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DEAH-box ATP-dependent RNA helicase PRP43 YGL120C
fungal protein found in Saccharomyces cerevisiae S288c
PRP43
YGL120C
DEAH-box ATP-dependent RNA helicase PRP43
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P53131
subclass of
protein
1 reference
stated in
NCBI Gene
retrieved
10 December 2016
Entrez Gene ID
852757
part of
P-loop containing nucleoside triphosphate hydrolase
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P53131
Helicase superfamily 1/2, ATP-binding domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Helicase, C-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
DEAD/DEAH box helicase
1 reference
based on heuristic
inferred from protein domain or family
Domain of unknown function DUF1605, protein family
1 reference
based on heuristic
inferred from protein domain or family
DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Saccharomyces cerevisiae S288c
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P53131
encoded by
PRP43
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P53131
molecular function
ATP binding
determination method
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P53131
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IEA
helicase activity
determination method
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P53131
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IEA
hydrolase activity
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P53131
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IEA
nucleotide binding
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P53131
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IEA
nucleic acid binding
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IEA
protein binding
determination method
IPI
8 references
retrieved
9 May 2019
stated in
The splicing ATPase prp43p is a component of multiple preribosomal particles
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IPI
retrieved
9 May 2019
stated in
The ATPase and helicase activities of Prp43p are stimulated by the G-patch protein Pfa1p during yeast ribosome biogenesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IPI
retrieved
9 May 2019
stated in
Prp43p contains a processive helicase structural architecture with a specific regulatory domain
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IPI
retrieved
9 May 2019
stated in
The SSU processome interactome in Saccharomyces cerevisiae reveals novel protein subcomplexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IPI
retrieved
9 May 2019
stated in
A protein interaction map of the LSU processome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IPI
retrieved
9 May 2019
stated in
Proteome survey reveals modularity of the yeast cell machinery
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IPI
retrieved
9 May 2019
stated in
Spliceosome disassembly catalyzed by Prp43 and its associated components Ntr1 and Ntr2.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IPI
retrieved
9 May 2019
stated in
Assigning function to yeast proteins by integration of technologies.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IPI
RNA binding
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IBA
3'-5' RNA helicase activity
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IBA
mRNA binding
determination method
HDA
1 reference
retrieved
9 May 2019
stated in
Global analysis of yeast mRNPs
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
HDA
cell component
post-mRNA release spliceosomal complex
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Prp43 is an essential RNA-dependent ATPase required for release of lariat-intron from the spliceosome
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IMP
nucleus
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P53131
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IEA
mitochondrion
determination method
HDA
2 references
retrieved
9 May 2019
stated in
Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
HDA
retrieved
9 May 2019
stated in
The proteome of Saccharomyces cerevisiae mitochondria
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
HDA
90S preribosome
determination method
HDA
1 reference
retrieved
9 May 2019
stated in
90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
HDA
biological process
mRNA processing
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P53131
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IEA
spliceosomal complex disassembly
determination method
IDA
IGI
2 references
retrieved
9 May 2019
stated in
Ntr1 activates the Prp43 helicase to trigger release of lariat-intron from the spliceosome
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IGI
retrieved
9 May 2019
stated in
Spliceosome disassembly catalyzed by Prp43 and its associated components Ntr1 and Ntr2.
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IDA
RNA splicing
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P53131
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IEA
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
The splicing factor Prp43p, a DEAH box ATPase, functions in ribosome biogenesis
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IMP
maturation of SSU-rRNA
determination method
IGI
1 reference
retrieved
9 May 2019
stated in
RNA helicase Prp43 and its co-factor Pfa1 promote 20 to 18 S rRNA processing catalyzed by the endonuclease Nob1.
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IGI
maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
The splicing factor Prp43p, a DEAH box ATPase, functions in ribosome biogenesis
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IMP
ribosomal large subunit biogenesis
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
The splicing factor Prp43p, a DEAH box ATPase, functions in ribosome biogenesis
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IMP
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
The splicing factor Prp43p, a DEAH box ATPase, functions in ribosome biogenesis
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IMP
rRNA processing
determination method
IMP
2 references
retrieved
9 May 2019
stated in
The splicing ATPase prp43p is a component of multiple preribosomal particles
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IMP
retrieved
9 May 2019
stated in
Prp43p is a DEAH-box spliceosome disassembly factor essential for ribosome biogenesis
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53131
determination method
IMP
has part(s)
Domain of unknown function DUF1605
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P53131
Helicase-associated domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P53131
DEAD/DEAH box helicase domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P53131
DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P53131
Helicase superfamily 1/2, ATP-binding domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P53131
Helicase, C-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P53131
Identifiers
RefSeq protein ID
NP_011395
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
852757
UniProt protein ID
P53131
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P53131
Ensembl protein ID
YGL120C
1 reference
stated in
ensembl Release 106
Ensembl protein ID
YGL120C
Saccharomyces Genome Database ID
S000003088
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
852757
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