(Q27620456)

English

The pre-hydrolysis state of p21(ras) in complex with GTP: new insights into the role of water molecules in the GTP hydrolysis reaction of ras-like proteins

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10574788%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

The pre-hydrolysis state of p21(ras) in complex with GTP: new insights into the role of water molecules in the GTP hydrolysis reaction of ras-like proteins (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10574788%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10574788%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

author name string

A J Scheidig

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10574788%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

C Burmester

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10574788%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

publication date

1 November 1999

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10574788%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10574788%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10574788%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

11

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10574788%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1311-1324

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10574788%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

The GTPase superfamily: a conserved switch for diverse cell functions

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

G protein mechanisms: insights from structural analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The interaction of Ras with GTPase-activating proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Probing the role of loop 2 in Ras function with unnatural amino acids

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of glutamine-61 in the hydrolysis of GTP by p21H-ras: an experimental and theoretical study.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

X-ray crystal structures of transforming p21 ras mutants suggest a transition-state stabilization mechanism for GTP hydrolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Solution structure and dynamics of ras p21.GDP determined by heteronuclear three- and four-dimensional NMR spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Regional polysterism in the GTP-bound form of the human c-Ha-Ras protein

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Ligand-induced conformational changes in ras p21: a normal mode and energy minimization analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Substrate-assisted catalysis as a mechanism for GTP hydrolysis of p21ras and other GTP-binding proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Biochemical and crystallographic characterization of a complex of c-Ha-ras p21 and caged GTP with flash photolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystallographic studies on p21(H-ras) using the synchrotron Laue method: improvement of crystal quality and monitoring of the GTPase reaction at different time points

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal structures of the small G protein Rap2A in complex with its substrate GTP, with GDP and with GTPgammaS.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

X-ray crystal structure analysis of the catalytic domain of the oncogene product p21H-ras complexed with caged GTP and mant dGppNHp

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Three-dimensional structures and properties of a transforming and a nontransforming glycine-12 mutant of p21H-ras

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Substrate and Product Structural Requirements for Binding of Nucleotides to H-ras p21: The Mechanism of Discrimination between Guanosine and Adenosine Nucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

ICM?A new method for protein modeling and design: Applications to docking and structure prediction from the distorted native conformation

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal structure of active elongation factor Tu reveals major domain rearrangements

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The crystal structure of elongation factor EF-Tu from Thermus aquaticus in the GTP conformation

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The 2.2 A crystal structure of transducin-alpha complexed with GTP gamma S

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Transient Kinetic Studies on the Interaction of Ras and the Ras-Binding Domain of c-Raf-1 Reveal Rapid Equilibration of the Complex†

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

How does the switch II region of G-domains work?

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Macromolecular Cryocrystallography

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanism of GTP hydrolysis by p21N-ras catalyzed by GAP: studies with a fluorescent GTP analogue

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Hydrolysis of GTP by p21NRAS, the NRAS protooncogene product, is accompanied by a conformational change in the wild-type protein: use of a single fluorescent probe at the catalytic site

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal structures at 2.2 A resolution of the catalytic domains of normal ras protein and an oncogenic mutant complexed with GDP

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanistic analysis of the observed linear free energy relationships in p21ras and related systems.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Ras-catalyzed hydrolysis of GTP: a new perspective from model studies

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Preferential inhibition of the oncogenic form of RasH by mutations in the GAP binding/"effector" domain

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Biological properties of human c-Ha-ras1 genes mutated at codon 12.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The stereochemistry of the water molecules in the hydrates of small biological molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Time-resolved FTIR studies of the GTPase reaction of H-ras p21 reveal a key role for the beta-phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystallographic R factor refinement by molecular dynamics

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The CCP4 suite: programs for protein crystallography

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

xdlMAPMAN and xdlDATAMAN - programs for reformatting, analysis and manipulation of biomacromolecular electron-density maps and reflection data sets

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The Protein Data Bank: a computer-based archival file for macromolecular structures

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2980021-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0969-2126(00)80021-0

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10574788%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10574788%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q27620456&oldid=1980193810"