(Q27335766)

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Mammalian target of rapamycin is a therapeutic target for murine ovarian endometrioid adenocarcinomas with dysregulated Wnt/β-catenin and PTEN

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Mammalian target of rapamycin is a therapeutic target for murine ovarian endometrioid adenocarcinomas with dysregulated Wnt/β-catenin and PTEN (English)

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1 reference

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inferred from title

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Tomoko Kaneko-Tarui

object named as

Tomoko Kaneko-Tarui

3

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Jose M Teixeira

object named as

Jose M Teixeira

8

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author name string

Pradeep S Tanwar

1

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LiHua Zhang

2

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Michael D Curley

4

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Makoto M Taketo

5

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Poonam Rani

6

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Drucilla J Roberts

7

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language of work or name

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publication date

2011

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6

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6

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e20715

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copyright license

Creative Commons Attribution 4.0 International

9 June 2011

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April 2022 Public Data File from Crossref

copyright status

0 references

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1 reference

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21 March 2017

Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

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21 March 2017

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1 reference

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21 March 2017

PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

1 reference

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21 March 2017

Formation of ovarian follicles during fetal development in sheep

1 reference

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21 March 2017

Ovarian surface epithelium: biology, endocrinology, and pathology

1 reference

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21 March 2017

Upstream and downstream of mTOR

1 reference

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21 March 2017

Requirement of Bmpr1a for Müllerian duct regression during male sexual development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

21 March 2017

Tumorigenesis in the multiple intestinal neoplasia mouse: redundancy of negative regulators and specificity of modifiers

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21 March 2017

Female development in mammals is regulated by Wnt-4 signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

21 March 2017

mTOR and cancer: insights into a complex relationship

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

7 April 2017

Smad1-Smad5 ovarian conditional knockout mice develop a disease profile similar to the juvenile form of human granulosa cell tumors

1 reference

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24 May 2017

β-Catenin activation synergizes with PTEN loss to cause bladder cancer formation.

1 reference

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29 September 2017

Beta-catenin (CTNNB1) promotes preovulatory follicular development but represses LH-mediated ovulation and luteinization

1 reference

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29 September 2017

Ovarian cancer pathogenesis: a model in evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

29 September 2017

mTOR is a promising therapeutic target both in cisplatin-sensitive and cisplatin-resistant clear cell carcinoma of the ovary

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

29 September 2017

Cell type-specific targeted mutations of Kras and Pten document proliferation arrest in granulosa cells versus oncogenic insult to ovarian surface epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

29 September 2017

Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

29 September 2017

The biology of ovarian cancer: new opportunities for translation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

29 September 2017

Constitutive activation of Beta-catenin in uterine stroma and smooth muscle leads to the development of mesenchymal tumors in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

29 September 2017

Serum Müllerian Inhibiting Substance/anti-Müllerian hormone levels in patients with adult granulosa cell tumors directly correlate with aggregate tumor mass as determined by pathology or radiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

29 September 2017

Ovarian cancer: pathology, biology, and disease models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

29 September 2017

Expression of activated PIK3CA in ovarian surface epithelium results in hyperplasia but not tumor formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

29 September 2017

Inhibition of the mTORC1 pathway suppresses intestinal polyp formation and reduces mortality in ApcDelta716 mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

29 September 2017

Normal ovarian surface epithelial label-retaining cells exhibit stem/progenitor cell characteristics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

29 September 2017

Synergistic effects of Pten loss and WNT/CTNNB1 signaling pathway activation in ovarian granulosa cell tumor development and progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

29 September 2017

Targeted disruption of Pten in ovarian granulosa cells enhances ovulation and extends the life span of luteal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

29 September 2017

Wnt signaling in ovarian tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

29 September 2017

c-Jun N-terminal kinase inhibitor II (SP600125) activates Mullerian inhibiting substance type II receptor-mediated signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

29 September 2017

Cellular senescence in cancer and aging

1 reference

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Adult mouse myometrial label-retaining cells divide in response to gonadotropin stimulation

1 reference

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29 September 2017

Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsiveness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

29 September 2017

Origins and molecular pathology of ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

29 September 2017

Developmental genetics of the female reproductive tract in mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

29 September 2017

Induction of ovarian cancer by defined multiple genetic changes in a mouse model system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

29 September 2017

The invasion front of human colorectal adenocarcinomas shows co-localization of nuclear beta-catenin, cyclin D1, and p16INK4A and is a region of low proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

29 September 2017

Müllerian inhibiting substance: an instructive developmental hormone with diagnostic and possible therapeutic applications

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

29 September 2017

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27 November 2018

Deregulated beta-catenin induces a p53- and ARF-dependent growth arrest and cooperates with Ras in transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

29 September 2017

Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment

1 reference

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29 September 2017

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

29 September 2017

Mammalian target of rapamycin-dependent acinar cell neoplasia after inactivation of Apc and Pten in the mouse salivary gland: implications for human acinic cell carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

2 June 2018

Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

2 June 2018

Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0020715

21 January 2018

Antitumor activity of rapamycin in a transgenic mouse model of ErbB2-dependent human breast cancer

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0020715

21 January 2018

A mesenchymal perspective of Müllerian duct differentiation and regression in Amhr2-lacZ mice.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0020715

21 January 2018

Expression of anti-Müllerian hormone (AMH) in equine granulosa-cell tumors and in normal equine ovaries

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0020715

21 January 2018

APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0020715

21 January 2018

Misregulated Wnt/beta-catenin signaling leads to ovarian granulosa cell tumor development.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0020715

21 January 2018

RAD001 (Everolimus) delays tumor onset and progression in a transgenic mouse model of ovarian cancer.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0020715

21 January 2018

Female mice chimeric for expression of the simian virus 40 TAg under control of the MISIIR promoter develop epithelial ovarian cancer.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

27 November 2018

Lack of tumorigenesis in the mouse liver after adenovirus-mediated expression of a dominant stable mutant of beta-catenin.

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27 November 2018

Diverse mechanisms of beta-catenin deregulation in ovarian endometrioid adenocarcinomas.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111436

27 November 2018

Conditional deletion of beta-catenin in the mesenchyme of the developing mouse uterus results in a switch to adipogenesis in the myometrium

1 reference

https://pubmed.ncbi.nlm.nih.gov/21695255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-catenin mutation and expression analysis in ovarian cancer: exon 3 mutations and nuclear translocation in 16% of endometrioid tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/21695255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lineage infidelity of epithelial ovarian cancers is controlled by HOX genes that specify regional identity in the reproductive tract

1 reference

https://pubmed.ncbi.nlm.nih.gov/21695255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulated expression of Wnts and Frizzleds at specific stages of follicular development in the rodent ovary

1 reference

https://pubmed.ncbi.nlm.nih.gov/21695255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0020715

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2011PLoSO...620715T

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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