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Leo1p YOR123C
fungal protein found in Saccharomyces cerevisiae S288c
YOR123C
Leo1p
LEO1
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P38439
subclass of
protein
1 reference
stated in
NCBI Gene
retrieved
10 December 2016
Entrez Gene ID
854290
part of
Leo1-like protein
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P38439
found in taxon
Saccharomyces cerevisiae S288c
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P38439
encoded by
LEO1
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P38439
molecular function
RNA polymerase II C-terminal domain phosphoserine binding
determination method
IDA
1 reference
retrieved
27 March 2018
stated in
Pol II CTD kinases Bur1 and Kin28 promote Spt5 CTR-independent recruitment of Paf1 complex
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P38439&geneProductId=UniProtKB:P38439
determination method
IDA
RNA binding
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Leo1 subunit of the yeast paf1 complex binds RNA and contributes to complex recruitment
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IDA
protein binding
determination method
IPI
5 references
retrieved
9 May 2019
stated in
High-quality binary protein interaction map of the yeast interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IPI
retrieved
9 May 2019
stated in
Mpk1 MAPK association with the Paf1 complex blocks Sen1-mediated premature transcription termination.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IPI
retrieved
9 May 2019
stated in
RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IPI
retrieved
9 May 2019
stated in
The Paf1 complex physically and functionally associates with transcription elongation factors in vivo
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IPI
retrieved
9 May 2019
stated in
Proteome survey reveals modularity of the yeast cell machinery
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IPI
transcription coregulator activity
determination method
IPI
1 reference
retrieved
9 May 2019
stated in
The Paf1 complex physically and functionally associates with transcription elongation factors in vivo
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IPI
RNA polymerase II C-terminal domain phosphoserine binding
determination method
IBA
IDA
2 references
retrieved
9 May 2019
stated in
Pol II CTD kinases Bur1 and Kin28 promote Spt5 CTR-independent recruitment of Paf1 complex
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IBA
cell component
Cdc73/Paf1 complex
determination method
IEA
IPI
3 references
retrieved
9 May 2019
stated in
The Paf1 complex physically and functionally associates with transcription elongation factors in vivo
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IPI
retrieved
9 May 2019
stated in
Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IPI
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IEA
nucleoplasm
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P38439
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IEA
nucleus
determination method
IDA
IEA
2 references
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P38439
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P38439&geneProductId=UniProtKB:P38439
determination method
IEA
retrieved
27 March 2018
stated in
Separation of the Saccharomyces cerevisiae Paf1 complex from RNA polymerase II results in changes in its subnuclear localization
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P38439&geneProductId=UniProtKB:P38439
determination method
IDA
nucleus
determination method
IBA
IDA
IEA
3 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P38439
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IEA
retrieved
9 May 2019
stated in
Separation of the Saccharomyces cerevisiae Paf1 complex from RNA polymerase II results in changes in its subnuclear localization
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IBA
biological process
DNA-templated transcription, termination
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Effects of the Paf1 complex and histone modifications on snoRNA 3'-end formation reveal broad and locus-specific regulation
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IMP
histone modification
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IEA
regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P38439
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P38439&geneProductId=UniProtKB:P38439
determination method
IEA
transcription elongation from RNA polymerase II promoter
determination method
IEA
IGI
2 references
retrieved
9 May 2019
stated in
The Paf1 complex physically and functionally associates with transcription elongation factors in vivo
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IGI
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IEA
regulation of transcription-coupled nucleotide-excision repair
determination method
IGI
1 reference
retrieved
9 May 2019
stated in
Diverse roles of RNA polymerase II-associated factor 1 complex in different subpathways of nucleotide excision repair
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IGI
positive regulation of transcription elongation from RNA polymerase I promoter
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
The RNA polymerase-associated factor 1 complex (Paf1C) directly increases the elongation rate of RNA polymerase I and is required for efficient regulation of rRNA synthesis.
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IDA
histone H3-K4 trimethylation
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Leo1 subunit of the yeast paf1 complex binds RNA and contributes to complex recruitment
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IMP
positive regulation of transcription elongation from RNA polymerase II promoter
determination method
IMP
1 reference
retrieved
27 March 2018
stated in
Molecular evidence indicating that the yeast PAF complex is required for transcription elongation
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P38439&geneProductId=UniProtKB:P38439
determination method
IMP
transcription, DNA-templated
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P38439
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P38439&geneProductId=UniProtKB:P38439
determination method
IEA
chromatin organization
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Leo1 subunit of the yeast paf1 complex binds RNA and contributes to complex recruitment
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IMP
regulation of histone H2B conserved C-terminal lysine ubiquitination
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Direct Bre1-Paf1 complex interactions and RING finger-independent Bre1-Rad6 interactions mediate histone H2B ubiquitylation in yeast
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IDA
positive regulation of transcription elongation from RNA polymerase II promoter
determination method
IBA
IMP
2 references
retrieved
9 May 2019
stated in
Molecular evidence indicating that the yeast PAF complex is required for transcription elongation
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IMP
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38439
determination method
IBA
Identifiers
RefSeq protein ID
NP_014766
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
854290
UniProt protein ID
P38439
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P38439
Ensembl protein ID
YOR123C
1 reference
stated in
ensembl Release 106
Ensembl protein ID
YOR123C
Saccharomyces Genome Database ID
S000005649
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
854290
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