(Q27335488)

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Pharmacokinetic Modeling and Dose Selection in a Randomized, Double-Blind, Placebo-Controlled Trial of a Human Recombinant Alkaline Phosphatase in Healthy Volunteers

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scholarly article

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Europe PubMed Central

PubMed publication ID

26 June 2017

Pharmacokinetic Modeling and Dose Selection in a Randomized, Double-Blind, Placebo-Controlled Trial of a Human Recombinant Alkaline Phosphatase in Healthy Volunteers (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

0 references

pharmacokinetics

1 reference

based on heuristic

inferred from title

placebo-controlled trial

1 reference

based on heuristic

inferred from title

Jules Heuberger

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27147514%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Rosalinde Masereeuw

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27147514%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

7

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27147514%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

8

object named as

Peter Pickkers

1 reference

Europe PubMed Central

PMC publication ID

5 June 2020

author name string

Esther Peters

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27147514%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Renger Tiessen

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27147514%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Andrea van Elsas

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27147514%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Jacques Arend

6

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27147514%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

language of work or name

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publication date

4 May 2016

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

Clinical Pharmacokinetics

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27147514%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

55

1 reference

Europe PubMed Central

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5 June 2020

10

1 reference

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5 June 2020

1227-1237

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27147514%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

copyright license

Creative Commons Attribution-NonCommercial 4.0 International

4 May 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Biodistribution and translational pharmacokinetic modeling of a human recombinant alkaline phosphatase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021756

29 September 2017

Alkaline phosphatase protects against renal inflammation through dephosphorylation of lipopolysaccharide and adenosine triphosphate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021756

29 September 2017

Catalytic signature of a heat-stable, chimeric human alkaline phosphatase with therapeutic potential.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021756

29 September 2017

A unified theory of sepsis-induced acute kidney injury: inflammation, microcirculatory dysfunction, bioenergetics, and the tubular cell adaptation to injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021756

29 September 2017

Acute kidney injury: an increasing global concern

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021756

29 September 2017

Epidemiology of acute kidney injury in the intensive care unit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021756

29 September 2017

Alkaline phosphatase for treatment of sepsis-induced acute kidney injury: a prospective randomized double-blind placebo-controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021756

29 September 2017

The severity of acute kidney injury predicts progression to chronic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021756

29 September 2017

Alkaline Phosphatases : Structure, substrate specificity and functional relatedness to other members of a large superfamily of enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021756

29 September 2017

Removal of phosphate from lipid A as a strategy to detoxify lipopolysaccharide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021756

29 September 2017

Importance of shrinkage in empirical bayes estimates for diagnostics: problems and solutions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021756

2 June 2018

Acute renal failure in patients with severe sepsis and septic shock--a significant independent risk factor for mortality: results from the German Prevalence Study

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0399-Y

21 January 2018

Ecto 5'-nucleotidase and nonspecific alkaline phosphatase. Two AMP-hydrolyzing ectoenzymes with distinct roles in human airways

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0399-Y

21 January 2018

Calf intestinal alkaline phosphatase, a novel therapeutic drug for lipopolysaccharide (LPS)-mediated diseases, attenuates LPS toxicity in mice and piglets

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0399-Y

21 January 2018

Beneficial effects of alkaline phosphatase in septic shock.

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0399-Y

21 January 2018

Reporting Guidelines for Clinical Pharmacokinetic Studies: The ClinPK Statement

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0399-Y

21 January 2018

Clinical pharmacology of exogenously administered alkaline phosphatase

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0399-Y

21 January 2018

Alkaline phosphatase treatment improves renal function in severe sepsis or septic shock patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021756

27 November 2018

Identifiers

10.1007/S40262-016-0399-Y

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27147514%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Dimensions Publication ID

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release_gkgnriapijgbzin6wjkmfof2ee

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27147514%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27147514%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

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