(Q27938886)

1 December 2016

title

Mediator recruitment to heat shock genes requires dual Hsf1 activation domains and mediator tail subunits Med15 and Med16 (English)

1 reference

Stress-responsive transcription factor HSF1 YGL073W

1 December 2016

0 references

1 reference

Srb5p YGR104C

1 reference

Med4p YOR174W

1 reference

Sin4p YNL236W

1 reference

Gal11p YOL051W

1 reference

Pgd1p YGL025C

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Cyclin-dependent protein serine/threonine kinase regulator SSN8 YNL025C

1 reference

Srb4p YER022W

1 reference

Journal of Biological Chemistry

author name string

Sunyoung Kim

series ordinal

1

0 references

David S Gross

series ordinal

2

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language of work or name

English

0 references

publication date

26 April 2013

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published in

1 reference

describes a project that uses

1 December 2016

volume

288

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issue

17

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page(s)

12197-213

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ImageQuant

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3636903/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Mediator head subcomplex Med11/22 contains a common helix bundle building block with a specific function in transcription initiation complex stabilization

20 March 2017

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Direct interaction of RNA polymerase II and mediator required for transcription in vivo.

20 March 2017

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Differential roles of transcriptional mediator subunits in regulation of multidrug resistance gene expression in Saccharomyces cerevisiae.

20 March 2017

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Mechanism of Mediator recruitment by tandem Gcn4 activation domains and three Gal11 activator-binding domains

20 March 2017

1 reference

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Mediator head module structure and functional interactions

20 March 2017

1 reference

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Activator Gcn4 employs multiple segments of Med15/Gal11, including the KIX domain, to recruit mediator to target genes in vivo

20 March 2017

1 reference

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Mediator structural conservation and implications for the regulation mechanism

20 March 2017

1 reference

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Mediator-dependent recruitment of TFIIH modules in preinitiation complex

20 March 2017

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Different requirements of the SWI/SNF complex for robust nucleosome displacement at promoters of heat shock factor and Msn2- and Msn4-regulated heat shock genes

20 March 2017

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20 March 2017

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A functional module of yeast mediator that governs the dynamic range of heat-shock gene expression

20 March 2017

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Mediator expression profiling epistasis reveals a signal transduction pathway with antagonistic submodules and highly specific downstream targets

20 March 2017

1 reference

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Simultaneous recruitment of coactivators by Gcn4p stimulates multiple steps of transcription in vivo

20 March 2017

1 reference

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The Saccharomyces cerevisiae Srb8-Srb11 complex functions with the SAGA complex during Gal4-activated transcription

20 March 2017

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A triad of subunits from the Gal11/tail domain of Srb mediator is an in vivo target of transcriptional activator Gcn4p

20 March 2017

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Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation

20 March 2017

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The Swi5 activator recruits the Mediator complex to the HO promoter without RNA polymerase II.

20 March 2017

1 reference

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Negative regulation of Gcn4 and Msn2 transcription factors by Srb10 cyclin-dependent kinase

20 March 2017

1 reference

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Srb7p is a physical and physiological target of Tup1p

20 March 2017

1 reference

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Genomic expression programs in the response of yeast cells to environmental changes

20 March 2017

1 reference

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Srb7p is essential for the activation of a subset of genes

20 March 2017

1 reference

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Mediator of Transcriptional Regulation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

The Skn7 response regulator of Saccharomyces cerevisiae interacts with Hsf1 in vivo and is required for the induction of heat shock genes by oxidative stress

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Nuclear proteins Nut1p and Nut2p cooperate to negatively regulate a Swi4p-dependent lacZ reporter gene in Saccharomyces cerevisiae

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Requirement for Hsp90 and a CyP-40-type cyclophilin in negative regulation of the heat shock response

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Crystal structure of the DNA binding domain of the heat shock transcription factor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Dissecting the regulatory circuitry of a eukaryotic genome

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Independent recruitment in vivo by Gal4 of two complexes required for transcription

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Mediator subunit Gal11p/MED15 is required for fatty acid-dependent gene activation by yeast transcription factor Oaf1p

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

CDK8 is a stimulus-specific positive coregulator of p53 target genes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Different upstream transcriptional activators have distinct coactivator requirements

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Mechanisms of Mediator complex action in transcriptional activation.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Role of Mediator in regulating Pol II elongation and nucleosome displacement in Saccharomyces cerevisiae

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Sumoylation of transcription factor Gcn4 facilitates its Srb10-mediated clearance from promoters in yeast

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Facilitated assembly of the preinitiation complex by separated tail and head/middle modules of the mediator

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Distinct role of Mediator tail module in regulation of SAGA-dependent, TATA-containing genes in yeast

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Histone modifications influence mediator interactions with chromatin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

SAGA and Rpd3 chromatin modification complexes dynamically regulate heat shock gene structure and expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Genome-wide analysis reveals new roles for the activation domains of the Saccharomyces cerevisiae heat shock transcription factor (Hsf1) during the transient heat shock response

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Genome-wide location of the coactivator mediator: Binding without activation and transient Cdk8 interaction on DNA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Independent recruitment of mediator and SAGA by the activator Met4

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

The structural and functional role of Med5 in the yeast Mediator tail module

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Targets of the Gal4 transcription activator in functional transcription complexes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Domain-wide displacement of histones by activated heat shock factor occurs independently of Swi/Snf and is not correlated with RNA polymerase II density

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Function of a eukaryotic transcription activator during the transcription cycle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Genome-wide analysis of the biology of stress responses through heat shock transcription factor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Association of the Mediator complex with enhancers of active genes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Structural organization of yeast and mammalian mediator complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

An activator binding module of yeast RNA polymerase II holoenzyme

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Cooperative binding of heat shock factor to the yeast HSP82 promoter in vivo and in vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Cloning-free PCR-based allele replacement methods

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Heat shock factor gains access to the yeast HSC82 promoter independently of other sequence-specific factors and antagonizes nucleosomal repression of basal and induced transcription

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Conditional silencing: the HMRE mating-type silencer exerts a rapidly reversible position effect on the yeast HSP82 heat shock gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Mediator phosphorylation prevents stress response transcription during non-stress conditions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Sequential recruitment of SAGA and TFIID in a genomic response to DNA damage in Saccharomyces cerevisiae

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Mediator, not holoenzyme, is directly recruited to the heat shock promoter by HSF upon heat shock

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636903

The Med8 mediator subunit interacts with the Rpb4 subunit of RNA polymerase II and Ace2 transcriptional activator in Schizosaccharomyces pombe.

2 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.449553

A conserved mediator hinge revealed in the structure of the MED7.MED21 (Med7.Srb7) heterodimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.449553

The tumor suppressor p53 associates with gene coding regions and co-traverses with elongating RNA polymerase II in an in vivo model

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.449553

A genome-wide housekeeping role for TFIID and a highly regulated stress-related role for SAGA in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.449553

Regulation of transcriptional activation domain function by ubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.449553

MED23 mutation links intellectual disability to dysregulation of immediate early gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.449553

Cdk1 Triggers Association of RNA Polymerase to Cell Cycle Promoters Only after Recruitment of the Mediator by SBF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.449553

Structure of the yeast RNA polymerase II holoenzyme: Mediator conformation and polymerase interaction

21 January 2018

1 reference

12 December 2020

Silenced chromatin is permissive to activator binding and PIC recruitment

1 reference

12 December 2020

Trimerization of a yeast transcriptional activator via a coiled-coil motif

1 reference

12 December 2020

Yeast heat shock factor contains separable transient and sustained response transcriptional activators

1 reference

12 December 2020

Conserved structures of mediator and RNA polymerase II holoenzyme

1 reference

12 December 2020

Activator-specific recruitment of Mediator in vivo

1 reference

12 December 2020

Med19(Rox3) regulates Intermodule interactions in the Saccharomyces cerevisiae mediator complex.

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M112.449553

0 references

PMC publication ID

3636903

0 references

1 reference