(Q27437610)

English

Megalin/LRP2 expression is induced by peroxisome proliferator-activated receptor -alpha and -gamma: implications for PPARs' roles in renal function

scientific article (publication date: 2011)

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scholarly article

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Megalin/LRP2 expression is induced by peroxisome proliferator-activated receptor -alpha and -gamma: implications for PPARs' roles in renal function (English)

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object named as

Carlos P Vio

4

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author name string

Felipe Cabezas

1

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Jonathan Lagos

2

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Carlos Céspedes

3

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Miguel Bronfman

5

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María-Paz Marzolo

6

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publication date

2011

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6

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2

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e16794

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Creative Commons Attribution 4.0 International

2 February 2011

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April 2022 Public Data File from Crossref

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Comparative analysis of gene regulation by the transcription factor PPARalpha between mouse and human

1 reference

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1 reference

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Mutations in LRP2, which encodes the multiligand receptor megalin, cause Donnai-Barrow and facio-oculo-acoustico-renal syndromes

1 reference

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1 reference

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1 reference

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Defective forebrain development in mice lacking gp330/megalin

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Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat

1 reference

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Endocytosis of megalin by visceral endoderm cells requires the Dab2 adaptor protein

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LRP2/megalin is required for patterning of the ventral telencephalon

1 reference

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Age-related change of endocytic receptors megalin and cubilin in the kidney in rats

1 reference

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Expression of peroxisome proliferator-activated receptors (PPARs) and retinoic acid receptors (RXRs) in rat cortical neurons

1 reference

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Evidence indicating that renal tubular metabolism of leptin is mediated by megalin but not by the leptin receptors

1 reference

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Regulation of gp330/megalin expression by vitamins A and D

1 reference

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21 March 2017

PPAR-gamma agonist rosiglitazone reverses increased cerebral venous hydraulic conductivity during hypertension

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Metallothionein-I+II in neuroprotection

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29 September 2017

Antifibrotic effects of pioglitazone on the kidney in a rat model of type 2 diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Regulation of megalin expression in cultured proximal tubule cells by angiotensin II type 1A receptor- and insulin-mediated signaling cross talk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Peroxisome proliferator-activated receptor alpha activation attenuated angiotensin type 1-mediated but enhanced angiotensin type 2-mediated hemodynamic effects to angiotensin II in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Metallothionein and a peptide modeled after metallothionein, EmtinB, induce neuronal differentiation and survival through binding to receptors of the low-density lipoprotein receptor family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

The PPAR alpha-humanized mouse: a model to investigate species differences in liver toxicity mediated by PPAR alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Leptin is a coactivator of TGF-beta in unilateral ureteral obstructive kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Mechanisms of disease: what can mouse models tell us about the molecular processes underlying Dent disease?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

A cytoplasmic PPPSP motif determines megalin's phosphorylation and regulates receptor's recycling and surface expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Cytotoxicity of peroxisome proliferator-activated receptor alpha and gamma agonists in renal proximal tubular cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Megalin mediates the transport of leptin across the blood-CSF barrier.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

PKB and megalin determine the survival or death of renal proximal tubule cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Renal injury due to renin-angiotensin-aldosterone system activation of the transforming growth factor-beta pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Leptin and renal fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Megalin binds and internalizes angiotensin-(1-7).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Effect of peroxisome proliferator-activated receptor-gamma ligand on inflammation of human gallbladder epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Pleiotropic effects of fibrates

1 reference

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29 September 2017

Activation of mitogen-activated protein kinases by peroxisome proliferator-activated receptor ligands: an example of nongenomic signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Evidence for megalin-mediated proximal tubular uptake of L-FABP, a carrier of potentially nephrotoxic molecules.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Peroxisome proliferator-activated receptor family and its relationship to renal complications of the metabolic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Megalin binds and internalizes angiotensin II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Megalin and cubilin expression in gallbladder epithelium and regulation by bile acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Differential distribution of low-density lipoprotein-receptor-related protein (LRP) and megalin in polarized epithelial cells is determined by their cytoplasmic domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Megalin and the neurodevelopmental biology of sonic hedgehog and retinol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Adipocyte low density lipoprotein receptor-related protein gene expression and function is regulated by peroxisome proliferator-activated receptor gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Megalin and cubilin, role in proximal tubule function and during development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Lipoprotein receptors in the nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Megalin in thyroid physiology and pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Effects of peroxisome proliferator-activated receptor-alpha and -gamma agonist, JTT-501, on diabetic complications in Zucker diabetic fatty rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Megalin knockout mice as an animal model of low molecular weight proteinuria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Characterization of the human Megalin/LRP-2 promoter in vitro and in primary parathyroid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Peroxisome proliferators activate extracellular signal-regulated kinases in immortalized mouse liver cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Megalin/gp330 mediates uptake of albumin in renal proximal tubule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Interstitial nephritis induced by protein-overload proteinuria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

29 September 2017

Nebivolol attenuates maladaptive proximal tubule remodeling in transgenic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

2 June 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

2 June 2018

Ligand-independent activation of peroxisome proliferator-activated receptor-gamma by insulin and C-peptide in kidney proximal tubular cells: dependent on phosphatidylinositol 3-kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

2 June 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

2 June 2018

Megalin-mediated endocytosis in renal proximal tubule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

2 June 2018

Expression of peroxisome proliferator-activated receptors in urinary tract of rabbits and humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

2 June 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

2 June 2018

The expression of megalin (gp330) and LRP diverges during F9 cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

2 June 2018

Decreased renal uptake of (99m)Tc-DMSA in patients with tubular proteinuria.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

Transthyretin internalization by sensory neurons is megalin mediated and necessary for its neuritogenic activity.

1 reference

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21 January 2018

Cell division and phenotypic regression of proximal tubular cells in response to uranyl acetate insult in rats.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

Reduced albumin reabsorption in the proximal tubule of early-stage diabetic rats

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

Angiotensin II blockade restores albumin reabsorption in the proximal tubules of diabetic rats

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

Pioglitazone increases renal tubular cell albumin uptake but limits proinflammatory and fibrotic responses

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

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1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

PPAR-alpha and -gamma agonists attenuate diabetic kidney disease in the apolipoprotein E knockout mouse.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

PPARalpha agonist fenofibrate improves diabetic nephropathy in db/db mice.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

Pioglitazone reduces urinary podocyte excretion in type 2 diabetes patients with microalbuminuria

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

Comparative effects of pioglitazone, glibenclamide, and voglibose on urinary endothelin-1 and albumin excretion in diabetes patients

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

Rosiglitazone decreases albuminuria in type 2 diabetic patients.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

Effect of troglitazone on microalbuminuria in patients with incipient diabetic nephropathy.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

Peroxisome proliferator-activated receptor beta/delta exerts a strong protection from ischemic acute renal failure

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

Modulation of renal kallikrein by a high potassium diet in rats with intense proteinuria

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

Accelerated diabetic nephropathy in mice lacking the peroxisome proliferator-activated receptor alpha.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

Regulation of human hepatic hydroxysteroid sulfotransferase gene expression by the peroxisome proliferator-activated receptor alpha transcription factor

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

Fibrates down-regulate hepatic scavenger receptor class B type I protein expression in mice.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

PPAR-alpha activation protects the type 2 diabetic myocardium against ischemia-reperfusion injury: involvement of the PI3-Kinase/Akt and NO pathway

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

Linking receptor-mediated endocytosis and cell signaling: evidence for regulated intramembrane proteolysis of megalin in proximal tubule

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

Effect of pioglitazone on urinary liver-type fatty acid-binding protein concentrations in diabetes patients with microalbuminuria

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

Peroxisome-proliferator-activated receptor-alpha activation protects brain capillary endothelial cells from oxygen-glucose deprivation-induced hyperpermeability in the blood-brain barrier.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

Peroxisome proliferator-activated receptor gamma is expressed in hippocampal neurons and its activation prevents beta-amyloid neurodegeneration: role of Wnt signaling.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

Pregnant rats treated with a serotonin precursor have reduced fetal weight and lower plasma volume and kallikrein levels

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

CLA-1/SR-BI Is Expressed in Atherosclerotic Lesion Macrophages and Regulated by Activators of Peroxisome Proliferator-Activated Receptors

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

Megalin and proximal renal tubular dysfunction in Dent disease

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016794

21 January 2018

Renal phenotype of low kallikrein rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032793

27 November 2018

Proteinuria induces tubular cell turnover: A potential mechanism for tubular atrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21311715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Choroid Plexus Megalin Is Involved in Neuroprotection by Serum Insulin-Like Growth Factor I

1 reference

https://pubmed.ncbi.nlm.nih.gov/21311715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiotensin II activates the Smad pathway during epithelial mesenchymal transdifferentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21311715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipocalin-2-induced renal regeneration depends on cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/21311715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevalence of abnormal serum vitamin D, PTH, calcium, and phosphorus in patients with chronic kidney disease: results of the study to evaluate early kidney disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21311715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of peroxisome proliferator-activated receptor-alpha prevents glycogen synthase 3beta phosphorylation and inhibits cardiac hypertrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21311715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0016794

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Consolidated OpenCitations Corpus – April 2017

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2011PLoSO...616794C

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release_jwdjfcee65amlm7iv66isxc2lu

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OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

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