(Q27547337)

3'-5'-exoribonuclease activity

4 references

27 March 2018

The exosome subunit Rrp44 plays a direct role in RNA substrate recognition

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08162&geneProductId=UniProtKB:Q08162

27 March 2018

A single subunit, Dis3, is essentially responsible for yeast exosome core activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08162&geneProductId=UniProtKB:Q08162

27 March 2018

The exosome subunit Rrp44 plays a direct role in RNA substrate recognition

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08162&geneProductId=UniProtKB:Q08162

27 March 2018

A single subunit, Dis3, is essentially responsible for yeast exosome core activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08162&geneProductId=UniProtKB:Q08162

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08162&geneProductId=UniProtKB:Q08162

endonuclease activity

1 reference

27 March 2018

endoribonuclease activity

5 references

9 May 2019

The N-terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

Endonucleolytic RNA cleavage by a eukaryotic exosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

The N-terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

Endonucleolytic RNA cleavage by a eukaryotic exosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

7 references

9 May 2019

Subunit architecture of multimeric complexes isolated directly from cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

High-quality binary protein interaction map of the yeast interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

A single subunit, Dis3, is essentially responsible for yeast exosome core activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

Rrp47p is an exosome-associated protein required for the 3' processing of stable RNAs.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

Proteome survey reveals modularity of the yeast cell machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

The yeast exosome functions as a macromolecular cage to channel RNA substrates for degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

Architecture of the yeast Rrp44 exosome complex suggests routes of RNA recruitment for 3' end processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

3'-5'-exoribonuclease activity

IPI

5 references

9 May 2019

A single subunit, Dis3, is essentially responsible for yeast exosome core activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

The exosome subunit Rrp44 plays a direct role in RNA substrate recognition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

A single subunit, Dis3, is essentially responsible for yeast exosome core activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

The exosome subunit Rrp44 plays a direct role in RNA substrate recognition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

IBA

ribonuclease activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08162&geneProductId=UniProtKB:Q08162

cell component

exosome (RNase complex)

1 reference

27 March 2018

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08162&geneProductId=UniProtKB:Q08162

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08162&geneProductId=UniProtKB:Q08162

nuclear exosome (RNase complex)

3 references

9 May 2019

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

Comparative multiplexed mass spectrometric analyses of endogenously expressed yeast nuclear and cytoplasmic exosomes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

cytoplasmic exosome (RNase complex)

IBA

3 references

9 May 2019

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

Comparative multiplexed mass spectrometric analyses of endogenously expressed yeast nuclear and cytoplasmic exosomes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

Human dis3p, which binds to either GTP- or GDP-Ran, complements Saccharomyces cerevisiae dis3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

The proteome of Saccharomyces cerevisiae mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay

HDA

biological process

1 reference

9 May 2019

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

nuclear-transcribed mRNA catabolic process, non-stop decay

IC

1 reference

9 May 2019

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

polyadenylation-dependent snoRNA 3'-end processing

IC

1 reference

9 May 2019

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

nuclear polyadenylation-dependent tRNA catabolic process

IC

5 references

9 May 2019

The exosome subunit Rrp44 plays a direct role in RNA substrate recognition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

Nuclear surveillance and degradation of hypomodified initiator tRNAMet in S. cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

A new yeast poly(A) polymerase complex involved in RNA quality control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

RNA degradation by the exosome is promoted by a nuclear polyadenylation complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

9 May 2019

The exosome subunit Rrp44 plays a direct role in RNA substrate recognition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

A convergence of rRNA and mRNA quality control pathways revealed by mechanistic analysis of nonfunctional rRNA decay

IDA

nonfunctional rRNA decay

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

nuclear mRNA surveillance

1 reference

9 May 2019

Identification of a regulated pathway for nuclear pre-mRNA turnover.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

Functions of the exosome in rRNA, snoRNA and snRNA synthesis

rRNA catabolic process

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08162&geneProductId=UniProtKB:Q08162

nuclear polyadenylation-dependent mRNA catabolic process

1 reference

9 May 2019

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

Biogenesis of the signal recognition particle (SRP) involves import of SRP proteins into the nucleolus, assembly with the SRP-RNA, and Xpo1p-mediated export.

ncRNA 3'-end processing

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

nuclear polyadenylation-dependent CUT catabolic process

1 reference

9 May 2019

Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

poly(A)+ mRNA export from nucleus

1 reference

9 May 2019

Altered RNA processing and export lead to retention of mRNAs near transcription sites and nuclear pore complexes or within the nucleolus.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

RNA phosphodiester bond hydrolysis, endonucleolytic

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08162

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

RNA catabolic process

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08162&geneProductId=UniProtKB:Q08162