(Q27330384)

English

Natural product Celastrol destabilizes tubulin heterodimer and facilitates mitotic cell death triggered by microtubule-targeting anti-cancer drugs

scientific article (publication date: 2010)

In more languages

Statements

scholarly article

0 references

Natural product Celastrol destabilizes tubulin heterodimer and facilitates mitotic cell death triggered by microtubule-targeting anti-cancer drugs (English)

0 references

0 references

natural product

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Hakryul Jo

1

author given names

Hakryul

author last names

Jo

1 reference

20 October 2023

Fabien Loison

2

author given names

Fabien

author last names

Loison

1 reference

20 October 2023

Hidenori Hattori

3

author given names

Hidenori

author last names

Hattori

1 reference

20 October 2023

Leslie E Silberstein

4

author given names

Leslie E

author last names

Silberstein

1 reference

20 October 2023

Hongtao Yu

5

author given names

Hongtao

author last names

Yu

1 reference

20 October 2023

Hongbo R Luo

6

author given names

Hongbo R

author last names

Luo

1 reference

20 October 2023

language of work or name

0 references

publication date

2010

0 references

0 references

5

0 references

4

0 references

e10318

0 references

copyright license

Creative Commons Attribution 4.0 International

23 April 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Structure-function relationship of CAP-Gly domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

21 March 2017

Tubulin polyglutamylase enzymes are members of the TTL domain protein family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

21 March 2017

Stem-loop binding protein, the protein that binds the 3' end of histone mRNA, is cell cycle regulated by both translational and posttranslational mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

21 March 2017

A p34(cdc2) survival checkpoint in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

21 March 2017

Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

21 March 2017

Cyclin-dependent kinases: engines, clocks, and microprocessors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

7 April 2017

Intracellular beta-tubulin/chaperonin containing TCP1-beta complex serves as a novel chemotherapeutic target against drug-resistant tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

28 September 2017

Cancer preventive isothiocyanates induce selective degradation of cellular alpha- and beta-tubulins by proteasomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

28 September 2017

Discovery of ixabepilone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

28 September 2017

Ciliary tubulin and its post-translational modifications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

28 September 2017

Molecular dissection of the centrosome overduplication pathway in S-phase-arrested cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

28 September 2017

Capturing protein tails by CAP-Gly domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

28 September 2017

Covalent binding to tubulin by isothiocyanates. A mechanism of cell growth arrest and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

28 September 2017

Cancer cell-derived clusterin modulates the phosphatidylinositol 3'-kinase-Akt pathway through attenuation of insulin-like growth factor 1 during serum deprivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

28 September 2017

Inhibitory effects of parthenolide on antigen-induced microtubule formation and degranulation in mast cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

28 September 2017

Preclinical investigations with epothilones in breast cancer models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

28 September 2017

Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

28 September 2017

Tubulin modifications and their cellular functions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

28 September 2017

A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

28 September 2017

Strategies for the development of novel Taxol-like agents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

28 September 2017

Oncogenes and tumour suppressors take on centrosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

28 September 2017

Molecular understanding and modern application of traditional medicines: triumphs and trials.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

28 September 2017

Microtubule-organizing centres: a re-evaluation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

28 September 2017

Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-kappaB-regulated gene products and TAK1-mediated NF-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

28 September 2017

Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

28 September 2017

Deactivation of phosphatidylinositol 3,4,5-trisphosphate/Akt signaling mediates neutrophil spontaneous death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

28 September 2017

Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine," is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

28 September 2017

Antimitotic agents of natural origin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

28 September 2017

Requirement of Hsp90 for centrosomal function reflects its regulation of Polo kinase stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

28 September 2017

Interactions of tubulin and microtubule-associated proteins. Conformation and stability of the oligomeric species from glycerol-cycled microtubule protein of bovine brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

2 June 2018

Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

27 November 2018

Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

27 November 2018

PtdIns(3,4,5)P3 regulates spindle orientation in adherent cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

27 November 2018

The alpha- and beta-tubulin folding pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

27 November 2018

Sulfonamide drugs binding to the colchicine site of tubulin: thermodynamic analysis of the drug-tubulin interactions by isothermal titration calorimetry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

27 November 2018

Heat shock protein 90 regulates the metaphase-anaphase transition in a polo-like kinase-dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859055

27 November 2018

Parthenolide inhibits tubulin carboxypeptidase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20428237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence against tubulin oligomer dissociation to tubulin dimer at assembly temperatures

1 reference

https://pubmed.ncbi.nlm.nih.gov/20428237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiinflammatory constituents of Celastrus orbiculatus inhibit the NF-kappaB activation and NO production

1 reference

https://pubmed.ncbi.nlm.nih.gov/20428237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paclitaxel-induced apoptosis and mitotic arrest assessed by serial fine-needle aspiration: implications for early prediction of breast cancer response to neoadjuvant treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/20428237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship of mitotic arrest and apoptosis to antitumor effect of paclitaxel

1 reference

https://pubmed.ncbi.nlm.nih.gov/20428237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nondisulfide crosslinking and chemical cleavage of tubulin subunits: pH and temperature dependence

1 reference

https://pubmed.ncbi.nlm.nih.gov/20428237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of Tubulin by Vanadate Ion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20428237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphism of tubulin oligomers in the presence of microtubule-associated proteins. Implications in microtubule assembly

1 reference

https://pubmed.ncbi.nlm.nih.gov/20428237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0010318

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2010PLoSO...510318J

0 references

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

0 references

0 references

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q27330384&oldid=1993866438"