(Q27547670)

http://www.ebi.ac.uk/interpro/protein/P38859

P-loop containing nucleoside triphosphate hydrolase

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P38859

DNA replication factor Dna2, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

single-stranded DNA endodeoxyribonuclease activity

A yeast gene required for DNA replication encodes a protein with homology to DNA helicases

IDA

DNA helicase activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

iron-sulfur cluster binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

4 references

9 May 2019

MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

9 May 2019

Proteome survey reveals modularity of the yeast cell machinery

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

9 May 2019

Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

9 May 2019

A yeast replicative helicase, Dna2 helicase, interacts with yeast FEN-1 nuclease in carrying out its essential function

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

5'-3' DNA helicase activity

IPI

1 reference

9 May 2019

Dna2 exhibits a unique strand end-dependent helicase function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

5'-flap endonuclease activity

IDA

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

9 May 2019

Dna2p helicase/nuclease is a tracking protein, like FEN1, for flap cleavage during Okazaki fragment maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

3 references

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38859&geneProductId=UniProtKB:P38859

27 February 2018

Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38859&geneProductId=UniProtKB:P38859

27 February 2018

Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38859&geneProductId=UniProtKB:P38859

1 reference

27 February 2018

Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38859&geneProductId=UniProtKB:P38859

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

site of double-strand break

TAS

1 reference

9 May 2019

Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

4 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38859&geneProductId=UniProtKB:P38859

10 September 2018

Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38859&geneProductId=UniProtKB:P38859

10 September 2018

Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38859&geneProductId=UniProtKB:P38859

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38859&geneProductId=UniProtKB:P38859

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

9 May 2019

Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

9 May 2019

Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

9 May 2019

Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

lagging strand elongation

HDA

biological process

2 references

9 May 2019

Dna2 mutants reveal interactions with Dna polymerase alpha and Ctf4, a Pol alpha accessory factor, and show that full Dna2 helicase activity is not essential for growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

9 May 2019

Accumulation of single-stranded DNA and destabilization of telomeric repeats in yeast mutant strains carrying a deletion of RAD27.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

meiotic DNA double-strand break processing

IMP

1 reference

9 May 2019

Processing of meiotic DNA double strand breaks requires cyclin-dependent kinase and multiple nucleases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

DNA-dependent DNA replication

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

1 reference

9 May 2019

Dynamic localization of an Okazaki fragment processing protein suggests a novel role in telomere replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

DNA double-strand break processing

IMP

3 references

9 May 2019

Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

9 May 2019

Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

9 May 2019

Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

nucleic acid phosphodiester bond hydrolysis

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

DNA replication, Okazaki fragment processing

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

replication fork reversal

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38859

DNA replication factor Dna2, N-terminal

IBA

has part(s)

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P38859

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference