(Q29811781)

RAD3/XPD family

1 reference

ATP-dependent helicase, C-terminal domain, protein family

1 reference

Helical and beta-bridge domain, protein family

1 reference

DEAD2, protein family

1 reference

Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type, protein family

1 reference

Helicase-like, DEXD box c2 type, protein family

1 reference

DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, protein family

1 reference

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

1 reference

8 April 2019

nucleic acid binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

1 reference

8 April 2019

DNA binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

1 reference

8 April 2019

DNA helicase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KVP9&geneProductId=UniProtKB:Q7KVP9

1 reference

16 July 2018

hydrolase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

1 reference

8 April 2019

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

1 reference

8 April 2019

5'-3' DNA helicase activity

1 reference

16 July 2018

The Drosophila melanogaster homologue of the Xeroderma pigmentosum D gene product is located in euchromatic regions and has a dynamic response to UV light-induced lesions in polytene chromosomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KVP9&geneProductId=UniProtKB:Q7KVP9

damaged DNA binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

RNA polymerase II CTD heptapeptide repeat kinase activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

5'-3' DNA helicase activity

transcription factor TFIIH core complex

cell component

The Drosophila melanogaster homologue of the Xeroderma pigmentosum D gene product is located in euchromatic regions and has a dynamic response to UV light-induced lesions in polytene chromosomes

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

8 April 2019

p8/TTDA overexpression enhances UV-irradiation resistance and suppresses TFIIH mutations in a Drosophila trichothiodystrophy model

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KVP9&geneProductId=UniProtKB:Q7KVP9

5 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KVP9&geneProductId=UniProtKB:Q7KVP9

16 July 2018

16 July 2018

The Drosophila melanogaster homologue of the Xeroderma pigmentosum D gene product is located in euchromatic regions and has a dynamic response to UV light-induced lesions in polytene chromosomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KVP9&geneProductId=UniProtKB:Q7KVP9

16 July 2018

p8/TTDA overexpression enhances UV-irradiation resistance and suppresses TFIIH mutations in a Drosophila trichothiodystrophy model

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KVP9&geneProductId=UniProtKB:Q7KVP9

16 July 2018

DNA repair and transcriptional deficiencies caused by mutations in the Drosophila p52 subunit of TFIIH generate developmental defects and chromosome fragility.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KVP9&geneProductId=UniProtKB:Q7KVP9

transcription factor TFIIH holo complex

The Drosophila melanogaster homologue of the Xeroderma pigmentosum D gene product is located in euchromatic regions and has a dynamic response to UV light-induced lesions in polytene chromosomes

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

8 April 2019

Genes encoding Drosophila melanogaster RNA polymerase II general transcription factors: diversity in TFIIA and TFIID components contributes to gene-specific transcriptional regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

8 April 2019

A Drosophila XPD model links cell cycle coordination with neuro-development and suggests links to cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

IPI

polytene chromosome

1 reference

8 April 2019

Physical and functional interactions between Drosophila homologue of Swc6/p18Hamlet subunit of the SWR1/SRCAP chromatin-remodeling complex with the DNA repair/transcription factor TFIIH.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

polytene chromosome puff

1 reference

8 April 2019

The Drosophila melanogaster homologue of the Xeroderma pigmentosum D gene product is located in euchromatic regions and has a dynamic response to UV light-induced lesions in polytene chromosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

polytene chromosome interband

1 reference

8 April 2019

The Drosophila melanogaster homologue of the Xeroderma pigmentosum D gene product is located in euchromatic regions and has a dynamic response to UV light-induced lesions in polytene chromosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

cytoplasm

1 reference

8 April 2019

The Drosophila melanogaster homologue of the Xeroderma pigmentosum D gene product is located in euchromatic regions and has a dynamic response to UV light-induced lesions in polytene chromosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

8 April 2019

8 April 2019

p8/TTDA overexpression enhances UV-irradiation resistance and suppresses TFIIH mutations in a Drosophila trichothiodystrophy model

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

8 April 2019

DNA repair and transcriptional deficiencies caused by mutations in the Drosophila p52 subunit of TFIIH generate developmental defects and chromosome fragility.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

8 April 2019

The Drosophila melanogaster homologue of the Xeroderma pigmentosum D gene product is located in euchromatic regions and has a dynamic response to UV light-induced lesions in polytene chromosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

promoter clearance from RNA polymerase II promoter

biological process

1 reference

8 April 2019

The Drosophila melanogaster homologue of the Xeroderma pigmentosum D gene product is located in euchromatic regions and has a dynamic response to UV light-induced lesions in polytene chromosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

transcription open complex formation at RNA polymerase II promoter

1 reference

8 April 2019

The Drosophila melanogaster homologue of the Xeroderma pigmentosum D gene product is located in euchromatic regions and has a dynamic response to UV light-induced lesions in polytene chromosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

nucleobase-containing compound metabolic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

1 reference

8 April 2019

transcription initiation from RNA polymerase II promoter

1 reference

8 April 2019

Genes encoding Drosophila melanogaster RNA polymerase II general transcription factors: diversity in TFIIA and TFIID components contributes to gene-specific transcriptional regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

cellular response to DNA damage stimulus

1 reference

8 April 2019

The Drosophila melanogaster homologue of the Xeroderma pigmentosum D gene product is located in euchromatic regions and has a dynamic response to UV light-induced lesions in polytene chromosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

regulation of mitotic nuclear division

1 reference

8 April 2019

Xpd/Ercc2 regulates CAK activity and mitotic progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

regulation of syncytial blastoderm mitotic cell cycle

1 reference

8 April 2019

A Drosophila XPD model links cell cycle coordination with neuro-development and suggests links to cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

response to UV

A Drosophila XPD model links cell cycle coordination with neuro-development and suggests links to cancer

3 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KVP9&geneProductId=UniProtKB:Q7KVP9

16 July 2018

The Drosophila melanogaster homologue of the Xeroderma pigmentosum D gene product is located in euchromatic regions and has a dynamic response to UV light-induced lesions in polytene chromosomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KVP9&geneProductId=UniProtKB:Q7KVP9

16 July 2018

Increased UV light sensitivity in transgenic Drosophila expressing the antisense XPD homolog

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KVP9&geneProductId=UniProtKB:Q7KVP9

negative regulation of G2/M transition of mitotic cell cycle

1 reference

8 April 2019

Xpd/Ercc2 regulates CAK activity and mitotic progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

DNA duplex unwinding

1 reference

16 July 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KVP9&geneProductId=UniProtKB:Q7KVP9

regulation of chromosome segregation

1 reference

8 April 2019

Drosophila Xpd regulates Cdk7 localization, mitotic kinase activity, spindle dynamics, and chromosome segregation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

regulation of nucleic acid-templated transcription

1 reference

16 July 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KVP9&geneProductId=UniProtKB:Q7KVP9

regulation of mitotic recombination

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

nucleotide-excision repair, DNA duplex unwinding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

transcription by RNA polymerase II

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

protein phosphorylation

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

response to oxidative stress

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

response to UV

A Drosophila XPD model links cell cycle coordination with neuro-development and suggests links to cancer

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

8 April 2019

The Drosophila melanogaster homologue of the Xeroderma pigmentosum D gene product is located in euchromatic regions and has a dynamic response to UV light-induced lesions in polytene chromosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

8 April 2019

Increased UV light sensitivity in transgenic Drosophila expressing the antisense XPD homolog

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

nucleotide-excision repair, DNA incision

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

positive regulation of transcription, DNA-templated

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

positive regulation of mitotic recombination

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KVP9

1 reference

Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type

1 reference

DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site

1 reference

ATP-dependent helicase, C-terminal

1 reference

Helical and beta-bridge domain

1 reference

Helicase-like, DEXD box c2 type

1 reference