(Q27549478)

English

Tof1p YNL273W

fungal protein found in Saccharomyces cerevisiae S288c

Tof1p
YNL273W
TOF1

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

10 December 2016

Timeless protein family

1 reference

based on heuristic

inferred from protein domain or family

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

protein binding

determination method

7 references

9 May 2019

High-quality binary protein interaction map of the yeast interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

9 May 2019

Identification of protein complexes required for efficient sister chromatid cohesion

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

9 May 2019

Mrc1 phosphorylation in response to DNA replication stress is required for Mec1 accumulation at the stalled fork

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

9 May 2019

Defining the budding yeast chromatin-associated interactome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

9 May 2019

Uncoupling of unwinding from DNA synthesis implies regulation of MCM helicase by Tof1/Mrc1/Csm3 checkpoint complex.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

9 May 2019

Proteome survey reveals modularity of the yeast cell machinery

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

9 May 2019

S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

molecular function

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

replication fork protection complex

determination method

1 reference

5 June 2018

GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53840&geneProductId=UniProtKB:P53840

determination method

nuclear replication fork

determination method

1 reference

9 May 2019

Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

determination method

1 reference

9 May 2019

The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

nuclear chromosome

determination method

1 reference

14 February 2019

S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

determination method

3 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

9 May 2019

The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

biological process

negative regulation of DNA replication

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

DNA replication

determination method

1 reference

9 May 2019

Mrc1 and Tof1 promote replication fork progression and recovery independently of Rad53.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

determination method

3 references

5 June 2018

Genetic analysis of Saccharomyces cerevisiae H2A serine 129 mutant suggests a functional relationship between H2A and the sister-chromatid cohesion partners Csm3-Tof1 for the repair of topoisomerase I-induced DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53840&geneProductId=UniProtKB:P53840

determination method

5 June 2018

Genetic analysis of Saccharomyces cerevisiae H2A serine 129 mutant suggests a functional relationship between H2A and the sister-chromatid cohesion partners Csm3-Tof1 for the repair of topoisomerase I-induced DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53840&geneProductId=UniProtKB:P53840

determination method

5 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53840&geneProductId=UniProtKB:P53840

determination method

replication fork arrest

determination method

3 references

5 June 2018

The Tof1p-Csm3p protein complex counteracts the Rrm3p helicase to control replication termination of Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53840&geneProductId=UniProtKB:P53840

determination method

5 June 2018

Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53840&geneProductId=UniProtKB:P53840

determination method

5 June 2018

Mrc1 and Tof1 regulate DNA replication forks in different ways during normal S phase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53840&geneProductId=UniProtKB:P53840

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

maintenance of DNA repeat elements

determination method

1 reference

9 May 2019

Mrc1, Tof1 and Csm3 inhibit CAG.CTG repeat instability by at least two mechanisms.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

mitotic sister chromatid cohesion

determination method

4 references

9 May 2019

Genetic dissection of parallel sister-chromatid cohesion pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

9 May 2019

Identification of protein complexes required for efficient sister chromatid cohesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

9 May 2019

Genetic dissection of parallel sister-chromatid cohesion pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

9 May 2019

Identification of protein complexes required for efficient sister chromatid cohesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

cellular response to DNA damage stimulus

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

DNA replication checkpoint signaling

determination method

3 references

14 February 2019

S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

14 February 2019

S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

determination method

4 references

9 May 2019

Genetic analysis of Saccharomyces cerevisiae H2A serine 129 mutant suggests a functional relationship between H2A and the sister-chromatid cohesion partners Csm3-Tof1 for the repair of topoisomerase I-induced DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

9 May 2019

Genetic analysis of Saccharomyces cerevisiae H2A serine 129 mutant suggests a functional relationship between H2A and the sister-chromatid cohesion partners Csm3-Tof1 for the repair of topoisomerase I-induced DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

replication fork arrest

determination method

4 references

9 May 2019

Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

9 May 2019

Mrc1 and Tof1 regulate DNA replication forks in different ways during normal S phase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

9 May 2019

The Tof1p-Csm3p protein complex counteracts the Rrm3p helicase to control replication termination of Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

replication fork protection

determination method

3 references

9 May 2019

Replication stalling at unstable inverted repeats: interplay between DNA hairpins and fork stabilizing proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

9 May 2019

The Tof1p-Csm3p protein complex counteracts the Rrm3p helicase to control replication termination of Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53840

determination method

Timeless protein

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P53840

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Saccharomyces Genome Database ID

1 reference

20 March 2022

Sitelinks

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