(Q40310383)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16507573%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

S-trityl-L-cysteine is a reversible, tight binding inhibitor of the human kinesin Eg5 that specifically blocks mitotic progression (English)

1 reference

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17 January 2020

0 references

4

1 reference

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17 January 2020

Robert A Cross

6

1 reference

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17 January 2020

Frank Kozielski

9

1 reference

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17 January 2020

author name string

Dimitrios A Skoufias

1

1 reference

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17 January 2020

Salvatore DeBonis

2

1 reference

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17 January 2020

Yasmina Saoudi

3

1 reference

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17 January 2020

Isabelle Crevel

5

1 reference

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17 January 2020

Richard H Wade

7

1 reference

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17 January 2020

David Hackney

8

1 reference

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17 January 2020

language of work or name

English

0 references

publication date

28 February 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16507573%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

17 January 2020

published in

1 reference

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17 January 2020

volume

281

1 reference

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17 January 2020

issue

26

1 reference

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17 January 2020

page(s)

17559-17569

1 reference

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Past and future of the mitotic spindle as an oncology target

17 January 2020

cites work

1 reference

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Mitotic kinesins: prospects for antimitotic drug discovery.

21 January 2018

1 reference

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A standardized kinesin nomenclature

21 January 2018

1 reference

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Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

21 January 2018

1 reference

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Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

21 January 2018

1 reference

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A novel action of terpendole E on the motor activity of mitotic Kinesin Eg5.

21 January 2018

1 reference

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HR22C16: a potent small-molecule probe for the dynamics of cell division

21 January 2018

1 reference

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Antitumor activity of a kinesin inhibitor

21 January 2018

1 reference

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Kinesin spindle protein (KSP) inhibitors. Part 1: The discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSP.

21 January 2018

1 reference

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Determining the position of the cell division plane

21 January 2018

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Interaction of the mitotic inhibitor monastrol with human kinesin Eg5.

21 January 2018

1 reference

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Evidence that monastrol is an allosteric inhibitor of the mitotic kinesin Eg5

21 January 2018

1 reference

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Mechanism of inhibition of human KSP by monastrol: insights from kinetic analysis and the effect of ionic strength on KSP inhibition

21 January 2018

1 reference

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Identification of the protein binding region of S-trityl-L-cysteine, a new potent inhibitor of the mitotic kinesin Eg5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511735200

The overall conformation of conventional kinesins studied by small angle X-ray and neutron scattering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511735200

Crystal structure of the motor domain of the human kinetochore protein CENP-E

21 January 2018

1 reference

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Preparation of tubulin from brain.

21 January 2018

1 reference

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Kinetics of the reversible inhibition of enzyme-catalysed reactions by tight-binding inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511735200

Monoclonal antibodies to mitotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511735200

Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility

21 January 2018

1 reference

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A novel brain ATPase with properties expected for the fast axonal transport motor

21 January 2018

1 reference

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CENP-E is a putative kinetochore motor that accumulates just before mitosis

21 January 2018

1 reference

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A plus-end-directed motor enzyme that moves antiparallel microtubules in vitro localizes to the interzone of mitotic spindles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511735200

cDNA cloning, expression pattern, genomic structure and chromosomal location of RAB6KIFL, a human kinesin-like gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511735200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511735200

Cloning and expression of human mitotic centromere-associated kinesin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511735200

Antagonistic microtubule-sliding motors position mitotic centrosomes in Drosophila early embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511735200

Functional coordination of three mitotic motors in Drosophila embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511735200

Length control of the metaphase spindle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511735200

Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511735200

The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK

21 January 2018

1 reference

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Mitotic kinesin inhibitors induce mitotic arrest and cell death in Taxol-resistant and -sensitive cancer cells.

21 January 2018

1 reference

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Enhanced antitumor activity of irofulven in combination with antimitotic agents

21 January 2018

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Effects of a series of organosulfur compounds on mitotic arrest and induction of apoptosis in colon cancer cells

21 January 2018

1 reference

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