(Q27469831)

English

Chimeric Dengue 2 PDK-53/West Nile NY99 Viruses Retain the Phenotypic Attenuation Markers of the Candidate PDK-53 Vaccine Virus and Protect Mice against Lethal Challenge with West Nile Virus

scientific article (publication date: June 2005)

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scholarly article

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Chimeric Dengue 2 PDK-53/West Nile NY99 Viruses Retain the Phenotypic Attenuation Markers of the Candidate PDK-53 Vaccine Virus and Protect Mice against Lethal Challenge with West Nile Virus (English)

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West Nile virus

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author name string

Claire Y-H Huang

1

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Shawn J Silengo

2

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Melissa C Whiteman

3

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Richard M Kinney

4

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publication date

June 2005

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Journal of Virology

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79

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12

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7300-10

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Molecular biology of flaviviruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143654

21 March 2017

Dengue 2 PDK-53 Virus as a Chimeric Carrier for Tetravalent Dengue Vaccine Development

1 reference

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21 March 2017

Yellow Fever Virus/Dengue-2 Virus and Yellow Fever Virus/Dengue-4 Virus Chimeras: Biological Characterization, Immunogenicity, and Protection against Dengue Encephalitis in the Mouse Model

1 reference

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21 March 2017

West Nile virus/dengue type 4 virus chimeras that are reduced in neurovirulence and peripheral virulence without loss of immunogenicity or protective efficacy

1 reference

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21 March 2017

Molecular basis for attenuation of neurovirulence of a yellow fever Virus/Japanese encephalitis virus chimera vaccine (ChimeriVax-JE).

1 reference

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21 March 2017

Chimeric dengue type 2 (vaccine strain PDK-53)/dengue type 1 virus as a potential candidate dengue type 1 virus vaccine

1 reference

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21 March 2017

Attenuation markers of a candidate dengue type 2 vaccine virus, strain 16681 (PDK-53), are defined by mutations in the 5' noncoding region and nonstructural proteins 1 and 3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143654

21 March 2017

Mutagenesis of the signal sequence of yellow fever virus prM protein: enhancement of signalase cleavage In vitro is lethal for virus production

1 reference

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21 March 2017

Mutagenesis of the NS2B-NS3-mediated cleavage site in the flavivirus capsid protein demonstrates a requirement for coordinated processing

1 reference

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21 March 2017

Signal peptidase cleavage at the flavivirus C-prM junction: dependence on the viral NS2B-3 protease for efficient processing requires determinants in C, the signal peptide, and prM

1 reference

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21 March 2017

Attenuation of the Langat tick-borne flavivirus by chimerization with mosquito-borne flavivirus dengue type 4

1 reference

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21 March 2017

Monkeys immunized with intertypic chimeric dengue viruses are protected against wild-type virus challenge

1 reference

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21 March 2017

Genetic determinants of dengue type 4 virus neurovirulence for mice

1 reference

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21 March 2017

Chimeric tick-borne encephalitis and dengue type 4 viruses: effects of mutations on neurovirulence in mice

1 reference

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21 March 2017

NS2B-3 proteinase-mediated processing in the yellow fever virus structural region: in vitro and in vivo studies

1 reference

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21 March 2017

Observations related to the pathogenesis of dengue hemorrhagic fever. II. Antigenic and biologic properties of dengue viruses and their association with disease response in the host

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143654

21 March 2017

Immunization with a live attenuated dengue-2-virus candidate vaccine (16681-PDK 53): clinical, immunological and biological responses in adult volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143654

21 March 2017

Origin of the West Nile virus responsible for an outbreak of encephalitis in the northeastern United States

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143654

21 March 2017

Chimeric flaviviruses: novel vaccines against dengue fever, tick-borne encephalitis, and Japanese encephalitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143654

21 March 2017

ChimeriVax-West Nile virus live-attenuated vaccine: preclinical evaluation of safety, immunogenicity, and efficacy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143654

29 September 2017

Flavivirus encephalitis.

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29 September 2017

West Nile virus: a growing concern?

1 reference

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29 September 2017

Safety and efficacy of chimeric yellow Fever-dengue virus tetravalent vaccine formulations in nonhuman primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143654

29 September 2017

The epidemic of West Nile virus in the United States, 2002.

1 reference

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29 September 2017

Analysis of the replication kinetics of the ChimeriVax-DEN 1, 2, 3, 4 tetravalent virus mixture in Aedes aegypti by real-time reverse transcriptase-polymerase chain reaction.

1 reference

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29 September 2017

Molecular determinants of virulence: the structural and functional basis for flavivirus attenuation

1 reference

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29 September 2017

Inefficient signalase cleavage promotes efficient nucleocapsid incorporation into budding flavivirus membranes

1 reference

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29 September 2017

Chimeric live, attenuated vaccine against Japanese encephalitis (ChimeriVax-JE): phase 2 clinical trials for safety and immunogenicity, effect of vaccine dose and schedule, and memory response to challenge with inactivated Japanese encephalitis anti

1 reference

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29 September 2017

Molecularly engineered live-attenuated chimeric West Nile/dengue virus vaccines protect rhesus monkeys from West Nile virus

1 reference

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29 September 2017

Chimeric dengue type 2/type 1 viruses induce immune responses in cynomolgus monkeys

1 reference

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29 September 2017

Growth characteristics of ChimeriVax-DEN2 vaccine virus in Aedes aegypti and Aedes albopictus mosquitoes

1 reference

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Safety and immunogenicity of tetravalent live-attenuated dengue vaccines in Thai adult volunteers: role of serotype concentration, ratio, and multiple doses.

1 reference

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29 September 2017

A live attenuated recombinant dengue-4 virus vaccine candidate with restricted capacity for dissemination in mosquitoes and lack of transmission from vaccinees to mosquitoes.

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29 September 2017

West Nile encephalitis: an emerging disease in the United States

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29 September 2017

Yellow fever vector live-virus vaccines: West Nile virus vaccine development

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Development of new vaccines against dengue fever and Japanese encephalitis

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Safety and immunogenicity of attenuated dengue virus vaccines (Aventis Pasteur) in human volunteers

1 reference

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Infectious cDNA clone of attenuated Langat tick-borne flavivirus (strain E5) and a 3' deletion mutant constructed from it exhibit decreased neuroinvasiveness in immunodeficient mice

1 reference

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Construction of infectious cDNA clones for dengue 2 virus: strain 16681 and its attenuated vaccine derivative, strain PDK-53.

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Testing of a dengue 2 live-attenuated vaccine (strain 16681 PDK 53) in ten American volunteers

1 reference

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29 September 2017

Processing of the dengue virus type 2 proteins prM and C-prM.

1 reference

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29 September 2017

Dengue virus-specific memory T cell responses in human volunteers receiving a live attenuated dengue virus type 2 candidate vaccine

1 reference

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29 September 2017

Growth-restricted dengue virus mutants containing deletions in the 5' noncoding region of the RNA genome

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Infection, dissemination, transmission, and biological attributes of dengue-2 PDK53 candidate vaccine virus after oral infection in Aedes aegypti

1 reference

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Passage of yellow fever virus: its effect on infection and transmission rates in Aedes aegypti.

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29 September 2017

Identifiers

10.1128/JVI.79.12.7300-7310.2005

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