Mechanisms of mitotic spindle assembly and function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

XMAP215 is a processive microtubule polymerase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

Tracking single Kinesin molecules in the cytoplasm of mammalian cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

Load-dependent release limits the processive stepping of the tetrameric Eg5 motor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

Allosteric inhibition of kinesin-5 modulates its processive directional motility.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

Molecular requirements for kinetochore-associated microtubule formation in mammalian cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

S-trityl-L-cysteine is a reversible, tight binding inhibitor of the human kinesin Eg5 that specifically blocks mitotic progression.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

Engineering the processive run length of the kinesin motor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

The C-terminus of tubulin increases cytoplasmic dynein and kinesin processivity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

Preparation of modified tubulins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

Localization of the kinesin-like protein Xklp2 to spindle poles requires a leucine zipper, a microtubule-associated protein, and dynein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498074

A combined approach for the localization and tandem affinity purification of protein complexes from metazoans.

31 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M114.612903

Drosophila ensconsin promotes productive recruitment of Kinesin-1 to microtubules

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M114.612903

Interaction of brain cytoplasmic dynein and MAP2 with a common sequence at the C terminus of tubulin

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M114.612903

Regulation ofXenopusAurora A Activation by TPX2

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26018074

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M114.612903

1 reference

OpenCitations bibliographic resource ID

26 June 2017

2277565

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2277565

1 reference