(Q27472938)

English

Paired charge-to-alanine mutagenesis of dengue virus type 4 NS5 generates mutants with temperature-sensitive, host range, and mouse attenuation phenotypes

scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Paired charge-to-alanine mutagenesis of dengue virus type 4 NS5 generates mutants with temperature-sensitive, host range, and mouse attenuation phenotypes (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

1 reference

dengue virus protein NS5

1 reference

based on heuristic

inferred from abstract

Stephen S Whitehead

5

object named as

Stephen S Whitehead

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Kathryn A. Hanley

1

object named as

Kathryn A Hanley

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Joseph E Blaney

3

object named as

Joseph E Blaney

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Brian R. Murphy

4

object named as

Brian R Murphy

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

author name string

Jay J Lee

2

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 January 2002

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Journal of Virology

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

76

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

525-531

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Chemical mutagenesis of dengue virus type 4 yields mutant viruses which are temperature sensitive in vero cells or human liver cells and attenuated in mice

1 reference

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21 March 2017

Genetic analysis of the yellow fever virus NS1 protein: identification of a temperature-sensitive mutation which blocks RNA accumulation

1 reference

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21 March 2017

Dengue type 4 virus mutants containing deletions in the 3' noncoding region of the RNA genome: analysis of growth restriction in cell culture and altered viremia pattern and immunogenicity in rhesus monkeys

1 reference

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21 March 2017

Dengue viremia titer, antibody response pattern, and virus serotype correlate with disease severity

1 reference

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21 March 2017

Rapid and efficient site-specific mutagenesis without phenotypic selection

1 reference

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21 March 2017

Recombinant dengue type 1 virus NS5 protein expressed in Escherichia coli exhibits RNA-dependent RNA polymerase activity

1 reference

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21 March 2017

Association between NS3 and NS5 Proteins of Dengue Virus Type 2 in the Putative RNA Replicase Is Linked to Differential Phosphorylation of NS5

1 reference

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Growth of human hepatoma cells lines with differentiated functions in chemically defined medium

1 reference

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The phylogeny of RNA-dependent RNA polymerases of positive-strand RNA viruses

1 reference

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A live attenuated recombinant dengue-4 virus vaccine candidate with restricted capacity for dissemination in mosquitoes and lack of transmission from vaccinees to mosquitoes.

1 reference

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29 September 2017

Attenuation and immunogenicity in humans of a live dengue virus type-4 vaccine candidate with a 30 nucleotide deletion in its 3'-untranslated region.

1 reference

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1 reference

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29 September 2017

A small region of the dengue virus-encoded RNA-dependent RNA polymerase, NS5, confers interaction with both the nuclear transport receptor importin-beta and the viral helicase, NS3.

1 reference

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29 September 2017

Live attenuated tetravalent dengue vaccine

1 reference

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Prospective study of the duration and magnitude of viraemia in children hospitalised during the 1996-1997 dengue-2 outbreak in French Polynesia

1 reference

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29 September 2017

The 37-amino-acid interdomain of dengue virus NS5 protein contains a functional NLS and inhibitory CK2 site.

1 reference

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29 September 2017

The global pandemic of dengue/dengue haemorrhagic fever: current status and prospects for the future

1 reference

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29 September 2017

Conversion of dengue virus replicative form RNA (RF) to replicative intermediate (RI) by nonstructural proteins NS-5 and NS-3.

1 reference

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Early clinical and laboratory indicators of acute dengue illness

1 reference

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29 September 2017

Testing of a dengue 2 live-attenuated vaccine (strain 16681 PDK 53) in ten American volunteers

1 reference

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29 September 2017

Synthesis of dengue virus RNA in vitro: initiation and the involvement of proteins NS3 and NS5.

1 reference

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29 September 2017

The effects of site-directed mutagenesis on the dimerization and secretion of the NS1 protein specified by dengue virus

1 reference

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29 September 2017

Computer-assisted identification of a putative methyltransferase domain in NS5 protein of flaviviruses and lambda 2 protein of reovirus

1 reference

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29 September 2017

Clustered charged-to-alanine mutagenesis of poliovirus RNA-dependent RNA polymerase yields multiple temperature-sensitive mutants defective in RNA synthesis

1 reference

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29 September 2017

Glycosylation mutants of dengue virus NS1 protein

1 reference

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29 September 2017

A live attenuated dengue-1 vaccine candidate (45AZ5) passaged in primary dog kidney cell culture is attenuated and immunogenic for humans

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Dengue-2 vaccine: preparation from a small-plaque virus clone

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Selection of attenuated dengue 4 viruses by serial passage in primary kidney cells. V. Human response to immunization with a candidate vaccine prepared in fetal rhesus lung cells

1 reference

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Mutational effects on protein stability

1 reference

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Newly synthesized dengue-2 virus nonstructural protein NS1 is a soluble protein but becomes partially hydrophobic and membrane-associated after dimerization

1 reference

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Infectious RNA transcribed from stably cloned full-length cDNA of dengue type 4 virus

1 reference

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29 September 2017

Liver biochemical tests and dengue fever

1 reference

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29 September 2017

Recombinant dengue virus type 1 NS3 protein exhibits specific viral RNA binding and NTPase activity regulated by the NS5 protein

1 reference

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1 reference

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27 November 2018

An influenza A live attenuated reassortant virus possessing three temperature-sensitive mutations in the PB2 polymerase gene rapidly loses temperature sensitivity following replication in hamsters

1 reference

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27 November 2018

Identifiers

10.1128/JVI.76.2.525-531.2002

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

ResearchGate publication ID

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