(Q27478187)

English

Role of Divalent Metal Cations in ATP Hydrolysis Catalyzed by the Hepatitis C Virus NS3 Helicase: Magnesium Provides a Bridge for ATP to Fuel Unwinding

scientific article (publication date: 26 January 2007)

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scholarly article

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Role of Divalent Metal Cations in ATP Hydrolysis Catalyzed by the Hepatitis C Virus NS3 Helicase: Magnesium Provides a Bridge for ATP to Fuel Unwinding (English)

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Hepatitis C virus

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based on heuristic

inferred from title

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based on heuristic

inferred from title

object named as

David N Frick

1

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author name string

Sukalyani Banik

2

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Ryan S Rypma

3

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language of work or name

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publication date

26 January 2007

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Journal of Molecular Biology

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365

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4

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1017-32

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RNA translocation and unwinding mechanism of HCV NS3 helicase and its coordination by ATP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829317

21 March 2017

Hepatitis C virus subgenomic replicon requires an active NS3 RNA helicase

1 reference

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21 March 2017

High-resolution structure of the E.coli RecQ helicase catalytic core

1 reference

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21 March 2017

Hepatitis C Virus NS3 ATPases/Helicases from Different Genotypes Exhibit Variations in Enzymatic Properties

1 reference

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21 March 2017

Structure-Based Mutational Analysis of the Hepatitis C Virus NS3 Helicase

1 reference

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Crystal structure of T7 gene 4 ring helicase indicates a mechanism for sequential hydrolysis of nucleotides

1 reference

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Molecular views of viral polyprotein processing revealed by the crystal structure of the hepatitis C virus bifunctional protease-helicase

1 reference

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DNA binding mediates conformational changes and metal ion coordination in the active site of PcrA helicase

1 reference

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Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism

1 reference

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Crystal structure of RNA helicase from genotype 1b hepatitis C virus. A feasible mechanism of unwinding duplex RNA

1 reference

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21 March 2017

Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding

1 reference

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21 March 2017

Structure of the hepatitis C virus RNA helicase domain

1 reference

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21 March 2017

The helicase activity associated with hepatitis C virus nonstructural protein 3 (NS3)

1 reference

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21 March 2017

Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related pestivirus and flavivirus enzymes

1 reference

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21 March 2017

Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites

1 reference

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21 March 2017

NS3 is a serine protease required for processing of hepatitis C virus polyprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829317

21 March 2017

Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829317

21 March 2017

Structure of the recA protein–ADP complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829317

21 March 2017

DNA-induced switch from independent to sequential dTTP hydrolysis in the bacteriophage T7 DNA helicase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829317

21 March 2017

Characterization and mutational analysis of the helicase and NTPase activities of hepatitis C virus full-length NS3 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829317

21 March 2017

Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829317

7 April 2017

C-terminal domain of the hepatitis C virus NS3 protein contains an RNA helicase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829317

7 April 2017

Understanding helicases as a means of virus control.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829317

29 September 2017

Structural and biological identification of residues on the surface of NS3 helicase required for optimal replication of the hepatitis C virus

1 reference

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29 September 2017

Viral and cellular RNA helicases as antiviral targets

1 reference

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29 September 2017

Role of a conserved glutamate residue in the Escherichia coli SecA ATPase mechanism

1 reference

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29 September 2017

Multiple full-length NS3 molecules are required for optimal unwinding of oligonucleotide DNA in vitro

1 reference

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29 September 2017

Electrostatic analysis of the hepatitis C virus NS3 helicase reveals both active and allosteric site locations

1 reference

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29 September 2017

The RNA helicase, nucleotide 5'-triphosphatase, and RNA 5'-triphosphatase activities of Dengue virus protein NS3 are Mg2+-dependent and require a functional Walker B motif in the helicase catalytic core.

1 reference

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29 September 2017

Enhanced nucleic acid binding to ATP-bound hepatitis C virus NS3 helicase at low pH activates RNA unwinding

1 reference

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Direct fluorometric measurement of hepatitis C virus helicase activity

1 reference

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The nonstructural protein 3 protease/helicase requires an intact protease domain to unwind duplex RNA efficiently

1 reference

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Helicases as antiviral drug targets

1 reference

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29 September 2017

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1 reference

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1 reference

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1 reference

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29 September 2017

Spectrophotometric assay for enzyme-mediated unwinding of double-stranded DNA.

1 reference

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29 September 2017

A fluorescence-based assay for monitoring helicase activity

1 reference

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29 September 2017

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1 reference

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1 reference

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Periodic cycles of RNA unwinding and pausing by hepatitis C virus NS3 helicase

1 reference

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The functional interaction of the hepatitis C virus helicase molecules is responsible for unwinding processivity

1 reference

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1 reference

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27 November 2018

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1 reference

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27 November 2018

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1 reference

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27 November 2018

Modulation of the hepatitis C virus RNA-dependent RNA polymerase activity by the non-structural (NS) 3 helicase and the NS4B membrane protein.

1 reference

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27 November 2018

Strand-separating activity of hepatitis C virus helicase in the absence of ATP.

1 reference

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27 November 2018

Inhibition of the hepatitis C virus helicase-associated ATPase activity by the combination of ADP, NaF, MgCl2, and poly(rU). Two ADP binding sites on the enzyme-nucleic acid complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829317

27 November 2018

DNA helicase activity of the hepatitis C virus nonstructural protein 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829317

27 November 2018

Simultaneous Determination of Intracellular Magnesium and pH from the Three 31P NMR Chemical Shifts of ATP

1 reference

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27 November 2018

Single-turnover kinetics of helicase-catalyzed DNA unwinding monitored continuously by fluorescence energy transfer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829317

27 November 2018

Bacteriophage T7 DNA helicase binds dTTP, forms hexamers, and binds DNA in the absence of Mg2+. The presence of dTTP is sufficient for hexamer formation and DNA binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/17084859

12 December 2020

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10.1016/J.JMB.2006.10.023

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Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017

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