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(Q27551249)
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English
Srb5p YGR104C
fungal protein found in Saccharomyces cerevisiae S288c
Srb5p
YGR104C
SRB5
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P32585
subclass of
protein
1 reference
stated in
NCBI Gene
retrieved
10 December 2016
Entrez Gene ID
852996
part of
Mediator complex, subunit Med18
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P32585
found in taxon
Saccharomyces cerevisiae S288c
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P32585
encoded by
SRB5
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P32585
molecular function
transcription coregulator activity
determination method
IBA
IEA
4 references
retrieved
27 February 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P32585&geneProductId=UniProtKB:P32585
determination method
IEA
retrieved
27 February 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P32585&geneProductId=UniProtKB:P32585
determination method
IBA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585
determination method
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585
determination method
IBA
RNA polymerase II core promoter sequence-specific DNA binding
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Mediator recruitment to heat shock genes requires dual Hsf1 activation domains and mediator tail subunits Med15 and Med16
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585
determination method
IDA
protein binding
determination method
IPI
6 references
retrieved
9 May 2019
stated in
The Soh1/MED31 protein is an ancient component of Schizosaccharomyces pombe and Saccharomyces cerevisiae Mediator
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585
determination method
IPI
retrieved
9 May 2019
stated in
Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585
determination method
IPI
retrieved
9 May 2019
stated in
Proteome survey reveals modularity of the yeast cell machinery
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585
determination method
IPI
retrieved
9 May 2019
stated in
A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585
determination method
IPI
retrieved
9 May 2019
stated in
Identification, structure, and functional requirement of the Mediator submodule Med7N/31
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585
determination method
IPI
retrieved
9 May 2019
stated in
A high resolution protein interaction map of the yeast Mediator complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585
determination method
IPI
transcription coregulator activity
determination method
IEA
1 reference
retrieved
10 September 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P32585&geneProductId=UniProtKB:P32585
determination method
IEA
cell component
mediator complex
determination method
IBA
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585
determination method
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585
determination method
IBA
core mediator complex
determination method
IDA
1 reference
retrieved
21 June 2018
stated in
Activator-specific requirement of yeast mediator proteins for RNA polymerase II transcriptional activation
GOA
curator
SGD
Saccharomyces Genome Database ID
S000003336
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P32585&geneProductId=UniProtKB:P32585
determination method
IDA
nucleus
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P32585
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585
determination method
IEA
core mediator complex
determination method
IBA
IDA
2 references
retrieved
9 May 2019
stated in
Activator-specific requirement of yeast mediator proteins for RNA polymerase II transcriptional activation
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585
determination method
IBA
biological process
regulation of transcription by RNA polymerase II
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585
determination method
IEA
transcription open complex formation at RNA polymerase II promoter
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Activation of a poised RNAPII-dependent promoter requires both SAGA and mediator
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585
determination method
IMP
RNA polymerase II preinitiation complex assembly
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast.
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585
determination method
IDA
transcription, DNA-templated
determination method
IEA
1 reference
retrieved
21 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P32585
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P32585&geneProductId=UniProtKB:P32585
determination method
IEA
termination of RNA polymerase II transcription
determination method
IMP
1 reference
retrieved
21 June 2018
stated in
Srb5/Med18-mediated termination of transcription is dependent on gene looping
GOA
curator
SGD
Saccharomyces Genome Database ID
S000003336
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P32585&geneProductId=UniProtKB:P32585
determination method
IMP
positive regulation of transcription by RNA polymerase II
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II.
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585
determination method
IDA
regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
21 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P32585
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P32585&geneProductId=UniProtKB:P32585
determination method
IEA
termination of RNA polymerase II transcription
determination method
IBA
IMP
2 references
retrieved
9 May 2019
stated in
Srb5/Med18-mediated termination of transcription is dependent on gene looping
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585
determination method
IMP
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32585
determination method
IBA
Identifiers
RefSeq protein ID
NP_011618
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
852996
UniProt protein ID
P32585
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P32585
Ensembl protein ID
YGR104C
1 reference
stated in
ensembl Release 106
Ensembl protein ID
YGR104C
Saccharomyces Genome Database ID
S000003336
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
852996
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