(Q27318414)

English

The bile acid sensor FXR protects against dyslipidemia and aortic plaques development induced by the HIV protease inhibitor ritonavir in mice

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scholarly article

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The bile acid sensor FXR protects against dyslipidemia and aortic plaques development induced by the HIV protease inhibitor ritonavir in mice (English)

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1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Stefano Fiorucci

8

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Daniela Francisci

4

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author name string

Andrea Mencarelli

1

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Sabrina Cipriani

2

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Barbara Renga

3

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Giuseppe Palladino

5

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Eleonora Distrutti

6

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Franco Baldelli

7

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language of work or name

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publication date

2010

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5

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10

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e13238

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copyright license

Creative Commons Attribution 4.0 International

8 October 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Identification of a nuclear receptor for bile acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

21 March 2017

Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

21 March 2017

Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

21 March 2017

Inflammation in atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

7 April 2017

Bile acid-activated receptors in the treatment of dyslipidemia and related disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

28 September 2017

FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

28 September 2017

Activation of farnesoid X receptor prevents atherosclerotic lesion formation in LDLR-/- and apoE-/- mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

28 September 2017

Farnesoid x receptor ligands inhibit vascular smooth muscle cell inflammation and migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

28 September 2017

Molecular characterization of the role of orphan receptor small heterodimer partner in development of fatty liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

28 September 2017

A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

28 September 2017

Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

28 September 2017

Update on HAART in HIV.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

28 September 2017

HIV protease inhibitors activate the unfolded protein response in macrophages: implication for atherosclerosis and cardiovascular disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

28 September 2017

Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

28 September 2017

Endoplasmic reticulum stress links dyslipidemia to inhibition of proteasome activity and glucose transport by HIV protease inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

28 September 2017

ATP-binding cassette transporter AI and its role in HDL formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

28 September 2017

Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

28 September 2017

Expression and activation of the farnesoid X receptor in the vasculature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

28 September 2017

Atherosclerosis and HIV in the highly active antiretroviral therapy era: towards an epidemic of cardiovascular disease?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

28 September 2017

HIV protease inhibitors promote atherosclerotic lesion formation independent of dyslipidemia by increasing CD36-dependent cholesteryl ester accumulation in macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

28 September 2017

Innate and acquired immunity in atherogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

28 September 2017

Dual promoter structure of mouse and human fatty acid translocase/CD36 genes and unique transcriptional activation by peroxisome proliferator-activated receptor alpha and gamma ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

28 September 2017

Scavenger receptors, oxidized LDL, and atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

28 September 2017

Class A scavenger receptors, macrophages, and atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

28 September 2017

Hyperlipidemia and inhibitors of HIV protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

28 September 2017

Metabolic disorders among HIV-infected patients treated with protease inhibitors: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

28 September 2017

CD36 and atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

28 September 2017

Pathogenesis of HIV-1-protease inhibitor-associated peripheral lipodystrophy, hyperlipidaemia, and insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

31 May 2018

HIV-protease inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

31 May 2018

Chenodeoxycholic acid therapy for hypertriglyceridaemia in men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951893

31 May 2018

Reviewing the cardiovascular complications of HIV infection after the introduction of highly active antiretroviral therapy.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013238

21 January 2018

HIV protease inhibitor induces fatty acid and sterol biosynthesis in liver and adipose tissues due to the accumulation of activated sterol regulatory element-binding proteins in the nucleus

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013238

21 January 2018

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013238

21 January 2018

Antiatherosclerotic effect of farnesoid X receptor

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013238

21 January 2018

Loss of functional farnesoid X receptor increases atherosclerotic lesions in apolipoprotein E-deficient mice

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013238

21 January 2018

Class of Antiretroviral Drugs and the Risk of Myocardial Infarction

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013238

21 January 2018

HIV protease inhibitors stimulate hepatic triglyceride synthesis.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013238

21 January 2018

Redundant pathways for negative feedback regulation of bile acid production

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013238

21 January 2018

Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013238

21 January 2018

Gemfibrozil decreases atherosclerosis in experimental diabetes in association with a reduction in oxidative stress and inflammation

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013238

21 January 2018

Increased atherosclerosis following treatment with a dual PPAR agonist in the ApoE knockout mouse.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013238

21 January 2018

Cardiovascular Risks of Antiretroviral Therapy

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013238

21 January 2018

Coronary heart disease in HIV-infected individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triglyceride-lowering effect of chenodeoxycholic acid in patients with endogenous hypertriglyceridaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pregnane X receptor is a target of farnesoid X receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0013238

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2010PLoSO...513238M

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release_wuvh4nxtp5bw3pa6wpbkmz6u5u

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PMC publication ID

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PubMed publication ID

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ResearchGate publication ID

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