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Drosophila Xpd regulates Cdk7 localization, mitotic kinase activity, spindle dynamics, and chromosome segregation
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PMC publication ID
2837399
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21 January 2020
title
Drosophila Xpd regulates Cdk7 localization, mitotic kinase activity, spindle dynamics, and chromosome segregation
(English)
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PMC publication ID
2837399
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21 January 2020
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Drosophila
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Xeroderma pigmentosum D Dmel_CG9433
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GOA release 2020-03-11
author
Olivier Urwyler
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2
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2837399
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21 January 2020
author name string
Xiaoming Li
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1
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2837399
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21 January 2020
Beat Suter
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3
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2837399
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21 January 2020
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English
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12 March 2010
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2837399
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21 January 2020
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PLOS Genetics
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PMC publication ID
2837399
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21 January 2020
volume
6
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2837399
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21 January 2020
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3
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2837399
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21 January 2020
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e1000876
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2837399
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21 January 2020
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Creative Commons Attribution 4.0 International
start time
12 March 2010
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11 June 2022
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DNA repair and transcriptional deficiencies caused by mutations in the Drosophila p52 subunit of TFIIH generate developmental defects and chromosome fragility.
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Drosophila Wee1 interacts with members of the gammaTURC and is required for proper mitotic-spindle morphogenesis and positioning
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cdk-7 Is required for mRNA transcription and cell cycle progression in Caenorhabditis elegans embryos
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T-loop phosphorylation stabilizes the CDK7-cyclin H-MAT1 complex in vivo and regulates its CTD kinase activity
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Exit from mitosis in Drosophila syncytial embryos requires proteolysis and cyclin degradation, and is associated with localized dephosphorylation
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Cdk7 is essential for mitosis and for in vivo Cdk-activating kinase activity.
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Regulation of CDK7 substrate specificity by MAT1 and TFIIH.
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29 September 2017
Synergistic action of Drosophila cyclins A and B during the G2-M transition
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cdc2 phosphorylation is required for its interaction with cyclin.
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TFIIH controls developmentally-regulated cell cycle progression as a holocomplex
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Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics
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2 June 2018
Gal4 in the Drosophila female germline
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2 June 2018
The Drosophila homeotic target gene centrosomin (cnn) encodes a novel centrosomal protein with leucine zippers and maps to a genomic region required for midgut morphogenesis
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2 June 2018
The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor
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2 June 2018
Flies without a spindle checkpoint
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27 November 2018
TFIIH trafficking and its nuclear assembly during early Drosophila embryo development.
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27 November 2018
Maternal expression of the checkpoint protein BubR1 is required for synchrony of syncytial nuclear divisions and polar body arrest in Drosophila melanogaster
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27 November 2018
Xpd/Ercc2 regulates CAK activity and mitotic progression
1 reference
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PubMed Central
reference URL
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27 November 2018
Drosophila checkpoint kinase 2 couples centrosome function and spindle assembly to genomic integrity
1 reference
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27 November 2018
The roles of Fzy/Cdc20 and Fzr/Cdh1 in regulating the destruction of cyclin B in space and time
1 reference
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27 November 2018
Cyclin A and B functions in the early Drosophila embryo.
1 reference
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837399
retrieved
27 November 2018
Distinct molecular mechanism regulate cell cycle timing at successive stages of Drosophila embryogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837399
retrieved
27 November 2018
DNA-replication/DNA-damage-dependent centrosome inactivation in Drosophila embryos
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/20300654
retrieved
12 December 2020
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DOI
10.1371/JOURNAL.PGEN.1000876
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Europe PubMed Central
PMC publication ID
2837399
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20300654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
PMC publication ID
2837399
1 reference
stated in
Europe PubMed Central
PMC publication ID
2837399
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20300654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
PubMed publication ID
20300654
1 reference
stated in
Europe PubMed Central
PMC publication ID
2837399
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20300654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
ResearchGate publication ID
42346202
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