(Q52538724)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7719852%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

title

Substrate-assisted catalysis as a mechanism for GTP hydrolysis of p21ras and other GTP-binding proteins (English)

1 reference

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24 October 2019

2

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24 October 2019

Hans Robert Kalbitzer

5

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24 October 2019

4

Warshel A

1 reference

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24 October 2019

author name string

Schweins T

1

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24 October 2019

Scheffzek K

3

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24 October 2019

Wittinghofer A

6

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24 October 2019

publication date

1 January 1995

1 reference

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Nature structural biology

24 October 2019

published in

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24 October 2019

volume

2

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24 October 2019

page(s)

36-44

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24 October 2019

issue

1

1 reference

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The GTPase superfamily: a conserved switch for diverse cell functions

24 October 2019

cites work

1 reference

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Function and regulation of ras.

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Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

21 January 2018

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Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro

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Mammalian Ras interacts directly with the serine/threonine kinase Raf

21 January 2018

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Proteins regulating Ras and its relatives

21 January 2018

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Biological and biochemical properties of human rasH genes mutated at codon 61.

21 January 2018

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Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation

21 January 2018

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The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product.

21 January 2018

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The 2.2 A crystal structure of transducin-alpha complexed with GTP gamma S

21 January 2018

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Three-dimensional structures of H-ras p21 mutants: molecular basis for their inability to function as signal switch molecules

21 January 2018

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Mutational and kinetic analyses of the GTPase-activating protein (GAP)-p21 interaction: the C-terminal domain of GAP is not sufficient for full activity

21 January 2018

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Differential regulation of rasGAP and neurofibromatosis gene product activities

21 January 2018

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GTPase mechanism of Gproteins from the 1.7-A crystal structure of transducin alpha-GDP-AIF-4

21 January 2018

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Aluminofluoride and beryllofluoride complexes: a new phosphate analogs in enzymology

21 January 2018

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Analysis of the fibroblast transformation potential of GTPase-deficient gip2 oncogenes

21 January 2018

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GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours.

21 January 2018

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Crystal structure of active elongation factor Tu reveals major domain rearrangements

21 January 2018

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Experimental designs for estimating the parameters of the Michaelis-Menten equation from progress curves of enzyme-catalyzed reactions

21 January 2018

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Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis

21 January 2018

1 reference

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Complex formation between RAS and RAF and other protein kinases

21 January 2018

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Biological properties of human c-Ha-ras1 genes mutated at codon 12.

31 March 2020

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Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins

31 March 2020

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Direct Brønsted analysis of the restoration of activity to a mutant enzyme by exogenous amines

31 March 2020

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Quantitative analysis of structure–activity relationships in engineered proteins by linear free-energy relationships

31 March 2020

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Role of glutamine-61 in the hydrolysis of GTP by p21H-ras: an experimental and theoretical study.

31 March 2020

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Probing the structure and mechanism of Ras protein with an expanded genetic code

31 March 2020

1 reference

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On the mechanism of guanosine triphosphate hydrolysis in ras p21 proteins

31 March 2020

1 reference

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Analysis of the transforming potential of the human H-ras gene by random mutagenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0195-36

Mechanism of GTP hydrolysis by G-protein alpha subunits

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0195-36

Why have mutagenesis studies not located the general base in ras p21.

31 March 2020

1 reference

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Structural basis for transfer RNA aminoacylation by Escherichia coli glutaminyl-tRNA synthetase

31 March 2020

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The catalytic mechanism of Escherichia coli aspartate carbamoyltransferase: a molecular modelling study.

31 March 2020

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Substrate-assisted catalysis in the cleavage of DNA by the EcoRI and EcoRV restriction enzymes

31 March 2020

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Three-dimensional structures and properties of a transforming and a nontransforming glycine-12 mutant of p21H-ras

31 March 2020

1 reference

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Site-directed mutagenesis and the role of the oxyanion hole in subtilisin

31 March 2020

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Evaluation of catalytic free energies in genetically modified proteins

31 March 2020

1 reference

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Contribution of the glutamine 19 side chain to transition-state stabilization in the oxyanion hole of papain

31 March 2020

1 reference

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Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSB0195-36

Structure of the complex between adenylate kinase from Escherichia coli and the inhibitor Ap5A refined at 1.9 A resolution. A model for a catalytic transition state

31 March 2020

1 reference

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The crystal structure of elongation factor EF-Tu from Thermus aquaticus in the GTP conformation

31 March 2020

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Substitution of histidine-84 and the GTPase mechanism of elongation factor Tu.

31 March 2020

1 reference

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Crystallization and preliminary X-ray analysis of the human c-H-ras-oncogene product p21 complexed with GTP analogues

31 March 2020

1 reference

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Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis

31 March 2020

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1038/NSB0195-36

Identifiers

DOI

10.1038/NSB0195-36

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7719852%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

1 reference