(Q44118421)

30 November 2017

title

Enhanced antitumor activity of irofulven in combination with antimitotic agents (English)

1 reference

30 November 2017

Michael J Kelner

1

1 reference

30 November 2017

Trevor C McMorris

2

1 reference

30 November 2017

Rafael J Rojas

3

1 reference

30 November 2017

Nicole A Trani

4

1 reference

30 November 2017

Tami R Velasco

5

1 reference

30 November 2017

Leita A Estes

6

1 reference

30 November 2017

Pharnuk Suthipinijtham

7

1 reference

30 November 2017

publication date

1 August 2002

1 reference

Investigational New Drugs

30 November 2017

published in

1 reference

30 November 2017

volume

20

1 reference

30 November 2017

issue

3

1 reference

30 November 2017

page(s)

271-279

1 reference

Computerized quantitation of synergism and antagonism of taxol, topotecan, and cisplatin against human teratocarcinoma cell growth: a rational approach to clinical protocol design

30 November 2017

cites work

1 reference

12 December 2020

Activity of irofulven (6-hydroxymethylacylfulvene) in the treatment of glioblastoma multiforme-derived xenografts in athymic mice

1 reference

12 December 2020

Characterization of illudin S sensitivity in DNA repair-deficient Chinese hamster cells. Unusually high sensitivity of ERCC2 and ERCC3 DNA helicase-deficient mutants in comparison to other chemotherapeutic agents

1 reference

12 December 2020

Cytotoxic effects of MGI 114 are independent of tumor p53 or p21 expression.

1 reference

12 December 2020

Characterization of MGI 114 (HMAF) histiospecific toxicity in human tumor cell lines

1 reference

12 December 2020

MGI 114: augmentation of antitumor activity when combined with topotecan.

1 reference

12 December 2020

Microscopic metastasis of a human lung carcinoma cell line in athymic nude mice: isolation of a metastatic variant

1 reference

12 December 2020

Phase I and pharmacokinetic study of irofulven, a novel mushroom-derived cytotoxin, administered for five consecutive days every four weeks in patients with advanced solid malignancies.

1 reference

12 December 2020

Nonresponsiveness of the metastatic human lung carcinoma MV522 xenograft to conventional anticancer agents

1 reference

12 December 2020

Irofulven (6-hydroxymethylacylfulvene, MGI 114) induces caspase 8 and 9-mediated apoptosis in human pancreatic adenocarcinoma cells.

1 reference

12 December 2020

Use of nude mouse xenografts as preclinical drug screens: in vivo activity of established chemotherapeutic agents against melanoma and ovarian carcinoma xenografts.

1 reference

12 December 2020

Differential cytotoxicity and induction of apoptosis in tumor and normal cells by hydroxymethylacylfulvene (HMAF).

1 reference

12 December 2020

Potent inhibition of tumor survival in vivo by beta-lapachone plus taxol: combining drugs imposes different artificial checkpoints

1 reference

12 December 2020

Preclinical evaluation of illudins as anticancer agents.

1 reference

12 December 2020

Preclinical antitumor activity of 6-hydroxymethylacylfulvene, a semisynthetic derivative of the mushroom toxin illudin S.

1 reference

12 December 2020

Temporal relationship of CDK1 activation and mitotic arrest to cytosolic accumulation of cytochrome C and caspase-3 activity during Taxol-induced apoptosis of human AML HL-60 cells

1 reference

12 December 2020

Anti-leukemic action of the novel agent MGI 114 (HMAF) and synergistic action with topotecan

1 reference

12 December 2020

Drug uptake and cellular targets of hydroxymethylacylfulvene (HMAF)

1 reference

12 December 2020

Enhanced antitumor activity of irofulven in combination with thiotepa or mitomycin C.

1 reference

12 December 2020

Efficacy of MGI 114 (HMAF) against the MRP+ metastatic MV522 lung carcinoma xenograft.

1 reference

12 December 2020

Enhanced antitumour activity of 6-hydroxymethylacylfulvene in combination with topotecan or paclitaxel in the MV522 lung carcinoma xenograft model

1 reference

12 December 2020

Enhanced antitumor activity of 6-hydroxymethylacylfulvene in combination with irinotecan and 5-fluorouracil in the HT29 human colon tumor xenograft model

1 reference

12 December 2020

In vivo antitumour efficacy of MGI-114 (6-hydroxymethylacylfulvene, HMAF) in various human tumour xenograft models including several lung and gastric tumours

1 reference

12 December 2020

Efficacy of HMAF (MGI-114) in the MV522 metastatic lung carcinoma xenograft model nonresponsive to traditional anticancer agents

1 reference

12 December 2020

Efficacy of MGI 114 (6-hydroxymethylacylfulvene, HMAF) against the mdr1/gp170 metastatic MV522 lung carcinoma xenograft

1 reference

12 December 2020

Caspase-3 activation is not responsible for vinblastine-induced Bcl-2 phosphorylation and G2/M arrest in human small cell lung carcinoma Ms-1 cells.

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1016201807796

1 reference

Dimensions Publication ID

30 November 2017

1025675151

0 references

1 reference