(Q27552983)

Ribonuclease H-like superfamily

1 reference

DNA polymerase epsilon catalytic subunit

1 reference

DNA-directed DNA polymerase, family B, exonuclease domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

DNA polymerase epsilon, catalytic subunit A, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

DNA-directed DNA polymerase, family B, multifunctional domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

iron-sulfur cluster binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

single-stranded DNA binding

1 reference

9 May 2019

Double‐stranded DNA binding properties of Saccharomyces cerevisiae DNA polymerase ɛ and of the Dpb3p‐Dpb4p subassembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

nucleotidyltransferase activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

4 iron, 4 sulfur cluster binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

2 references

DNA-directed DNA polymerase activity

4 references

27 February 2018

DNA polymerase II, the probable homolog of mammalian DNA polymerase epsilon, replicates chromosomal DNA in the yeast Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21951&geneProductId=UniProtKB:P21951

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21951&geneProductId=UniProtKB:P21951

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21951&geneProductId=UniProtKB:P21951

27 February 2018

Structure of Saccharomyces cerevisiae DNA polymerase epsilon by cryo-electron microscopy.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21951&geneProductId=UniProtKB:P21951

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

single-stranded DNA 3'-5' exodeoxyribonuclease activity

1 reference

27 February 2018

Eukaryotic DNA polymerase amino acid sequence required for 3'----5' exonuclease activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21951&geneProductId=UniProtKB:P21951

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

4 references

9 May 2019

Structure of Saccharomyces cerevisiae DNA polymerase epsilon by cryo-electron microscopy.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

9 May 2019

The quaternary structure of DNA polymerase epsilon from Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

9 May 2019

Coordinated control of replication and transcription by a SAPK protects genomic integrity.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

9 May 2019

Proteome survey reveals modularity of the yeast cell machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

DNA-directed DNA polymerase activity

5 references

9 May 2019

DNA polymerase II, the probable homolog of mammalian DNA polymerase epsilon, replicates chromosomal DNA in the yeast Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

9 May 2019

Structure of Saccharomyces cerevisiae DNA polymerase epsilon by cryo-electron microscopy.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

1 reference

9 May 2019

Global analysis of yeast mRNPs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

epsilon DNA polymerase complex

HDA

cell component

3 references

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21951&geneProductId=UniProtKB:P21951

27 February 2018

The quaternary structure of DNA polymerase epsilon from Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21951&geneProductId=UniProtKB:P21951

27 February 2018

Purification and characterization of DNA polymerase II from the yeast Saccharomyces cerevisiae. Identification of the catalytic core and a possible holoenzyme form of the enzyme

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21951&geneProductId=UniProtKB:P21951

epsilon DNA polymerase complex

IDA

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

9 May 2019

The quaternary structure of DNA polymerase epsilon from Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

9 May 2019

Purification and characterization of DNA polymerase II from the yeast Saccharomyces cerevisiae. Identification of the catalytic core and a possible holoenzyme form of the enzyme

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

mitotic sister chromatid cohesion

biological process

1 reference

9 May 2019

Saccharomyces cerevisiae DNA polymerase epsilon and polymerase sigma interact physically and functionally, suggesting a role for polymerase epsilon in sister chromatid cohesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

nucleotide-excision repair, DNA gap filling

1 reference

27 February 2018

Accessibility of DNA polymerases to repair synthesis during nucleotide excision repair in yeast cell-free extracts

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21951&geneProductId=UniProtKB:P21951

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

mitotic DNA replication checkpoint signaling

1 reference

9 May 2019

Role of the putative zinc finger domain of Saccharomyces cerevisiae DNA polymerase epsilon in DNA replication and the S/M checkpoint pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

1 reference

9 May 2019

DNA repair synthesis during base excision repair in vitro is catalyzed by DNA polymerase epsilon and is influenced by DNA polymerases alpha and delta in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

double-strand break repair

1 reference

9 May 2019

Double-strand break repair in yeast requires both leading and lagging strand DNA polymerases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

error-prone translesion synthesis

1 reference

9 May 2019

Translesion synthesis of abasic sites by yeast DNA polymerase epsilon

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

DNA replication proofreading

IDA

1 reference

9 May 2019

Increased mutagenesis and unique mutation signature associated with mitotic gene conversion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

leading strand elongation

1 reference

27 February 2018

Yeast DNA polymerase epsilon participates in leading-strand DNA replication

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21951&geneProductId=UniProtKB:P21951

mitotic intra-S DNA damage checkpoint signaling

4 references

9 May 2019

Mrc1 and DNA polymerase epsilon function together in linking DNA replication and the S phase checkpoint

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

9 May 2019

RAD9 and DNA polymerase epsilon form parallel sensory branches for transducing the DNA damage checkpoint signal in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

9 May 2019

RAD9 and DNA polymerase epsilon form parallel sensory branches for transducing the DNA damage checkpoint signal in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

9 May 2019

Mrc1 and DNA polymerase epsilon function together in linking DNA replication and the S phase checkpoint

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

base-excision repair, gap-filling

IGI

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

nucleic acid phosphodiester bond hydrolysis

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

DNA replication proofreading

3 references

9 May 2019

Mismatch repair-independent increase in spontaneous mutagenesis in yeast lacking non-essential subunits of DNA polymerase ε.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

9 May 2019

Eukaryotic DNA polymerase amino acid sequence required for 3'----5' exonuclease activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21951

DNA polymerase epsilon, catalytic subunit A, C-terminal

has part(s)

1 reference

DNA-directed DNA polymerase, family B, multifunctional domain

1 reference

DNA-directed DNA polymerase, family B, exonuclease domain

1 reference

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference